Placenta-derived cells: A new source for regenerative medicine application

Year 2025, Volume: 38 Issue: 2, 90 - 97, 30.05.2025

Nguyen Quan , Bui Thi Kim Ly , Hoang Thanh Chi

https://doi.org/10.5472/marumj.1708020

Abstract

The placenta is the first and most important organ of pregnancy. It is the communication bridge between the mother and fetus.
Placental elements, due to their important position and function, are specially designed to manage the exchange of nutrients and
the local regulation of the maternal immune system. The development of cells such as cytotrophoblasts, syncytiotrophoblasts,
extravillous trophoblasts, placental giant trophoblasts, placental macrophages, and placenta-derived mesenchymal stromal cells is
described. Medical researches have been performed to demonstrate the curative potential properties of these cells, such as treating
burns, tendon and joint diseases, lung diseases, blood and bone marrow diseases, and other diseases. This review provides an overview
of the formation and development of placental cell lines and their potential for regenerative medicinal research and ongoing clinical
applications.23-01-2024

Keywords

Placenta, Placental MSC, Application, Clinical trial

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