Report of Familial Mediterranean Fever with Repeating Localized Rash and Weakness

Year 2020, Volume: 4 Issue: 1, 34 - 37, 30.04.2020

Coşkun Ekemen , Ahmet Girgeç , Hakan Kardeş , Zühal Örnek

Abstract

Familial Mediterranean Fever (FMF), which is inherited as autosomal recessive, is characterized
by recurrent fever, rash, arthritis, arthralgia, and abdominal pain. The most important complication
of FMF, which can affect many systems, is amyloidosis development due to kidney involvement.
The main drug used in the treatment is colchicine. In this article, a case which arrived at the
pediatric clinic with recurrent unilateral localized ankle complaints of edema, erythema together
with rash and which, as a result of clinical and genetic tests, was diagnosed as FMF is examined.
Symptoms observed at the preliminary diagnosis such as recurrent fever, abdominal pain, arthritis
or arthralgia or isolated erysipelas should definitely remind pediatricians FMF. In this way, early
amyloidosis development and complications due to FMF will be prevented in children

Keywords

FMF, Familial Mediterranean Fever, Arthritis, Rash

Tekrarlayan Lokalize Döküntü ve Halsizlikle Başvuran Ailesel Akdeniz Ateşi Olgu Sunumu

Abstract

Otozomal resesif kalıtılan Ailesel Akdeniz Ateşi tekrarlayan ateş, döküntü, artrit, artralji, karın ağrısı
gibi klinik bulgularla karakterizedir. Birçok sistemi tutabilen FMF’nin en önemli komplikasyonu
böbrek tutulumuna bağlı amiloidoz gelişimidir. Tedavide kullanılan temel ilaç ise kolşisindir. Bu
makalede çocuk hastalıkları polikliniğine tekrarlayan tek taraflı lokalize ayak bileğinde ödem, kızarıklık
ve döküntü yakınmaları ile başvuran ve takibinde klinik ve genetik tetkikler sonucunda
FMF tanısı alan bir olgu sunulmuştur. Tekrarlayan ateş, karın ağrısı, artrit veya artralji ya da izole
erizipel benzeri döküntüsü olan çocuklarda FMF ön tanıda mutlaka akla gelmelidir. Bu sayede
çocuklarda erken amiloidoz gelişimi ve FMF’e bağlı komplikasyonlar da engellenmiş olacaktır

Keywords

FMF, ailesel akdeniz ateşi, artrit, döküntü

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