Antipsikotikler ve Antidepresanlar Aort Diseksiyonlarının Oluşumunu veya Kronikleşmesini Etkileyebilir mi?

Year 2021, Volume: 5 Issue: 3, 497 - 500, 25.12.2021

Burak Can Depboylu , Buğra Harmandar , Kadir Arslan Serkan Yazman

https://doi.org/10.29058/mjwbs.894748

Abstract

Akut Stanford tip-A aort diseksiyonları(STAAD), aort rüptürü, ciddi aort kapak yetmezliği, perikardiyal
tamponad ve serebral ve/veya koroner malperfüzyon risklerini ortadan kaldırmak için acil cerrahi
gerektiren, hayatı tehdit edici hastalıklardır. Sadece küçük bir hasta alt grubu fark edilmez ve belirsiz
mekanizma ile kronikleşir. Bu hastalar genellikle geç semptomlar yüzünden veya tesadüfen teşhis edilir.
Kardiyopulmoner bypass ve bazen derin hipotermi ve sikülatuvar arrest gerektiren cerrahi teknikler,
önemli mortalite ve komplikasyonları olan ilk basamak tedavilerdir. Burada, antipsikotik ve antidepresan
tedavi alan ve total aortik ark replasmanı ile başarıyla onarılan tanısı tesadüfen konulmuş kronik STAAD
hastası sunulmuştur

Keywords

Kronik aort diseksiyonu, Kan basıncı, Antipsikotikler, Antidepresanlar, Cerrahi

Can Antipsychotics and Antidepressants Affect the Formation or Chronicization of Aortic Dissections?

Abstract

Acute Stanford type-A aortic dissections (STAAD) are life-threatening diseases which require
emergency surgery to eliminate risks of aortic rupture, severe aortic valve insufficiency, pericardial
tamponade and cerebral and/or coronary malperfusion. Only a small subset of patients go unnoticed
and become chronic with unclear mechanism. These patients are usually diagnosed thru late symptoms
or incidentally. Surgical techniques requiring cardiopulmonary bypass and sometimes deep hypothermia
and circulatory arrest are first-line treatments with considerable mortality and complications. Herein,
an incidentally diagnosed chronic STAAD patient who was receiving antipsychotic and antidepressant
treatment and successfully repaired with total aortic arch replacement was presented.

Keywords

Chronic aortic dissection, Blood pressure, Antipsychotics, Antidepressants, Surgery

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