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Developmental disorders caused by Verbascum speciosum Schrad. Extracts in Drosophila melanogaster (Diptera: Drosophilidae)

Year 2012, Volume: 3 Issue: 2, 7 - 11, 21.12.2015

Hasan Uysal Özkan Aksakal Hakan Askın

Abstract

The effect of aqueous seed extracts of Verbascum speciosum on the development biology of Drosophila melanogaster was determined. Various doses of boiled and unboiled extracts (2, 4, 6, 8 and 10 mg/100 mL standard
Drosophila medium (SDM)) were added to the standard medium of D. melanogaster. The use of the seed extracts significantly increased the mortality of the F1 generation. Emerged individuals belonging to F1 decreased with an
increase in dose (P<0.05). In addition, severe malformations were observed belonging to different extremities in the newly-emerged flies of F1 progeny. The results showed that unboiled seed extracts of V. speciosum are more toxic to
D. melanogaster than their boiled counterpart (Vsb<Vsub).


Keywords: Drosophila melanogaster, Verbascum speciosum, developmental biology, mortality

Keywords

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References

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  • Akdemir, Z.S., Tatli, I.I., Bedir, E., Khan, I.A. (2005). Two new iridoid glycosides from Verbascum salviifolium, Boiss. Zeitschrift fur Naturforschung B, 60, 113–117.
  • Baytop, T. (1999). Therapy with Medicinal Plants in Turkey (Past and Present), Nobel Tıp Kitabevleri Ltd., İstanbul, pp. 334.
  • Beard, R.L, Walton, G.S. (1971). Insecticidal mycotoxins produced by Aspergillus flavus var. colunaris. Bull Conn Agr Exp Sta, 725, 1-26.
  • Dulger, B., Kirmizi, S., Arslan, H., Güleryüz, G. (2007). Antimicrobial Verbascum species. Pharm Biol, 40, 587–589. of three endemic
  • Elgindi, M.R., Mabry, T.J. (2000). Phenyletanoid glycosides from Verbascum siniaticum. Asian J Chem, 12, 127–130.
  • Giner, R.M., Villalba, M.L., Recio, M.C., Manez, S., Cerda-Nicolas, M., Rios, J.L. (2000). Anti- inflammatory glycoterpenoids from Scrophularia auriculata. Eur J Pharm, 389, 243–252.
  • Graf, U., Würgler, F.E., Katz, A.J., Frei, H., Juon, H., Hall, C.B., Kale, P.G. (1984). Somatic mutation and melanogaster. Environ Mutagen, 6 (2), 153-188. test in Drosophila
  • Hartleb, I., Seifert, K. (1994). Sangarosaponin-D a triterpenoid saponin from Verbacsum songaricu. Phytochem, 35, 1009–1011.
  • Huber-Morath, A. (1978). Verbascum in Flora of Turkey and The East Aegean Islands, Vol. 6, Ed: Davis, P.H., University Press, Edinburgh, pp. 461-603.
  • Jeyabalan, D., Arul, N., Thangamathi, P. (2003). Studies on effects of Plargonium citrosa leaf extracts on malarial vector, Anopheles stephensi Liston. Bioresour Technol, 89, 185-189.
  • Khoshnoud, H., Khayamy, M. (2008). Insecticidal effects of cheiranthifolium Boiss. against two stored-product insect pests species. J Biol Sci, 8(1), 191-195.
  • Khoshnoud, H., Ghiyasi, M., Amirnia, R., Fard, SS. (2008). The potential of using insecticidal properties of medicinal plants against insect pest. Pak J Biol Sci, 11(10), 1380-1384.
