Case Report
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COVID-19 Re-Enfekte Hastada Periorbital Herpes Zoster Duplex Bilateralis Birlikteliği

Year 2021, Volume: 5 Issue: 3, 501 - 504, 25.12.2021
https://doi.org/10.29058/mjwbs.956727

Abstract

Amaç: Varicella-zoster virüsü (VZV) bir insan nörotrofik virüsüdür ve Herpes Zoster (HZ), önceden
geçirilmiş bir suçiçeği enfeksiyonunu takiben VZV’nin dorsal kök gangliyonundaki latent durumundan
yeniden aktive olduğunda ortaya çıkan bir enfeksiyondur. COVID-19 enfeksiyonunda yaygın ürtiker,
suçiçeği benzeri papülo veziküler erüpsiyon, vaskülitik lezyonlar ve HZ gibi çeşitli deri bulgularına
rastlandığı da gözlenmiştir. Bitişik olmayan iki dermatom tutulduğunda, tek taraflı etkilenirse herpes
zoster duplex unilateralis; iki taraflı ise, bilateralis olarak adlandırılır.
Olgu: 39 yaşında kadın hasta, yüksek ateş, halsizlik, öksürük, nefes darlığı ve her iki göz kapağında
oluşan döküntüler nedeniyle kliniğimize başvurdu. Hastanın anamnezinden üç ay önce COVID-19
enfeksiyonu ve eşzamanlı olarak yüz felci geçirdiği öğrenildi. Dermatolojik muayenesi sonucunda iki
taraflı üst göz kapağında yer alan eritemli zeminde grupe veziküler lezyonların HZ duplex bilateralis
ile uyumlu olduğu düşünüldü. 14. Gün sonunda COVID-19 enfeksiyon bulgularının kaybolması ve deri
lezyonlarının tamamen iyileşmesi üzerine hasta taburcu edildi.
Sonuç: Olgumuz immunkompetan olmasına rağmen ikinci kez COVID-19 enfeksiyonu geçirirken üst
göz kapaklarında HZ duplex bilateralis tanısı alması nedeniyle dikkat çekicidir. COVID-19 enfeksiyonu
ile HZ dupleks bilateralis birlikteliği şimdiye kadar literatürde bildirilmemiştir. COVID -19 ile enfekte
hastalarda HZ enfeksiyonunun sıradışı tutulumlar ile ortaya çıkabileceği göz ardı edilmemelidir.

References

  • 1-Sachdeva M, Gianotti R, Shah M, et al. Cutaneous manifestations of COVID-19: Report of three cases and a review of literature. J Dermatol Sci 2020; 98: 75-81.
  • 2-Elsaie ML, Nada HA. Herpes zoster (shingles) complicating the course of COVID19 infection. J Dermatol Treat 2020; 12:1-3.
  • 3-Saati A, Al-Husayni F, Malibari AA, et al. Herpes zoster co-infection in an immunocompetent patient with COVID-19. Cureus 2020; 12: e8998.
  • 4-Tartari F, Spadotto A, Zengarini C, Zanoni R, et al. Herpes zoster in COVID-19-positive patients. International Journal of Dermatology; 2020; 59:1028-1029.
  • 5- I. Staikov, N. Neykov, B. Marinovic, et al. Herpes zoster as a systemic disease Clinics in Dermatology, 2014; 32:424–429.
  • 6- Jiang M, Guo Y, Luo Q, et al. T-cell subset counts in peripheral blood can be used as discriminatory biomarkers for diagnosis and severity prediction of Coronavirus Disease 2019. J Infect Dis. 2020;2 22:198–202.
  • 7- Lee SY, Choi YS, Yu HJ, Son SJ. A case of bilateral herprs zoster. Korean J Dermatol. 1994;32:1119–1122.
  • 8-Ferreira ACA de F. Romão TT. Macedo YS. et al. COVID-19 and herpes zoster co-infection presenting with trigeminal neuropathy. 2020. Eur J Neurol. 2020; 27:1748-1750.
  • 9- Cockburn DM, Douglas IS. Herpes zoster opthalmicus. Clin Exp Optom 2000; 83:59–64.
  • 10- Castronovo C, Nikkels AF. Chronic herpes zoster duplex bilateralis Acta Derm Venereol. 2012; 48-51.
  • 11- Zheng M, Gao Y, Wang G, et al Functional exhaustion of antiviral lymphocytes in COVID‐19 patients. Cell Mol Immunol 2020; 17: 533–535.
  • 12- McKay SL, Guo A, Pergam SA, et al. Herpes zoster risk in immunocompromised adults in the United States: a systematic review. Clin Infect Dis. 2020; 71:e125-e134.
  • 13- Wang F, Nie J, Wang H, et al. Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia. J Infect Dis. 2020; 221:1762–1769.
  • 14 - Elsaie, Mohamed L; Youssef, Eman A; Nada, Hesham A. Herpes zoster might be an indicator for latent COVID 19 infection. Dermatol Ther ; 2020; 33:e13666.

