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MULTİPL MENİNGİOMALARDA RADYOLOJİK BULGULAR

Year 2006, Volume: 7 Issue: 3, 35 - 38, 01.12.2006

Abstract

Bu çalışmanın amacı, Recklinghausen hastalığı dışında nadir görülen Multipl Meningioma'lı (MM) hastalarınBT (Bilgisayarlı Tomografi) ve MRG (Manyetik Rezonans Görüntüleme) bulgularını incelemektir.Ailesinde Recklinghausen hastalığı öyküsü olmayan, farklı nörolojik şikayetleri olan toplam 7 kadın hasta (yaşortalaması: 49.28) çalışmaya dahil edildi. Bu hastaların 7'sine MRG ve ayrıca 1'sine de BT yapıldı.Lokalizasyon, intensite, kontrastlanma paternleri (dural boyanma) ve çevre dokuya invazyon özellikleriincelendi.MM'ların lokalizasyonlarına göre dağılımında; 4 lezyon konveksite düzeyinde, 3 lezyon parasagital alanda, 1lezyon olfaktor olukda, 1 lezyon tentoryumda ve 1 lezyon da sellar lokalizasyondaydı. MRG'de tüm olgularda T1ağırlıklı sekanslarda hipointens, T2 ağırlıklı sekanslarda hiperintens, paramanyetik kontrast madde sonrasıyoğun ve homojen kontrast tutulumları (4 olguda dural boyanma) gösteren multipl extra aksiyel kitle lezyonlarıizlendi. BT karakteristikleri MRG ile benzer olarak izlendi.Meningiomalar duramaterden köken alan beynin en yaygın extraaksial tümörleri olup Recklinghausen hastalığıdışında multipl olarak çok nadir görülürler. MM patogenezi tam olarak bilinmemekle beraber bizimçalışmamızda olduğu gibi kadınlarda daha sık görülmesi nedeniyle hormonal faktörlerin etkili olabileceği iddiaedilmektedir