  • Klimek, B. (1996). Hidroxycinnamoyl ester glycosides and saponins from flowers of Verbascum phlomoides. Phytochem, 43, 1281–1284.
  • Konoshima, T., Takasaki, M., Tokuda, H., Nishimo, H. (2000). Cancer chemopreventive activity of an iridoid glycoside, 8-acetylharpagide from Ajuga decumbens. Cancer Lett, 157, 87–92.
  • Kupeli, E., Tatli, I.I., Akdemir, Z.S., Yesilada, E. (2007). Bioassay-guided isolation of anti-inflammatory and antinociceptive glycoterpenoids from the flowers of Verbascum lasianthum Boiss. ex Bentham. J Ethnopharmacol, 110, 444-450.
  • Mostafa, T.Y., Mahgoub, S.M., Ahmed, M.S. (1996). The efficiency of certain plant powders against cowpea weevil Callosobruchus maculates (F.) (Coleoptera: Bruchidae). Egypt J Agric Res, 74, 307-319.
  • Paszkiewicz-Gadek, A., Grochowska, K., Galasinski, W. (1990). Effect of the aqueous extract and saponin fraction from the flowers of Verbascum thapsiforme on protein biosynthesis in a rat liver ribosomal system. Phytother Res, 4 (5), 177–181.
  • Sadek, M.M. (2003). Antifeedant and toxicity of Adhatoda vasica leaf extract against Spodoptera littoralis (Lep., Noctuidae). J. Applied Entomol, 127, 396-404.
  • Schmutterer, H. (1995). The neem tree Azadirachta indica A. juss and other malicious plant sources of unique natural products of integrated pest management medicine, industry and other purposes,VCH, Veinheim, Federal Republic of Germany.
  • Skaltsounis, A.L., Tsitsa-Tzardis, E., Demetzos, C., Harvala, C. (1996). Unduloside, a new iridoid glycoside from Verbascum undulatum. J Nat Prod, 59, 673–675.
  • Stevenson, P.C., Simmonds, M.S.J., Sampson, J., Houghton, P.J., Grice, P. (2002). Wound healing activity of acylated iridoid glycosides from Scrophularia nodosa. Phytother Res, 16, 33–35.
  • Tatli, I.I., Akdemir, Z.S., Bedir, E. (2003). 6-O-l- Rhamnopyranosylcatalpol derivative iridoids from Verbascum cilicicum. Turk J Chem, 27, 765–772.
  • Tatli, I.I., Akdemir, Z.S. Bedir, E. (2004). Saponin, iridoid, glycosides from Verbascum pterocalycinum var. mutense. Turk J Chem, 28, 111–122.
  • Turker, A.U., Gurel, E. (2005). Common Mullein (Verbascum thapsus L.) Recent Advances in Research, Phytother Res, 19, 7-13.
  • Uysal, H., Kaya, Y. (2004). Toxicity of Euphorbia canariensis latex to some developmental stages of Drosophilidae). Bull Environ Contam Toxicol, 72, 45-53. Diptera:
  • Vijayavitthal, T.M., Kanwal, R., Amiya, P.B., Ragini, S., Anju, P., Lalit, M.T., Vishwa, M.L.S. (1998). Studies on the profile of immunostimulant activities of modified iridoid glycosides. Bioorg Med Chem, 6, 605–611.
  • Youhnovski, N., Dandarov, K., Guggisberg, A., Hesse, M. (1999). Macrocyclic spermine alcholoids from Verbascum Isolation, structure elucidation and synthesis of the (E/Z)-isomeric pairs(S)- verbasikrine/(S)- verbamekrine/(S)-isoverbamekrine, Helv Chim Acta, 82, 1185–1194. and (S)
  • Zhong, G.H., Hu, M.Y., Weng, A.Q. (2001). Laboratory and Rhododendron molle flowers as insect growth regulator to imported cabbage worm, Pieris rapae L. (Lepidoptera:Pieridae). J Appl Entomol, 125, 563-596.

