Metabolic evaluation on Sakiz ewes with still and live births without etiological diagnosis

Year 2022, Volume: 7 Issue: 1, 51 - 57, 30.04.2022

Feyyaz Kaya Gökhan Bozkurt

https://doi.org/10.24880/maeuvfd.1057529

Cited By: 1

Abstract

In this study, it was aimed to compare the differences in the metabolic status of grazing ewes with live and stillbirth lambs for which no etiological infectious agent could be isolated. Group 1 (live and stillbirth lambs) and group 2 (live lambs) consisted of 20 multiparous Sakiz ewes. Blood samples were collected two times on the parturition day and the day fifteenth after parturition. In the first sampling time, triglyceride levels of group 2 were determined significantly (p<0.001) higher than group 1. In the second sampling time, levels of magnesium (p<0.05), total protein (P<0.01), cholesterol (p<0.01), and triglyceride (p<0.05) levels were found significantly higher in group 2 than group 1. However, significant decreases were observed in both calcium and triglyceride levels in group 2 between the two sampling times. The beta-hydroxybutyric acid (BHBA) (p<0.05) levels were found significantly higher in the second sampling time than in the first sampling time only in group 1. Unlike the BHBA levels, a significant decrease was determined in both cholesterol and aspartate aminotransferase (AST) levels (p<0.05) in group 1 as the lactation progressed. Finally, we concluded that the metabolic status of group 2 is better than group 1, and it is important to the evaluation and follow-up of the metabolism in ewes with stillbirth without any etiological diagnose that couldn’t be determined.