References

  • 1. Domenicucci M, Santoro A, D'Osvaldo DH, Delfini R, Cantore GP, Guidetti B. Multiple intracranial meningiomas. J Neurosurg 1989; 70:41-4
  • 2. Nasher HC, Grote W, Lohr E, Gerhardt L. Multiple meningiomas. Clinical and computer tomographic observations. Neuroradiology 1981; 21:259-63
  • 3. Spallone A, Neroni M, Giuffre R. Multiple skull base meningioma: case report. Surg Neurol 1999; 51:274- 80.
  • 4. Butti G, Assietti R, Casalone R, Paoletti P. Multiple meningiomas: a clinical, surgical, and cytogenetic analysis. Surg Neurol 1989;31:255-60.
  • 5. Locatelli D, Bottoni A, Uggetti C, Gozzoli L. Multiple meningiomas evaluated by computed tomography. Neurochirurgia (Stuttg) 1987; 30:8-10.
  • 6. Sheehy JP, Crockard HA. Multiple meningiomas: a long-term review. J Neurosurg 1983; 59:1-5.
  • 7. Borovich B, Doron Y, Braun J, et al. The incidence of multiple meningiomas--do solitary meningiomas exist?Acta Neurochir (Wien) 1988; 90:15-22.
  • 8. Anfimow J, Blumenau L. Ein Fall: multipler Geschwulste in der Schadelhöhle. Neurol Zentralbl 1889; 8:585
  • 9. Cushing H, Eisenhardt L: Meningiomas: their classification,regional behavior , life history and surgical end results, NewYork: Hafner, 1938, reprinted 1969: 224 249
  • 10. Basso AJ, Carrizo A. Sphenoid ridge meningiomas: Schmidek HH. Meningiomas and their surgical management. Philadelphia: WB Saunders, 1991:242- 259
  • 11. Stein ME, Druemea K, Guilbord JN, Kuten A. Lateagressive meningioma following prophlactic cranial irradiation for acute lymphoblastic leukaemia. Br J Radiol 1995; 68:1123-25
  • 12. Desai R, Bruce J. Meningiomas of the cranial base. J Neuro-Oncol 1994; 20:255-279
  • 13. KleinschmidtDeMasters BK, Lillihei KO. Radiation induced meningioma with a 63 year latency period: case report. J Neurosurg 1995; 82:487-488
  • 14. Lawrens E, Dixon M. Meningiomas imaging. Neurosurgery. McGraw-Hill. 1996: 855-872.
  • 15. Rosen CL. Meningiomas: the role of preoperative angiography and embolization. Neurosurg Focus 2003;15:1
  • 16. Kandel E, Sungurov E, Morgunov M. Cerebral and two spinal meningiomas removed from the same patient:case report. Neurosurgery 1989; 25:447-50
  • 17. Terasaki KK, Zee CS. Evolution of central necrosis in a meningioma: CT and MR features. J Comput Assist Tomogr 1990; 14:464-6.
  • 18. Tokgoz N, Oner YA, Kaymaz M, Ucar M, Yılmaz G, Tali TE. Primary intraosseous meningioma: CT and MRI appearance. AJNR Am J Neuroradiol 2005; 26:2053-6.
  • 19. Servo A, Porras M, Jaaskelainen J, Paetau A, Haltia M. Computed tomography and angiography do not reliably discriminate malignant meningiomas from benign ones. Neuroradiology 1990; 32:94-7.
  • 20. Sato M, Matsumoto M, Kodama N. Meningeal enhancement surrounding meningiomas on Gd-DTPA MRI. Fukushima J Med Sci 1998; 44:1-11.
  • 21. Cesani F, Ernst R, Storey G, Villanueva-Meyer J. Multicentric meningioma evaluation withTc-99m MIBI SPECT, CT, and MRI. Clin Nucl Med 1995; 20:557-8.
  • 22. Nakasu S, Nakasu Y, Matsumura K, Matsuda M, Handa J. Interface between the meningioma and the brainonmagneticresonanceimaging. Surg Neurol 1990: 33;105-16.
  • 23. Gelabert-Gonzalez M, Leira-Muino R, FernandezVilla JM, Iglesias-Pais M. Multiple intracranial meningiomas. Rev Neurol 2003: 37; 717-22

Radiologic Findings of Multiple Meningiomas

Year 2006, Volume: 7 Issue: 3, 35 - 38, 01.12.2006

Abstract

The objective of this study is to investigate the Magnetic Resonance Imaging (MRI) and Computerized Tomography (CT) characteristics of multiple meningiomas (MM) which are rarely seen except with Recklinghausen disease. Seven female patients (average age: 49.28 years) with MM who have no family history of Recklinghausen disease are included in this study. All patients were scanned with MRI and one patient was also scanned with CT. Localization, intensity, contrast pattern (dural enhancement), and invasion characteristics were analyzed.Localizations of the tumors were as follows: 4 lesions in convexity, 3 lesions in parasagittal, 1 lesion in olfactorial groove, 1 lesion in tentorium and 1 lesion in sellar region. Multiple tumors were hypo intense in T1 weighted images, hyper intense in T2 weighted images and homogen contrast pattern (dural tail) in all cases. CT characteristics were similar to MRI. Meningiomas are the most common extra axial brain tumors which arise from the durameter and rarely seen in multiples except in Recklinghausen disease. Pathogenesis for multiplicity is largely unknown. Because they are mostly seen in females, as ours role of hormonal factors are speculated.

