Genotypic structure of four cattle breeds raised in Turkey by loci related to several diseases

Year 2022, Volume: 35 Issue: 1, 39 - 45, 01.04.2022

Ferit Karayel Taki Karslı

https://doi.org/10.29136/mediterranean.995382

Abstract

This study aims to reveal the genotypic structure of four cattle breeds; Holstein (HS), Turkish Grey Steppe (TGS), Anatolian Black (AB) and East Anatolian Red (EAR), raised in Turkey in terms of CD14, MBL, ITGB6, SLC11A1 and TLR2 genes and to evaluate their usefulness in Marker Assisted Selection (MAS). It also assesses whether the loci associated with resistance to diseases are suitable for phylogenetic analysis. Desired alleles and/or genotypes were detected in native Turkish cattle breeds at different frequencies in terms of polymorphisms of CD14, MBL, ITGB6, SLC11A1 and TLR2 genes which were previously reported to be associated with mastitis, foot-and-mouth disease and tuberculosis. These variations offer opportunities to improve selection strategies against diseases in the future. These results preliminary indicate that associated studies between these variations and disease resistance in native Turkish cattle breeds should be conducted. On the other hand, phylogenetic tree constructed based on genetic distance clearly separated native Turkish cattle breeds from HS breed. The gene regions related to diseases can be used to distinguish native cattle breeds from exotic ones.

Keywords

ARMS-PCR, Candidate genes, Indigenous population, Microsatellite, PCR-RFLP

Supporting Institution

The Scientific Research Projects Coordination Unit of Akdeniz University

Project Number

FYL-2017-2355

Thanks

This research was financially supported by The Scientific Research Projects Coordination Unit of Akdeniz University with the project number of FYL-2017-2355.

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