Onikomikoz ve Erektil Disfonksiyon: Ortak Etyoloji Birlikteliğe Neden Olur Mu?

Year 2021, Volume: 5 Issue: 2, 256 - 260, 29.05.2021

Özer Baran Aykut Aykaç Coskun Kaya Habibullah Aktaş

https://doi.org/10.29058/mjwbs.876669

Cited By: 1

Abstract

Amaç: Erektil Disfonksiyon (ED) ile Onikomikoz (OM) hastalığının birlikte görülme sıklığını saptamaya çalıştık.
Gereç ve Yöntem: Nisan 2019 – Nisan 2020 tarihleri arasında Karabük Üniversitesi Tıp Fakültesi Üroloji Polikliniği’ne ED şikâyeti ile başvuran erkek hastalara sosyodemografik form ve IIEF-5 formu doldurtuldu. ED saptanan hastalar çalışmaya dahil edildi. Tüm erkekler ED ciddiyetine göre hafif, orta, ciddi olmak üzere üç gruba ayrıldı. Dermatoloji uzmanı (H.A.) erkeklerin ayak tırnaklarından örnek alıp OM mevcudiyetini araştırdı.
Bulgular: Çalışmaya kabul edilen 95 hastanın IIEF-5 skorlarına bakılarak 22’sinde (%23.1) hafif, 20’sinde (%21) orta ve 53’ünde (%55.9) ciddi düzeyde ED bulunduğu saptandı. Sigara kullanma öyküsü ciddi ED grubunda daha fazla idi (p <0.001). Toplam 32 (%33.7) hastada OM bulunduğu tespit edildi. Ancak, ED şiddeti ile OM mevcudiyeti arasında bir ilişki saptanmadı (p>0.114).
Sonuç: Erektil disfonksiyon ile OM hastalığı sıklıkla bir arada görülebilmektedir. Ancak ED şiddeti ile bir ilişkisi saptanmamıştır.

Keywords

onikomikozis, erektil disfonksiyon, etiyoloji

Onychomycosis and Erectile Dysfunction. Does Common Etiology Cause Togetherness?

Abstract

Background: We tried to determine the frequency of co-occurrence of erectile dysfunction (ED) and Onychomycosis (OM).
Material and Method: The sociodemographic form and IIEF-5 form were filled by the male patients who were admitted to the Urology Polyclinic of Karabük University Medical Faculty with the complaints of ED between April 2019 - April 2020. The patients with ED were included in the study. All the male patients were divided into three groups as mild, moderate and severe according to ED severity. The dermatologist (H.A) examined the presence of OM by taking samples from the toenails of the male patients.
Results: Looking at the IIEF-5 scores of 95 patients accepted to the study, it was found that 22 (23.1%) had mild, 20 (21%) moderate and 53 (55.9%) severe ED. Smoking history was higher in the severe ED group (p <0.001). It was found that a total of 32 (33.7%) patients had OM. However, there was no relationship between the severity of ED and the presence of OM (p> 0.114).
Conclusion: Erectile dysfunction and OM disease can often be seen together. However, no relationship was found with the severity of ED.