Developmental disorders caused by Verbascum speciosum Schrad. Extracts in Drosophila melanogaster (Diptera: Drosophilidae)

Year 2012, Volume: 3 Issue: 2, 7 - 11, 21.12.2015

Hasan Uysal Özkan Aksakal Hakan Askın

Abstract

Bu çalışmada, Drosophila melanogaster’in gelişim biyolojisi üzerine Verbascum speciosum’a ait tohumların su ekstraktlarının etkileri araştırılmıştır. Bu amaçla, kaynatılmış ve kaynatılmamış tohum ekstraktlarının farklı dozları (2, 4, 6, 8 ve 10 mg/100 mL SDB) D. melanogater’in standart besiyerine ilave edilmiştir. Bu ekstraktların kullanılmasıyla F1 neslinde ölüm oranının önemli bir ölçüde arttığı gözlenmiştir. Doz artışına bağlı olarak F1 nesline ait birey sayısı azalmıştır (P

Keywords

Verbascum speciosum Drosophila melanogaster gelişim biyolojisi mortalite

References

  • Ahmed, B., Al-Rehaily, A.J., Al-Howiriny, T.A., El-Sayed, K.A., Ahmad, M.S. (2003). Scropolioside-D2 and harpagoside -B: two new iridoid glycosides from Scrophularia deserti and their antidiabetic and anti-inflammatory activity. Biol Pharm Bull, 26, 462–467.
  • Akdemir, Z.S., Tatli, I.I., Bedir, E., Khan, I.A. (2005). Two new iridoid glycosides from Verbascum salviifolium, Boiss. Zeitschrift fur Naturforschung B, 60, 113–117.
  • Baytop, T. (1999). Therapy with Medicinal Plants in Turkey (Past and Present), Nobel Tıp Kitabevleri Ltd., İstanbul, pp. 334.
  • Beard, R.L, Walton, G.S. (1971). Insecticidal mycotoxins produced by Aspergillus flavus var. colunaris. Bull Conn Agr Exp Sta, 725, 1-26.
  • Dulger, B., Kirmizi, S., Arslan, H., Güleryüz, G. (2007). Antimicrobial Verbascum species. Pharm Biol, 40, 587–589. of three endemic
  • Elgindi, M.R., Mabry, T.J. (2000). Phenyletanoid glycosides from Verbascum siniaticum. Asian J Chem, 12, 127–130.
  • Giner, R.M., Villalba, M.L., Recio, M.C., Manez, S., Cerda-Nicolas, M., Rios, J.L. (2000). Anti- inflammatory glycoterpenoids from Scrophularia auriculata. Eur J Pharm, 389, 243–252.
  • Graf, U., Würgler, F.E., Katz, A.J., Frei, H., Juon, H., Hall, C.B., Kale, P.G. (1984). Somatic mutation and melanogaster. Environ Mutagen, 6 (2), 153-188. test in Drosophila
  • Hartleb, I., Seifert, K. (1994). Sangarosaponin-D a triterpenoid saponin from Verbacsum songaricu. Phytochem, 35, 1009–1011.
  • Huber-Morath, A. (1978). Verbascum in Flora of Turkey and The East Aegean Islands, Vol. 6, Ed: Davis, P.H., University Press, Edinburgh, pp. 461-603.
  • Jeyabalan, D., Arul, N., Thangamathi, P. (2003). Studies on effects of Plargonium citrosa leaf extracts on malarial vector, Anopheles stephensi Liston. Bioresour Technol, 89, 185-189.
  • Khoshnoud, H., Khayamy, M. (2008). Insecticidal effects of cheiranthifolium Boiss. against two stored-product insect pests species. J Biol Sci, 8(1), 191-195.
  • Khoshnoud, H., Ghiyasi, M., Amirnia, R., Fard, SS. (2008). The potential of using insecticidal properties of medicinal plants against insect pest. Pak J Biol Sci, 11(10), 1380-1384.
  • Klimek, B. (1996). Hidroxycinnamoyl ester glycosides and saponins from flowers of Verbascum phlomoides. Phytochem, 43, 1281–1284.
  • Konoshima, T., Takasaki, M., Tokuda, H., Nishimo, H. (2000). Cancer chemopreventive activity of an iridoid glycoside, 8-acetylharpagide from Ajuga decumbens. Cancer Lett, 157, 87–92.
