Production of antibacterial polyvinylpyrrolidone nanofibers containing silver nanoparticles via electrospinning method

Year 2019, Volume: 7 Issue: 1, 13 - 23, 18.06.2019

Hava Çavuşoğlu Vatansever , Ayşegül Ersoy Meriçboyu

Abstract

Since polymeric nanofibers find extensive
usage in medical applications, the risks associated with bacterial
contamination must be taken into account. In this study, the production of
antibacterial polyvinylpyrrolidone (PVP) nanofibers containing silver nanoparticles
(AgNPs) was achieved. For this production AgNPs with the average diameters ranging from 5.69 nm to 14.83
nm were synthesized and characterized firstly. The properties of the nanofibers
produced via electrospinning method were investigated by means of scanning
electron microscopy (SEM) and X-ray diffraction (XRD) techniques. The effect of AgNPs on the conductivity of
electrospinning solutions were investigated. The stability of nanofiber
mats were determined to show the crosslinking efficiency. Finally,
antimicrobial tests against three types of microorganisms (E. coli, S. aureus and A.
niger) were carried out according to zone
of inhibition method. Antimicrobial test results proved that nanofibers
containing AgNPs show inhibition against E.coli
and S. aureus, while neat nanofibers
not. Additionally, any antifungal activity was not observed against A. niger.

Keywords

Silver nanoparticles, polyvinylpyrrolidone, electrospinning, nanofibers

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