References

  • 1. Domenicucci M, Santoro A, D'Osvaldo DH, Delfini R, Cantore GP, Guidetti B. Multiple intracranial meningiomas. J Neurosurg 1989; 70:41-4
  • 2. Nasher HC, Grote W, Lohr E, Gerhardt L. Multiple meningiomas. Clinical and computer tomographic observations. Neuroradiology 1981; 21:259-63
  • 3. Spallone A, Neroni M, Giuffre R. Multiple skull base meningioma: case report. Surg Neurol 1999; 51:274- 80.
  • 4. Butti G, Assietti R, Casalone R, Paoletti P. Multiple meningiomas: a clinical, surgical, and cytogenetic analysis. Surg Neurol 1989;31:255-60.
  • 5. Locatelli D, Bottoni A, Uggetti C, Gozzoli L. Multiple meningiomas evaluated by computed tomography. Neurochirurgia (Stuttg) 1987; 30:8-10.
  • 6. Sheehy JP, Crockard HA. Multiple meningiomas: a long-term review. J Neurosurg 1983; 59:1-5.
  • 7. Borovich B, Doron Y, Braun J, et al. The incidence of multiple meningiomas--do solitary meningiomas exist?Acta Neurochir (Wien) 1988; 90:15-22.
  • 8. Anfimow J, Blumenau L. Ein Fall: multipler Geschwulste in der Schadelhöhle. Neurol Zentralbl 1889; 8:585
  • 9. Cushing H, Eisenhardt L: Meningiomas: their classification,regional behavior , life history and surgical end results, NewYork: Hafner, 1938, reprinted 1969: 224 249
  • 10. Basso AJ, Carrizo A. Sphenoid ridge meningiomas: Schmidek HH. Meningiomas and their surgical management. Philadelphia: WB Saunders, 1991:242- 259
  • 11. Stein ME, Druemea K, Guilbord JN, Kuten A. Lateagressive meningioma following prophlactic cranial irradiation for acute lymphoblastic leukaemia. Br J Radiol 1995; 68:1123-25
  • 12. Desai R, Bruce J. Meningiomas of the cranial base. J Neuro-Oncol 1994; 20:255-279
  • 13. KleinschmidtDeMasters BK, Lillihei KO. Radiation induced meningioma with a 63 year latency period: case report. J Neurosurg 1995; 82:487-488
  • 14. Lawrens E, Dixon M. Meningiomas imaging. Neurosurgery. McGraw-Hill. 1996: 855-872.
  • 15. Rosen CL. Meningiomas: the role of preoperative angiography and embolization. Neurosurg Focus 2003;15:1
  • 16. Kandel E, Sungurov E, Morgunov M. Cerebral and two spinal meningiomas removed from the same patient:case report. Neurosurgery 1989; 25:447-50
  • 17. Terasaki KK, Zee CS. Evolution of central necrosis in a meningioma: CT and MR features. J Comput Assist Tomogr 1990; 14:464-6.
  • 18. Tokgoz N, Oner YA, Kaymaz M, Ucar M, Yılmaz G, Tali TE. Primary intraosseous meningioma: CT and MRI appearance. AJNR Am J Neuroradiol 2005; 26:2053-6.
  • 19. Servo A, Porras M, Jaaskelainen J, Paetau A, Haltia M. Computed tomography and angiography do not reliably discriminate malignant meningiomas from benign ones. Neuroradiology 1990; 32:94-7.
  • 20. Sato M, Matsumoto M, Kodama N. Meningeal enhancement surrounding meningiomas on Gd-DTPA MRI. Fukushima J Med Sci 1998; 44:1-11.
  • 21. Cesani F, Ernst R, Storey G, Villanueva-Meyer J. Multicentric meningioma evaluation withTc-99m MIBI SPECT, CT, and MRI. Clin Nucl Med 1995; 20:557-8.
  • 22. Nakasu S, Nakasu Y, Matsumura K, Matsuda M, Handa J. Interface between the meningioma and the brainonmagneticresonanceimaging. Surg Neurol 1990: 33;105-16.
  • 23. Gelabert-Gonzalez M, Leira-Muino R, FernandezVilla JM, Iglesias-Pais M. Multiple intracranial meningiomas. Rev Neurol 2003: 37; 717-22
There are 23 citations in total.

Details

Other ID JA54EV53MN
Journal Section Case Report
Authors

Atilla Arslanoğlu This is me

Fuat Torun This is me

Bayram Çırak This is me

Publication Date December 1, 2006
Published in Issue Year 2006 Volume: 7 Issue: 3

Cite

EndNote Arslanoğlu A, Torun F, Çırak B (December 1, 2006) Radiologic Findings of Multiple Meningiomas. Meandros Medical And Dental Journal 7 3 35–38.