Üriner Taş Hastalığı Olan Hastalarda Malign Aritmi Riskinin Elektrokardiyografi Parametreleri ile Değerlendirilmesi

Year 2024, , 129 - 134, 30.08.2024

Hilal Hocagil , Abdullah Cüneyt Hocagil , Tuğba Akkaya Hocagil

https://doi.org/10.29058/mjwbs.1397031

Abstract

Amaç: Yaşam boyu görülme sıklığı %10-15 olan ve 10 yıl içinde %50'ye varan nüks oranıyla üriner sistem taş hastalığı önemli bir komorbidite nedenidir. Son zamanlarda, üriner sistem taş hastalığının sadece böbrek taşı gelişimi ile sınırlı olmadığı, aynı zamanda kalp-damar hastalıkları ve diğer çeşitli hastalıklarla da bağlantılı olduğu yaygın olarak kabul edilmektedir. Malign aritmiler (ani kalp ölümü ve ventriküler aritmiler) koroner arter hastalığının sonuçlarıdır. Üriner sistem taş hastalığının koroner arter hastalığı için risk faktörü olduğunu gösteren çok sayıda çalışmaya rağmen bu hasta grubunda herhangi bir elektrokardiyografik parametre değerlendirilmemiştir.
Bu prospektif gözlemsel çalışma, üriner taş hastalığı olan hastalarda malign aritmiler için risk göstergesi olan ventriküler repolarizasyon parametrelerini elektrokardiyografi kullanarak değerlendirmeyi amaçlamaktadır.
Gereç ve Yöntem: Çalışmaya üriner sistem taşı hastalığı tanısı alan hastalar ve sağlıklı gönüllüler dahil edildi. Tüm hastalara 12 derivasyonlu elektrokardiyografi yapıldı. Elektrokardiyografiler QTc aralığı, QTc dağılımı, T tepe-uç aralığı ve Tp-e/QTc açısından değerlendirilerek kontrol grubuyla karşılaştırıldı.
Bulgular: Hasta ve kontrol grupları arasında QTc aralığı, QTc dağılımı, T tepe-uç aralığı ve Tp-e/QTc parametreleri karşılaştırıldığında istatistiksel olarak anlamlı bir fark bulunamadı.
Sonuç: Mevcut bilginin aksine bu çalışma, üriner taş hastalığı olan hastalarda malign aritmilerin normal popülasyondan anlamlı derecede farklı olmadığını buldu.

Keywords

Elektrokardiyografi parametreleri, Ventriküler aritmi riski, Ani kalp ölümü riski, Üriner taş hastalığı, Malign aritmi

Evaluation of the Risk of Malignant Arrhythmia Through Electrocardiography Parameters in Patients with Urinary Stone Disease

Abstract

Introduction: With a lifetime frequency of 10-15% and a recurrence rate of up to 50% within 10 years, urinary stone disease is a major cause of comorbidity. Recently, it has become widely recognized that urinary system stone disease is not only limited to kidney stone development but is also linked to cardiovascular disease and various other illnesses. Malignant arrhythmias (sudden cardiac death and ventricular arrhythmias) are consequences of coronary artery disease. Despite numerous studies demonstrating that urinary system stone disease is a risk factor for coronary artery disease, no electrocardiographic parameters have been evaluated in this patient group
This prospective observational study aims to assess ventricular repolarization parameters using electrocardiography, which are risk indicators for malignant arrhythmias in patients with urinary stones disease.
Materials and Methods The study included patients diagnosed with urinary stone disease and healthy volunteers. All patients underwent 12-lead electrocardiography. The electrocardiographys were evaluated for QTc interval, QTc dispersion, T peak-end interval, and Tp-e/QTc, and compared with the control group.
Results: When comparing the QTc interval, QTc dispersion, T peak-end interval, and Tp-e/QTc parameters between the patient and control groups, no statistically significant differences were found.
Conclusion: Contrary to existing knowledge, this study found that malignant arrhythmias in patients with urinary stone disease were not significantly different from the normal population.

Keywords

Electrocardiography parameters, Risk of ventricular arrhythmias, Risk of sudden cardiac death, Urinary stone disease, Malignant arrhythmia

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