Yaşlanmada Beyin Sağlığı ve B Vitamini

Year 2021, , 331 - 336, 25.12.2021

Ayse Hamamcıoglu , Eylül Karabaş

https://doi.org/10.29058/mjwbs.871573

Abstract

B vitaminleri suda çözünebilen vitaminler olup, önemli biyolojik rollere sahiptirler. Her B vitamini, anahtar
metabolik süreçler için kofaktördür veya gerekli birer öncüdür. Bilişsel işlevler; hafıza, öğrenme, uzamsal
yönelim, akıl yürütme, yargılama ve değerlendirmeyi içeren çeşitli beyin fonksiyonlarıdır. Bu işlevlerin
azalması, hafif kognitif bozukluk olarak başlayan ve demansa kadar giden ilerleyici bir durumdur. B
vitaminlerinin düşük düzeyde alınması sonucu kognitif bozukluk riskinin artması ve yaşlanmaya bağlı
hastalıklara katkıda bulunması tek karbon metabolizması ile ilişkilidir. Bu derlemede B vitaminlerini, tek
karbon metabolizmasını ve B vitaminlerinin yaşlanmada beyin sağlığı üzerindeki rolünü inceledik.

Keywords

B vitamini, tek karbon metabolizması, yaşlanma, beyin sağlığı

Brain Health and B Vitamins in Ageing

Abstract

B vitamins are water-soluble vitamins and have important biological roles. Each B vitamin is a cofactor
or essential precursor for key metabolic processes. Cognitive functions are various brain functions that
include memory, learning, spatial orientation, reasoning, judgment, and evaluation. The decrease in
these functions is a progressive condition that begins as mild cognitive impairment and progresses to
dementia. Low intake of B vitamins is associated with a one carbon metabolism, which increases the
risk of cognitive impairment and contributes to aging-related diseases. In this review, we examine B
vitamins, one carbon metabolism, and the role of B vitamins to aging brain.

Keywords

B Vitamins, one carbon metabolism, ageing, brain health

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