Keywords

Ewes, stillbirth, reproduction, metabolism, cholesterol, triglyceride

Project Number

YOK

References

• 1. Ali, S., Zhao, Z., Zhen, G., Kang, J.Z. & Zi Yi, P. (2019). Reproductive problems in small ruminants (Sheep and goats) a substantial economic loss in the world. Large Animal Review, 25(6), 215-223.
• 2. Yilmaz, H., Crips, P.J., Turan, N., Ozgur, N.Y., Green, L.E., Anil, M.H., Ilgaz, A., & Morgan, K.L. (2002). A postal survey of abortion in Turkish sheep. Small Ruminant Research, 45(2), 151-158. https://doi.org/10.1016/S0921-4488(02)00094-9
• 3. Dun, K. (2019). Ovine abortion-causes and diagnosis. Livestock, 24(1), 44–50. https://doi.org/10.12968/live.2019.24.1.44
• 4. Clune, T., Beetson, S., Besier, S., Knowles, K., Paskin, R., Rawlin, G., Suter, R., & Jacobson, C. (2021). Ovine abortion and stillbirth investigations in Australia. Australian Veterinary Journal, 99(3), 72-78. https://doi.org/10.1111/avj.13040
• 5. Mearns, R. (2008). Abortion in sheep. 1. Investigation and principal causes. In Practice 2007; 29 (1), 40-46. https://doi.org/10.1136/inpract.29.1.40
• 6. Mavrogianni, V.S., & Brozos, C. (2008). Reflections on the causes and the diagnosis of peri-parturient losses of ewes. Small Ruminant Research, 76(1-2), 77–82. https://doi.org/10.1016/j.smallrumres.2007.12.019
• 7. Kiran, S., Bhutta, A.M., Khan, B.A., Durrani, S., Ali, M., & Iqbal, F. (2012). Effect of age and gender on some blood biochemical parameters of apparently healthy small ruminants from Southern Punjab in Pakistan. Asian Pacific Journal of Tropical Biomedicine, 2(4), 304-306. https://doi.org/10.1016/S2221-1691(12)60028-8
• 8. Cabiddu, A., Dattena, M., Decandia, M., Molle, G., Lopreiato, V., Minuti, A., & Trevisi, E. (2019). The effect of parity number on the metabolism, inflammation, and oxidative status of dairy sheep during the transition period. Journal of Dairy Science, 103(9), 8564-8575. https://doi.org/10.3168/jds.2019-18114
• 9. Karapehlivan, M., Atakisi, E., Atakisi, O., Yucayurt, R., & Pancarci, S.M. (2007). Blood biochemical parameters during the lactation and dry period in Tuj ewes. Small Ruminant Research, 73(1-3), 267-271. https://doi.org/10.1016/j.smallrumres.2006.12.006
• 10. Ulcar, I., & Celeska, I. (2010). Seasonal variations of serum biochemical parameters in dairy cows. Macedonian Veterinary Review, 33: 30.
• 11. Kirkbride, A.C. (1992). Etiologic agents detected in a 10-year study of bovine abortions and stillbirths. Journal of Veterinary Diagnostic Investigation, 4(2), 175-180. https://doi.org/10.1177/104063879200400210
• 12. Fthenakis, G.C., Arsenos, G., Brozos, C., Fragkou, I.A., Giadinis, N.D., Giannenas, I., Mavrogianni, V.S., Papadopoulous, E., & Valasi, I. (2012). Health management of ewes during pregnancy. Animal Reproduction Science, 130(3-4), 198-212. https://doi.org/10.1016/j.anireprosci.2012.01.016
• 13. Kirkbride, C.A. (1993). Diagnoses in 1,784 ovine abortions and stillbirths. Journal of Veterinary Diagnostic Investigation, 5(3), 398-402. https://doi.org/10.1177/104063879300500316
• 14. Marutsova, V., & Marutsov, P. (2018). Subclinical and clinical ketosis in sheep-relationships between body condition scores and blood B-hydroxybutyrate and non-esterifed fatty acids concentrations. Tradition and Modernity in Veterinary Medicine, 4, 30-36.
• 15. Nazifi, S., Saeb, M., & Ghavami, M. (2002). Serum lipid profile in Iranian fat-tailed sheep in late pregnancy, at parturition and during the postparturion period. Journal Veterinary Medicine, 49(1), 9-12. https://doi.org/10.1046/j.1439-0442.2002.00405.x
• 16. Carcangiu, V., Vacca, G.M., Mura, M.C., Dettori, M.L., Pazzola. M., et al. Blood parameters during lactation and dry period in sarda sheep breed. In: Proceed Atti XV Congresso Fe.Me.S.P.Run. Kusadasi, Turkey; 2007. 15-20.
• 17. Piccione, G., Caola, G., Giannetto, C., Grasso, F., Runzo, S.C., & Zumbo, A. (2009). Selected biochemical serum parameters in ewes during pregnancy, post-parturition, lactation and dry period. Animal Science Papers and Reports, 27(4), 321-330.
• 18. Ramos, J.J., Verde, M.T., Marca, M.C., & Fernández, A. (1994). Clinical chemical values and variations in Rasa Argonesa ewes and lambs. Small Ruminant Research, 13(2), 133-139. https://doi.org/10.1016/0921-4488(94)90088-4
