Anjiografi Yapılan ve Normal Koroner Arterler Gözlenen Stabil Anjina Pektorisli Hastalarda Koroner Yavaş Akımın Prediktörü Olarak ABO Kan Grupları

Year 2024, Volume: 8 Issue: 3, 348 - 354, 30.12.2024

Uğur Köktürk , Talha Serin , Fatma Tuğçe Topuz , Berkay Işık , Ayşe Nur Eken , Abdülkadir Ataç , Nazende Altıntaş , Rabia Çağlardağ , Kübra Balık , Zeynep İsmihan Avşar , Esra Özgüler , İpek Naz Gündoğan

Abstract

Amaç: Çalışmada stabil anjina pektoris tanısıyla koroner anjıografi yapılan ve normal koroner arter bulunan hastalarda koroner yavaş
akımla ABO kan grupları arasındaki ilişkinin araştırılması amaçlanmıştır.
Gereç ve Yöntemler: Çalışmaya stabil anjina pektoris tanısıyla koroner anjiografi yapılan ve normal koroner arter saptanan 203 hasta
retrospektif olarak alınmıştır. Hastalar yavaş akım ve normal akım gözlenen olarak iki gruba ayrılmıştır. ABO kan grupları ve koroner yavaş
akım arasındaki ilişki incelenmiştir.
Bulgular: Yavaş akım gözlenen gruptaki hastalar kontrol grubuna göre daha ileri yaştaydı (p=0,049). Yavaş akım gözlenen grupta kontrol
grubuna göre anlamlı olarak 0 kan grubu, 0 olmayan kan gruplarına göre daha düşük gözlenmesine rağmen, A kan grubu, A olmayan
kan grubuna göre anlamlı olarak daha yüksek gözlenmiştir (sırasıyla p=0,024 karşı p=0,038). Çok değişkenli analiz, stabil anjina pektoris
ile başvuran koroner anjiyografi yapılan ve koroner arterleri normal olan hastalarda A kan grubunun, koroner yavaş akışın bağımsız bir
belirleyicisi olarak pozitif ilişkili olduğunu belirlemesine rağmen 0 kan grubunun ters ilişkili olduğunu gösterdi. (sırasıyla, OR: 2,226; 95%
CI:1,067-4,646; p=0,033, OR=0,836; %95CI=0,451-0,957; p=0,042).
Sonuç: Bu çalışma stabil anjina pektoris tanısı alıp koroner anjiografi yapılan ve normal koroner arter saptanan hastalarda koroner yavaş
akım ile ABO kan grupları arasında ilişki olabileceğini göstermiştir. Ek olarak, A kan grubunun bu hastalarda koroner yavaş akımın bağımsız
öngördürücüsü olduğunu tespit etmiştir.

Keywords

ABO kan grubu, stabil anjina pektoris, yavaş akım

Ethical Statement

Zonguldak Bülent Ecevit Üniversitesi Girişimsel Olmayan Klinik Araştırmalar Etik Kurulu’ndan onay alınmıştır (Tarih:20/03/2024, No:2024/06).

ABO Blood Groups as Predictors of Coronary Slow Flow in Patients with Stable Angina Pectoris Who Underwent Angiography and Observed Normal Coronary Arteries

Abstract

Aim: In this study, we aimed to investigate the relationship between coronary slow flow and ABO blood groups in patients who presented
with stable angina pectoris and underwent coronary angiography, and had normal coronary arteries.
Material and Methods: 203 patients who were diagnosed with stable angina pectoris and underwent coronary angiography and were found
to have normal coronary arteries were included in the study retrospectively. Patients were divided into two groups: those with slow flow and
those without. The relationship between ABO blood groups and coronary slow flow was examined.
Results: Patients in the slow flow group were older than the control group (p=0.049). Although the 0 blood group was observed to be
significantly lower than the non-0 blood groups in the slow flow group compared to the normal flow group, the A blood group was significantly
higher than the non-A blood group (p=0.024 vs p=0.038, respectively). Multivariate analysis determined that blood type A was positively
associated as an independent predictor of coronary slow flow in patients who underwent coronary angiography presenting with stable angina
pectoris and had normal coronary arteries, whereas blood group O was inversely associated. (OR:2.226; 95%CI:1.067-4.646; p=0.033,
OR=0.836; %95CI=0.451-0.957; p=0.042, respectively).
Conclusion: This study showed that there is a relationship between coronary slow flow and ABO blood groups in patients who were
diagnosed with stable angina pectoris and underwent coronary angiography and normal coronary arteries were detected. Additionally, it
found that blood type A was an independent predictor of coronary slow flow in these patients

Keywords

ABO blood group, stable angina pectoris, slow flow

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