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ALT SOLUNUM YOLU ENFEKSİYONLARI VE ÜST ÜRİNER SİSTEM ENFEKSİYONLARINDA TROMBOSİTOZ ORANLARI VE DEĞERLENDİRİLMESİ

Year 2011, Volume: 12 Issue: 2, 1 - 3, 01.08.2011

Abstract

AMAÇ:Alt solunum yolu enfeksiyonları ve üst üriner sistem enfeksiyonlarında trombositoz oranlarınınçıkarılması ve değerlendirilmesi amaçlanmıştır.GEREÇ VE YÖNTEM:Bu çalışmada “GATA Haydarpaşa Eğitim Hastanesi Çocuk Kliniği'nde” 1 Ocak 20061 Ocak 2009 yılları arasında yatırılarak tedavi verilen 20 alt solunum yolu enfeksiyonu (ASYE) ve 22 üst ürinersistem enfeksiyonu (ÜÜSE) tanısı alan hastanın dosyaları retrospektif olarak incelendi. Reaktif trombositoz,genel olarak kabul gören trombosit sayısının 500.000/mm üzeri olması kabul edildi. İstatistiksel veriler SPSS13.0 ile değerlendirildi.BULGULAR:Çalışmamızda trombositoz tanı anında üst üriner sistem enfeksiyonlarında daha fazla bulundu(ASYE %25, ÜÜSE %36). Üst üriner sistem enfeksiyonlarında en sık üreyen mikroorganizma Escherichia coli(n:12 %54) olarak tespit edildi.SONUÇ:Çalışmamızda, alt solunum yolu enfeksiyonu ve üst üriner sistem enfeksiyonunda tanı anında görülenreaktif trombositoz ile hastalık şiddeti karşılaştırılmış, arasında istatistiksel olarak anlamlı bir ilişkibulunamamıştır

References

  • 1. Schafer AI. Thrombocytosis and thrombocytemia. Blood Rev 2001;15:159-66.
  • 2. Hollen CW, Henthorn J, Koziol JA, Burstein SA. Elevated serum interleukin-6 levels in patients with reactive thrombocytosis. Br J Haematol 1991;79:286- 90.
  • 3. Haznedaroğlu IC, Ertenli I, Ozcebe OI, et al. Megakaryocyte- related interleukins in reactive thrombocytosis versus autonomous thrombocthemia. Acta Haematol 1996;95:107-11.
  • 4. Dan K, Gomi S, Inokuchi K, et al. Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis: mechanism of reactive thrombocytosis.Acta Haematol 1995;93:67-72.
  • 5. Dame C, Sutor AH. Primary and secondary thrombocytosis in childhood. Br J Haematol 2005;129:165-77.
  • 6. Taksin AL, Couedic JP, Dusanter-Fourt I, et al. Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L. Blood 1999;93:125-39.
  • 7. Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-9.
  • 8. Eliot MA, Pardanani A, Lasho TL, Schwager SM, Tefferi A. Thrombosis in myelofibrosis: prior thrombosis is the only predictive factor and most venous events are provoked. Haematologica 2010;95:1788-91.
  • 9. Heits F, Stahl M, Ludwig D, Stange EF, Jelkmann W. Elevated serum thrombopoietin and interleukin-6 concentrations in thrombocytosis associated with inflammatory bowel disease. J Interferon Cytokine Res 1999;19:757-60.
  • 10. Vora AJ, Lilleyman JS. Secondary thrombocytosis. Arch Dis Child 1993;68:88-90.
  • 11. Chan KW, Kaikov Y, Wadsworth LD. Thrombocytosis in childhood: a survey of 94 patients. Pediatrics 1989;84:1064-7.
  • 12. Yohannan MD, Higgy KE, al-Mashhadani SA, Santhosh-Kumar CR. Thrombocytosis. Etiologic analysis of 663 patients. Clin Pediatr 1994;33:340-3.
  • 13. Catal F,Bavbek N, Bayrak O, et al. Platelet paramaters in children with upper urinary tract infection: Is there a specific response? Renal Failure 2008;30:377-81.
  • 14. Garoufi A, Voutsioti K, Tsapra H, Karpathios T, Zeis PM. Reactive thrombocytosis in children with upper urinary tract infections.Acta Peadiatr 2001;90:448-9.