• 19. Antunovic, Z., Novoselec, J., Speranda, M., Vegara, M., Pavic, V., Mioc, B., & Djidara, M. (2011). Changes in biochemical and hematological parameters and metabolic hormones in Tsigai ewes blood in the first third of lactation. Archiv fur Tierzucht; 54(5), 535-545. https://doi.org/10.5194/aab-54-535-2011
• 20. Khaki, Z., Khazraiinia, P., Chegini, S., & Khazraee Nia, S. (2012). Comparative study of serum lipid profile in chicken, ostrich, cattle, and sheep. Comperative Clinical Pathology, 21, 259–263. doi: 10.1007/s00580-010-1088-0
• 21. Gonzalez, F.D., Munio, R., Pereira, V., Campos, R., & Benedito J.l. (2011). Relationship among blood indicators of lipomobilization and hepatic function during early lactation in high- yielding dairy cows. Journal of Veterinary Science, 12 (3): 251-255. DOI: https://doi.org/10.4142/jvs.2011.12.3.251
• 22. Sordillo, L.M., & Raphae, l.W. (2013). Significance of metabolic stress, lipid mobilization and inflammation on transition cow disorders. Veterinary Clinics North America Food Animal, 29 (2), 267–278. https://doi.org/10.1016/j.cvfa.2013.03.002
• 23. Duffield, T.F. (2000). Subclinical ketosis in lactating dairy cattle. Veterinary Clinics North America Food Animal, 16(2), 231-252. https://doi.org/10.1016/S0749-0720(15)30103-1
• 24. Dzadzovski, I., Celeska., I, Ulchar, I., Janevski, A., & Kirovski, D. (2015). Influence of the season on the metabolic profile in Chios sheep. Macedonian Veterinary Review, 38(2), 183-188.
• 25. Pancarci, Ş.M., Kaçar, C, Öğün, M., Güngör, Ö., Gürbulak K., Oral H., Karapehlivan, M., & Çitil, M. (2007). Effect of L-carnitine administration on energy metabolism during periparturient period in ewes. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 13(2), 149-154. doi:10.9775/kvfd.2007.26-A
• 26. Raoofi, A., Jafarian, M., Safi, S,. & Vatankhah, M. (2013). Fluctuations in energy-related metabolites during the peri-parturition period in Lori-Bakhtiari ewes. Small Ruminant Research, 109(1), 64-68. https://doi.org/10.1016/j.smallrumres.2012.06.012
• 27. Kadzere, C.T., Llewelyn, C.A., & Chivandi, E. (1997). Plasma progesterone, calcium, magnesium and zinc concentrations from oestrus synchronization to weaning in indigenous goats in Zimbabwe. Small Ruminant Research 24 (1), 21-26. https://doi.org/10.1016/S0921-4488(96)00933-9
• 28. Gürgöze, S.Y., Zonturlu, A.K.., Özyurtlu, N., & İçen, H. (2009). Investigation of some biochemical parameters and mineral substance during pregnancy and postpartum period in Awassi Ewes. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 15(6), 957-963.
• 29. Treacher, T.T., & Caja, G. (2002). Nutrition during lactation. In: ‘Sheep nutrition’. M Freer, H Dove (editor) UK, Wallingford: CAB International.
• 30. Borella, P., Szilagyi, A., Than, G., Csaba, A., Giardino, A. & Fachinetti F. (1990). Maternal plasma concentrations of magnesium, calcium, zinc and copper in normal and pathological pregnancies. The Science of the Total Environment, 99(1-2), 67-76. doi: 10.1016/0048-9697(90)90212-d
• 31. Altura, B.M., Altura, B.T., & Carella, A. (1983). Magnesium deficiency-induced spasms of umbilical vessels: relation to preeclampsia, hypertension, growth retardation. Science, 221(4608), 376-377. Doi: 10.1126/science.6867714
• 32. Omidi, A. (2015). Etiologic Evaluation of Late Term Abortions or Stillbirths in Some Small Ruminant Flocks of South Khorasan Province, Iran. Journal of the Faculty of Veterinary Medicine Istanbul University; 41(2):199-204. Doi: 10.16988/iuvfd.2015.57738
• 33. Caldeira, R.M., Vaz Portugal, A. (1991). Interrelationship between body condition and metabolic status in ewes. Small Ruminant Research, 6(1-2), 15–24. Doi:10.1016/0921-4488(91)90003-9
• 34. Aytekin, I., Aksit, H., Sait, A., Kaya, F., Aksit, D., Gokmen, M., & Baca, A.U. (2015). Evaluation of oxidative stress via total antioxidant status, sialic acid, malondialdehyde and RT-PCR findings in sheep affected with bluetongue. Veterinary Record Open (1), 2:e000054. 10.1136/vetreco-2014-000054
• 35. Caldeira, R.M., Belo, A.T., Santos, C.C., Vazques, M.I., & Portugal, A.V. (2007). The effect of body condition score on blood metabolites and hormonal profiles in ewes. Small Ruminant Research, 68(3), 233-241. https://doi.org/10.1016/j.smallrumres.2005.08.027