Alkaloids from Mushrooms

Year 2018, Volume: 9 Issue: 2, 117 - 125, 25.10.2018

Büşra Fendoğlu Ayşe Kuruüzüm-uz , Didem Şöhretoğlu

Abstract

Mushrooms (macrofungi) are
a part of the human diet as a source of both food and medicine for centuries
especially in East-Asia. The use of mushrooms and their extracts for medicinal
purposes became more popular due to increasing number of research conducting on
them recently. They predominantly contain polysaccharides, terpenes and
sterols. Alkaloids exhibits bioactive effects even in very small doses and
mainly distributed in Angiosperms. Their occurrences in macrofungi is very
limited and not very-well documented as much as other constituents like
polysaccharides or terpenes. In this review, we focused on distribution and
bioactivities of mushroom alkaloids.

Keywords

macrofungi, alkaloid, Mycena, psilocybin, erinacerin, pyriferine

Mantarlardan Elde Edilen Alkaloitler

Abstract

Mantarlar (makrofunguslar) besin kaynağı ve ilaç
olarak özellikle Doğu Asya’da yüzyıllardır diyetin bir parçasıdır. Son
zamanlarda üzerlerinde yapılan çalışmaların sayısının artması nedeniyle
mantarların ve ekstrelerinin tıbbi amaçla kullanımı daha popüler hale
gelmiştir. Mantarlar çoğunlukla polisakkaritler, terpenler ve steroller
taşımaktadır. Alkaloitler çok düşük dozlarda bile biyoaktif etki gösterirler ve
genellikle Angiospermlerde bulunurlar. Bu grup bileşiklerin makrofunguslarda
bulunuşları oldukça sınırlıdır ve haklarında polisakkaritler ya da terpenler
gibi diğer bileşiklerin mantarlarda yayılışları kadar detaylı bilgi yoktur. Bu
derlemede, mantarlarda bulunan alkaloitlerin dağılımı ve biyoaktivitelerine
odaklandık.

Keywords

makrofungus, alkaloit, Mycena, psilosibin, erinaserin, piriferin

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