Evaluation of the Rate of Thrombocytosis in Lower Respiratory Tract and Upper Urinary System Infections

Year 2011, Volume: 12 Issue: 2, 1 - 3, 01.08.2011

Abstract

To evaluate the rates of thrombocytosis in lower respiratory tract (LRTI) and upper urinary
system infections (UUSI).
In this study, rates of thrombocytosis were evaluated in patients hospitalized
and treated with the diagnosis of LRTI (n=20) or UUSI (n=22) in “GATA Haydarpasa Teaching Hospital,
Department of Pediatrics” between 2006-2009, retrospectively. Reactive thrombocytosis is defined as the
platelet count over 500.000/mm . Statistical analysis was performed by SPSS for Windows version 13.0. p≤0.05
was accepted as statistically significant.
Thrombocytosis was found to be higher in the UUSI (%36) at the time of the diagnosis compared to
the LRTI group (25%). The most common microorganism identified in the UUSI was Escherichia coli (n=12,
54%).
There was no significant relationship between the reactive thrombocytosis observed at the
time of the diagnosis and the severity of the disease in the LRTI and the UUSI

References

  • 1. Schafer AI. Thrombocytosis and thrombocytemia. Blood Rev 2001;15:159-66.
  • 2. Hollen CW, Henthorn J, Koziol JA, Burstein SA. Elevated serum interleukin-6 levels in patients with reactive thrombocytosis. Br J Haematol 1991;79:286- 90.
  • 3. Haznedaroğlu IC, Ertenli I, Ozcebe OI, et al. Megakaryocyte- related interleukins in reactive thrombocytosis versus autonomous thrombocthemia. Acta Haematol 1996;95:107-11.
  • 4. Dan K, Gomi S, Inokuchi K, et al. Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis: mechanism of reactive thrombocytosis.Acta Haematol 1995;93:67-72.
  • 5. Dame C, Sutor AH. Primary and secondary thrombocytosis in childhood. Br J Haematol 2005;129:165-77.
  • 6. Taksin AL, Couedic JP, Dusanter-Fourt I, et al. Autonomous megakaryocyte growth in essential thrombocythemia and idiopathic myelofibrosis is not related to a c-mpl mutation or to an autocrine stimulation by Mpl-L. Blood 1999;93:125-39.
  • 7. Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-9.
  • 8. Eliot MA, Pardanani A, Lasho TL, Schwager SM, Tefferi A. Thrombosis in myelofibrosis: prior thrombosis is the only predictive factor and most venous events are provoked. Haematologica 2010;95:1788-91.
  • 9. Heits F, Stahl M, Ludwig D, Stange EF, Jelkmann W. Elevated serum thrombopoietin and interleukin-6 concentrations in thrombocytosis associated with inflammatory bowel disease. J Interferon Cytokine Res 1999;19:757-60.
  • 10. Vora AJ, Lilleyman JS. Secondary thrombocytosis. Arch Dis Child 1993;68:88-90.
  • 11. Chan KW, Kaikov Y, Wadsworth LD. Thrombocytosis in childhood: a survey of 94 patients. Pediatrics 1989;84:1064-7.
  • 12. Yohannan MD, Higgy KE, al-Mashhadani SA, Santhosh-Kumar CR. Thrombocytosis. Etiologic analysis of 663 patients. Clin Pediatr 1994;33:340-3.
  • 13. Catal F,Bavbek N, Bayrak O, et al. Platelet paramaters in children with upper urinary tract infection: Is there a specific response? Renal Failure 2008;30:377-81.
  • 14. Garoufi A, Voutsioti K, Tsapra H, Karpathios T, Zeis PM. Reactive thrombocytosis in children with upper urinary tract infections.Acta Peadiatr 2001;90:448-9.
There are 14 citations in total.

Details

Other ID JA39CP77FR
Journal Section Research Article
Authors

Onur Güngör This is me

Cihan Meral This is me

Ferhan Karademir This is me

Abdullah Barış Akcan This is me

Seçil Aydınöz This is me

Mustafa Kul This is me

Selami Süleymanoğlu This is me

Publication Date August 1, 2011
Published in Issue Year 2011 Volume: 12 Issue: 2

Cite

EndNote Güngör O, Meral C, Karademir F, Akcan AB, Aydınöz S, Kul M, Süleymanoğlu S (August 1, 2011) Evaluation of the Rate of Thrombocytosis in Lower Respiratory Tract and Upper Urinary System Infections. Meandros Medical And Dental Journal 12 2 1–3.