  • Kupeli, E., Tatli, I.I., Akdemir, Z.S., Yesilada, E. (2007). Bioassay-guided isolation of anti-inflammatory and antinociceptive glycoterpenoids from the flowers of Verbascum lasianthum Boiss. ex Bentham. J Ethnopharmacol, 110, 444-450.
  • Mostafa, T.Y., Mahgoub, S.M., Ahmed, M.S. (1996). The efficiency of certain plant powders against cowpea weevil Callosobruchus maculates (F.) (Coleoptera: Bruchidae). Egypt J Agric Res, 74, 307-319.
  • Paszkiewicz-Gadek, A., Grochowska, K., Galasinski, W. (1990). Effect of the aqueous extract and saponin fraction from the flowers of Verbascum thapsiforme on protein biosynthesis in a rat liver ribosomal system. Phytother Res, 4 (5), 177–181.
  • Sadek, M.M. (2003). Antifeedant and toxicity of Adhatoda vasica leaf extract against Spodoptera littoralis (Lep., Noctuidae). J. Applied Entomol, 127, 396-404.
  • Schmutterer, H. (1995). The neem tree Azadirachta indica A. juss and other malicious plant sources of unique natural products of integrated pest management medicine, industry and other purposes,VCH, Veinheim, Federal Republic of Germany.
  • Skaltsounis, A.L., Tsitsa-Tzardis, E., Demetzos, C., Harvala, C. (1996). Unduloside, a new iridoid glycoside from Verbascum undulatum. J Nat Prod, 59, 673–675.
  • Stevenson, P.C., Simmonds, M.S.J., Sampson, J., Houghton, P.J., Grice, P. (2002). Wound healing activity of acylated iridoid glycosides from Scrophularia nodosa. Phytother Res, 16, 33–35.
  • Tatli, I.I., Akdemir, Z.S., Bedir, E. (2003). 6-O-l- Rhamnopyranosylcatalpol derivative iridoids from Verbascum cilicicum. Turk J Chem, 27, 765–772.
  • Tatli, I.I., Akdemir, Z.S. Bedir, E. (2004). Saponin, iridoid, glycosides from Verbascum pterocalycinum var. mutense. Turk J Chem, 28, 111–122.
  • Turker, A.U., Gurel, E. (2005). Common Mullein (Verbascum thapsus L.) Recent Advances in Research, Phytother Res, 19, 7-13.
  • Uysal, H., Kaya, Y. (2004). Toxicity of Euphorbia canariensis latex to some developmental stages of Drosophilidae). Bull Environ Contam Toxicol, 72, 45-53. Diptera:
  • Vijayavitthal, T.M., Kanwal, R., Amiya, P.B., Ragini, S., Anju, P., Lalit, M.T., Vishwa, M.L.S. (1998). Studies on the profile of immunostimulant activities of modified iridoid glycosides. Bioorg Med Chem, 6, 605–611.
  • Youhnovski, N., Dandarov, K., Guggisberg, A., Hesse, M. (1999). Macrocyclic spermine alcholoids from Verbascum Isolation, structure elucidation and synthesis of the (E/Z)-isomeric pairs(S)- verbasikrine/(S)- verbamekrine/(S)-isoverbamekrine, Helv Chim Acta, 82, 1185–1194. and (S)
  • Zhong, G.H., Hu, M.Y., Weng, A.Q. (2001). Laboratory and Rhododendron molle flowers as insect growth regulator to imported cabbage worm, Pieris rapae L. (Lepidoptera:Pieridae). J Appl Entomol, 125, 563-596.
There are 29 citations in total.

Details

Primary Language English
Journal Section Research Paper
Authors

Hasan Uysal This is me

Özkan Aksakal This is me

Hakan Askın

Publication Date December 21, 2015
Published in Issue Year 2012 Volume: 3 Issue: 2

Cite

APA Uysal, H., Aksakal, Ö., & Askın, H. (2015). Developmental disorders caused by Verbascum speciosum Schrad. Extracts in Drosophila melanogaster (Diptera: Drosophilidae). Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 3(2), 7-11.