Keywords

onychomycosis, erectil disfunction, etiology

References

• 1. Gandaglia G, Briganti A, Jackson G, Kloner RA, Montorsi F, Montorsi P, Vlachopoulos C. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol. 2014; 65: 968–78.
• 2. Maas R, Schwedhelm E, Albsmeier J, Boger RH: The pathophysiology of erectile dysfunction related to endothelial dysfunction and mediators of vascular function. Vasc Med. 2002; 7: 213-5.
• 3. Sigurgeirsson B, Baran R. The prevalence of onychomycosis in the global population – A literature study. J Eur Acad Dermatol Venereol. 2014 Nov;28(11):1480-91.
• 4. Kampoli AM, Tousoulis D, Briasoulis A, Latsios G, Papageorgiou N, Stefanadis C. Potential pathogenic infl ammatory mechanisms of endothelial dysfunction induced by type 2 diabetes mellitus. Curr Pharm Des. 2011; 17: 4147–58.
• 5. Tousoulis D, Kampoli AM, Stefanadis C. Diabetes mellitus and vascular endothelial dysfunction: current perspectives. Curr Vasc Pharmacol. 2012; 10: 19–32.
• 6. Jude EB, Eleftheriadou I, Tentolouris N. Peripheral arterial disease in diabetes – a review. Diabet Med 2010; 27: 4–14.
• 7. Ferket BS, Spronk S, Colkesen EB, Hunink MG. Systematic review of guidelines on peripheral artery disease screening. Am J Med. 2012; 125: 198–208.
• 8. Gupta AK, Gupta MA, Summerbell RC, Cooper EA, Konnikov N, Albreski D, et al. The epidemiology of onychomycosis: possible role of smoking and peripheral arterial disease. J Eur Acad Dermatol Venereol. 2000; 14: 466–9.
• 9. Hotaling JM, Walsh TJ, Macleod LC, Heckbert S, Pocobelli G, Wessells H, et al. Erectile dysfunction is not independently associated with cardiovascular death: data from the vitamins and lifestyle (VITAL) study. J Sex Med. 2012; 9: 2104-10.
• 10. Nehra A, Jackson G, Miner M, Billups KL, Burnett AL, Buvat J, et al. The Princeton III consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc. 2012; 87:766-78.
• 11. Spessoto LC, Facio FN Jr, de Arruda JG, Arruda PF, Gatti M, Antoniassi TS, et al. Association of Hypertension With Erectile Function in Chronic Peripheral Arterial Insufficiency Patients. J Clin Med Res. 2016 Aug;8(8):582-4.
• 12. Giuliano F: New horizons in erectile and endothelial dysfunction research and therapies. Int J Impot Res. 2008; 20:2-8.
• 13. Fukunaga A, Washio K, Ogura K, Taguchi K, Chiyomaru K, Ohno Y, et al. Onychomycosis as a warning sign for peripheral arterial disease. Acta Derm Venereol. 2013; 93: 747 – 8.
• 14. Go AS, Mozaffarian D, Roger VL, Benjamin EJ, Berry JD, Borden WB, et al. Heart disease and stroke statistics—2013 update: a report from the American Heart Association. Circulation. 2013; 127: 6–245.
• 15. Dong JY, Zhang YH, Qin LQ. Erectile dysfunction and risk of cardiovascular disease: meta-analysis of prospective cohort studies. J Am Coll Cardiol. 2011; 58: 1378–85.
• 16- Kumagai H, Yoshikawa T, Myoenzono K, Kosaki K, Akazawa N, Asako ZM, et al. Sexual Function Is an Indicator of Central Arterial Stiffness and Arterial Stiffness Gradient in Japanese Adult Men. J Am Heart Assoc. 2018 May 5;7(10).
• 17. Montorsi P, Ravagnani PM, Galli S, Rotatori F, Veglia F, Briganti A, et al. Association between erectile dysfunction and coronary artery disease. Role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial. Eur Heart J. 2006; 27:2632-39.
• 18. Shin D, Pregenzer G, Gardin JM. Erectile dysfunction: a disease marker for cardiovascular disease. Cardiol Rev. 2011; 19: 5-11.
• 19. Gandaglia G, Briganti A, Jackson G, Kloner RA, Montorsi F, Montorsi P, Vlachopoulos C. A systematic review of the association between erectile dysfunction and cardiovascular disease. Eur Urol 2014; 65: 968-78.
• 20. Onalan O, Adar A, Keles H, Ertugrul G, Ozkan N, Aktas H et al. Onychomycosis is associated with subclinical atherosclerosis in patients with diabetes. Vasa. 2015 Jan; 44: 59-64.
• 21. Ozkan F, Ozturk P, Ozyurt K, İncı MF, Kalender AM, Bakan B et al. Frequency of peripheral arterial disease and venous insufficiency in toenail onychomycosis. J Dermatol. 2013; 40: 107-10.
• 22. Ermertcan AT, Temeltaş G. Dermatologic diseases and their effects on male sexual functions. J Dtsch Dermatol Ges. 2010; 8: 592-7.
• 23. Goulding JM, Price CL, Defty CL, Hulangamuwa CS, Bader E, Ahmed I. Erectile dysfunction in patients with psoriasis: increased prevalence, an unmet need, and a chance to intervene. Br J Dermatol. 2011; 164: 103–9.
• 24. Duarte GV, Calmon H, Radel G, de Fátima Paim de Oliveira M. Psoriasis and sexual dysfunction: links, risks, and management challenges. Psoriasis (Auckl). 2018; 8: 93-9.