Co-Infection of Periorbital Herpes Zoster Duplex Bilateralis in COVID-19 Re-Infected Patient

Year 2021, Volume: 5 Issue: 3, 501 - 504, 25.12.2021
https://doi.org/10.29058/mjwbs.956727

Abstract

Aim: Varicella-zoster computer virus (VZV) is a human neurotrophic computer and Herpes Zoster
(HZ) is a retargeted selection from potential target in the dorsal root ganglion of a bred varicella VZV.
Urticaria, which becomes common when COVID-19 grows, has been observed where papule-vesicular
eruptions such as chicken pox and days appearing as HZ are observed. Unilateral herpes zoster duplex
unilateralis when in two non-adjacent dermatomes; If it is bilateral, it is called bilateral.
Case: A 39-year-old female patient was admitted to our clinic with high fever, weakness, cough,
shortness of breath and rash on both eyelids. It was learned from the patient’s anamnesis that he had
COVID-19 infection and simultaneous facial paralysis three months ago. As a result of the dermatological
examination, it was thought that grouped vesicular lesions on the erythematous background on
the bilateral upper eyelid were compatible with HZ duplex bilateralis. At the end of the 14th day, the
patient was discharged after the signs of COVID-19 infection disappeared and the skin lesions healed
completely.
Conclusion: Although our case was immunocompetent, it is noteworthy that she was diagnosed with HZ duplex bilateralis on the upper
eyelids while she was infected with COVID 19 for the second time. The coexistence of COVID 19 infection and HZ duplex bilateralis has
not been reported in the literature so far. It should not be ignored that HZ infection may occur with unusual involvements in patients infected
with COVID-19.

References

  • 1-Sachdeva M, Gianotti R, Shah M, et al. Cutaneous manifestations of COVID-19: Report of three cases and a review of literature. J Dermatol Sci 2020; 98: 75-81.
  • 2-Elsaie ML, Nada HA. Herpes zoster (shingles) complicating the course of COVID19 infection. J Dermatol Treat 2020; 12:1-3.
  • 3-Saati A, Al-Husayni F, Malibari AA, et al. Herpes zoster co-infection in an immunocompetent patient with COVID-19. Cureus 2020; 12: e8998.
  • 4-Tartari F, Spadotto A, Zengarini C, Zanoni R, et al. Herpes zoster in COVID-19-positive patients. International Journal of Dermatology; 2020; 59:1028-1029.
  • 5- I. Staikov, N. Neykov, B. Marinovic, et al. Herpes zoster as a systemic disease Clinics in Dermatology, 2014; 32:424–429.
  • 6- Jiang M, Guo Y, Luo Q, et al. T-cell subset counts in peripheral blood can be used as discriminatory biomarkers for diagnosis and severity prediction of Coronavirus Disease 2019. J Infect Dis. 2020;2 22:198–202.
  • 7- Lee SY, Choi YS, Yu HJ, Son SJ. A case of bilateral herprs zoster. Korean J Dermatol. 1994;32:1119–1122.
  • 8-Ferreira ACA de F. Romão TT. Macedo YS. et al. COVID-19 and herpes zoster co-infection presenting with trigeminal neuropathy. 2020. Eur J Neurol. 2020; 27:1748-1750.
  • 9- Cockburn DM, Douglas IS. Herpes zoster opthalmicus. Clin Exp Optom 2000; 83:59–64.
  • 10- Castronovo C, Nikkels AF. Chronic herpes zoster duplex bilateralis Acta Derm Venereol. 2012; 48-51.
  • 11- Zheng M, Gao Y, Wang G, et al Functional exhaustion of antiviral lymphocytes in COVID‐19 patients. Cell Mol Immunol 2020; 17: 533–535.
  • 12- McKay SL, Guo A, Pergam SA, et al. Herpes zoster risk in immunocompromised adults in the United States: a systematic review. Clin Infect Dis. 2020; 71:e125-e134.
  • 13- Wang F, Nie J, Wang H, et al. Characteristics of peripheral lymphocyte subset alteration in COVID-19 pneumonia. J Infect Dis. 2020; 221:1762–1769.
  • 14 - Elsaie, Mohamed L; Youssef, Eman A; Nada, Hesham A. Herpes zoster might be an indicator for latent COVID 19 infection. Dermatol Ther ; 2020; 33:e13666.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Case Report
Authors

Göktuğ Demirci 0000-0002-5079-4713

Gülşen Tükenmez Demirci 0000-0002-9646-0719

Publication Date December 25, 2021
Acceptance Date December 8, 2021
Published in Issue Year 2021 Volume: 5 Issue: 3

Cite

Vancouver Demirci G, Tükenmez Demirci G. COVID-19 Re-Enfekte Hastada Periorbital Herpes Zoster Duplex Bilateralis Birlikteliği. Med J West Black Sea. 2021;5(3):501-4.

Medical Journal of Western Black Sea is a scientific publication of Zonguldak Bulent Ecevit University Faculty of Medicine.

This is a refereed journal, which aims at achieving free knowledge to the national and international organizations and individuals related to medical sciences in publishedand electronic forms.

This journal is published three annually in April, August and December.
The publication language of the journal is Turkish and English.