LENF NODU METASTAZI YAPAN BİR ADRENAL GANGLİONÖROM: OLGU SUNUMU

Year 2009, Volume: 10 Issue: 3, 47 - 49, 01.12.2009

Canten Tataroglu Füruzan Kaçar Döger Zeliha Çetın Serdar Özbas Hakan Erpek

Abstract

Ganglionöroma sempatik sinir sisteminin iyi diferansiye bir tümörüdür. Adrenal bezde nadiren görülür. En sıkgörülen tutulum yerleri posterior mediasten ve retroperitondur. Bu tümörler benign olmasına karşın nadirenbölgesel lenf nodlarına metastaz yaparlar. Genellikle klinik olarak bulgu vermezler ve başka sebepler için yapılanaraştırmalarda rastlantı sonucu saptanırlar. Histopatoloji, ganglionöroma tanısını koyma ve ganglionöroblastomile nöroblastom ayırıcı tanısını koymada en önemli basamaktır. Burada sol adrenalde ganglionöroma saptananerişkin bir hasta sunulmaktadır. Histopatolojik bakıda adrenalde matür ganglion hücreleri ve Schwannianstromadan oluşan tümöral lezyon izlendi. Paraaortik lenf nodlarında benzer tümör dokusu saptandı. Adrenalbezde ganglionöroma nadir görülür ve operasyon öncesinde tanı koymak çok zordur. Histopatolojik incelemetanı koymada en önemli basamaktır

Keywords

Ganglionörom, adrenal, metastaz

Adrenal Ganglioneuroma with Lymph Node Metastasis: A Case Report

Abstract

Ganglioneuroma is a well differentiated neoplasia of sympathetic nervous system. It is rare in the adrenal gland. The most common sites of involvement are the posterior mediastinum and retroperitoneum. These tumors though benign, can very rarely metastasize to regional lymph nodes. They are usually clinically silent and detected during exploration of other unrelated conditions. Histopathology is the only tool to diagnose ganglioneuroma and to differentiate it from ganglioneuroblastoma and neuroblastoma.We present an adult case with ganglioneuroma in her left adrenal. Histopathological examination showed that the tumoral lesion was a ganglioneuroma composed of both mature ganglion cells and Schwannian stroma arising in the adrenal gland. The paraaortic lymph node showed the same tumoral tissue. In conclusion, ganglioneuroma occurs rarely in adrenal gland and pre-operative diagnosis is difficult. Histopathological examination is the crucial step of diagnosis.

Keywords

Ganglioneuroma, adrenal, metastasis

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