A Comparison Between Modified Radical Mastectomy and Breast-Conserving Surgery Concerning the Quality of Life in Patients with Breast Cancer Under 50 Years of Age

Year 2021, , 63 - 67, 03.04.2021

Özlem Elmas Güldeniz Karadeniz Çakmak , Bekir Hakan Bakkal

https://doi.org/10.29058/mjwbs.804830

Cited By: 3

Abstract

surgery (BCS) to those having undergone modified radical mastectomy (MRM).
Material and Methods: Forty-four BCS and 27 MRM patients have been included in this retrospective
study. All patients have completed adjuvant chemotherapies and radiation therapies. MRM patients
who received breast reconstruction surgery afterwards, patients who experienced local or distant organ
relapse, or patients over fifty years old have been excluded. Each patient’s quality of life has been
evaluated using the Short Form 36 (SF-36), 6 months after the completion of their treatment.
Results: Between BCS and MRM groups, no significant difference of age, height, weight and body
mass index was observed. While the BCS group yielded better results from the SF-36 subscales, i.e.
physical functioning, physical role functioning, emotional role functioning, social role functioning, bodily
pain, and general health perceptions, the only measures illustrating a significant difference were vitality
and mental health, in comparison of BCS with MRM group (p= 0.043 and p= 0.023, respectively).
Conclusion: In the treatment of breast cancer, enhancing patients’ quality of life is just as essential as
improving survivals. Our research demonstrates higher quality of life in BCS patients, highlighting the
statistical difference of the vitality and mental health subscales of the SF-36, compared with the MRM
group.

Keywords

Breast cancer, Quality of life, Mastectomy, Breast-conserving surgery

Supporting Institution

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Project Number

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Thanks

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Elli Yaş Altı Meme Kanseri Hastalarında Modifiye Radikal Mastektomi ve Meme Koruyucu Cerrahinin Yaşam Kalitesi Açısından Karşılaştırılması

Abstract

Amaç: Meme koruyucu cerrahi (MKC) ve modifiye radikal mastektomi (MRM) uygulanmış meme
kanserli hastaların yaşam kalitelerinin karşılaştırılması.
Gereç ve Yöntemler: Kırk dört adet MKC ve 27 adet MRM uygulanmış meme kanserli kadın hasta
bu retrospektif çalışmaya dahil edilmiştir. Tüm hastalar adjuvan kemoterapi ve radyoterapilerini
tamamlamıştır. MRM sonrası meme rekonstrüksiyonu yapılanlar, lokal ya da uzak organda tekrarlama
gelişenler ve elli yaşın üstünde olanlar çalışmadan çıkarılmıştır. Tüm tedavilerin tamamlanmasından 6
ay sonra hastaların yaşam kalitesi Kısa Form 36 (SF-36) ile değerlendirilmiştir.
Bulgular: MKC ve MRM grupları arasında yaş, boy, ağırlık ve vücut kitle indeksi açısından anlamlı
fark yoktu. SF-36 ölçeklerinden fiziksel fonksiyon, fiziksel rol güçlüğü, duygusal rol güçlüğü, sosyal rol güçlüğü, ağrı ve genel sağlık algısı ölçeklerinde MKC grubunda MRM grubuna oranla daha iyi sonuçlar çıkmasına rağmen anlamlı fark bulunmazken, sadece vitalite ve ruhsal sağlık ölçeklerinde MKC grubunun değerleri MRM grubunun değerlerinden istatistiksel anlamda daha iyi bulundu (sırasıyla p= 0.043 ve p= 0.023).
Sonuç: Meme kanseri tedavisinde hastaların yaşam kalitesinin artırılması sağkalımı uzatmak kadar önemlidir. Çalışmamızda MKC hastalarında daha yüksek yaşam kalitesi olduğu gösterilmiştir, özellikle SF-36 ölçeklerinden vitalite ve ruhsal sağlık, MRM grubuna göre istatistiki anlamlı olacak şekilde daha iyi bulunmuştur.

Keywords

Meme kanseri, Yaşam kalitesi, Mastektomi, Meme koruyucu cerrahi

Project Number

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References

• 1. Statistics at www.cancer.org. Accessed Jan 25, 2019.
• 2. Galway K, Black A, Cantwell M, Cardwell CR, Mills M, Donnelly M. Psychosocial interventions to improve quality of life and emotional well-being for recently diagnosed cancer patients. Cochrane Database Syst Rev 2012;11:CD007064.
• 3. Pinar R. Reliability and construct validity of the SF-36 in Turkish cancer patients. Qual Life Res 2005;14:259-264.
• 4. Bulak H. Surgical management of breast carcinoma. Turkiye Klinikleri J Med Sci 1999;19:352-357.
• 5. Elmas Ö, Karadeniz Çakmak G, Bakkal BH. A comparison between breast-conserving surgery and modified radical mastectomy concerning the female sexual function in breast cancer patients under 50 years of age. Turk J Oncol 2020;35:26-30.
• 6. Cardoso MJ, Cardoso J, Santos AC, Vrieling C, Christie D, Liljegren G, Azevedo I, Johansen J, Rosa J, Amaral N, Saaristo R, Sacchini V, Barros H, Oliveira MC. Factors determining esthetic outcome after breast cancer conservative treatment. Breast J 2007;13:140-146.
• 7. Wang HT, Barone CM, Steigelman MB, Kahlenberg M, Rousseau D, Berger J, Daum A, Ortegon DP. Aesthetic outcomes in breast conservation therapy. Aesthet Surg J 2008;28:165-170.
• 8. Ozmen T, Polat AV, Kamali Polat A, Bonaventura M, Johnson R, Soran A. Factors affecting cosmesis after breast conserving surgery without oncoplastic techniques in an experienced comprehensive breast center. Surgeon 2015;13:139-144.
• 9. Ganz PA, Schag AC, Lee JJ, Polinsky ML, Tan SJ. Breast conservation versus mastectomy. Is there a difference in psychological adjustment or quality of life in the year after surgery? Cancer 1992;69:1729-1738.
• 10. Engel J, Kerr J, Schlesinger-Raab A, Sauer H, Hölzel D. Quality of life following breast-conserving therapy or mastectomy: Results of a 5-year prospective study. Breast J 2004;10:223- 231.
• 11. Arndt V, Stegmaier C, Ziegler H, Brenner H. Quality of life over 5 years in women with breast cancer after breast-conserving therapy versus mastectomy: A population-based study. J Cancer Res Clin Oncol 2008;134:1311-1318.
• 12. Shimozuma K, Sonoo H, Ichihara K, Miyake K, Kurebayashi J, Ota K, Kiyono T. The impacts of breast conserving treatment and mastectomy on the quality of life in early-stage breast cancer patients. Breast Cancer 1995;2:35-43.
• 13. Kement M, Gezen C, Aşik A, Karaöz A, Öven Ustaali̇oğlu B, Bilici A, Mustafa Ö. Meme kanserli Türk kadınlarında meme koruyucu cerrahi ve modifiye radikal mastektomi; yaşam kalitesine yönelik ileriye dönük bir analiz. Turkiye Klinikleri J Med Sci 2011;31:1377-1384.
• 14. Zanapalioğlu Y, Atahan K, Gür S, Çökmez A, Tarcan E. Effect of breast conserving surgery in quality of life in breast cancer patients. J Breast Health 2009;5:152-156.
• 15. O’Connell RL, DiMicco R, Khabra K, O’Flynn EA, deSouza N, Roche N, Barry PA, Kirby AM, Rusby JE. Initial experience of the BREAST-Q breast-conserving therapy module. Breast Cancer Res Treat 2016;160:79-89.