Clinical Research
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Vajinal Doğum için Uygulanan Epidural Analjezinin Değerlendirilmesi: Bir Devlet Hastanesinin Retrospektif Analizi

Year 2024, Volume: 8 Issue: 3, 307 - 313, 30.12.2024

Abstract

Amaç: Epidural analjezi doğum ağrısı kontrolünde en çok uygulanan analjezi yöntemidir. Amacımız; epidural analjezinin anne-fetus ve
doğum eylemi üzerine etkisini araştırmaktır.
Gereç ve Yöntemler: 2017 yılında (Ocak- Aralık) arasında doğum için epidural analjezi uygulanan gebelerin dosyaları retrospektif olarak
incelendi. Gebelerin demografik verileri, hemodinamik parametreleri, doğum evrelerinin süreleri, sezeryana dönüş oranları, epidural öncesi
ve sonrası vizuel analog skala (VAS) değerleri, APGAR skoru, maternal ve fetal yan etkiler, gebelerin memnuniyeti değerlendirildi.
Bulgular: Ağrısız doğum analjezi protokolümüz ile VAS değerlerinin 2-3 olduğu , 153 gebeden sezaryana dönüş oranının %2 olduğu,
maternal yan etki olarak hipotansiyon % 3,9 oranında görüldüğü, gebe memnuniyet oranının ve tekrar epidural tercih etme oranının %85,6,
1. ve 5. dak. APGAR skorunun da 9-10 olduğu, olumsuz bir etkisi olmadığı görüldü.
Sonuç: Epidural analjezi; tecrübeli uygulayıcılarla kadın doğum doktoru ile işbirliği içerisinde multidisipliner yaklaşılması gereken bir
müdahaledir. Annenin yaşadığı ağrı ile beraber stresini de büyük oranda azaltarak doğumun konforunu da artıran bu yöntemi ağrısız vajinal
doğum için uygun tüm gebelere öneriyoruz.

Ethical Statement

Zonguldak bülent Ecevit Üniversitesi Girişimsel olmayan Etik kurul Başkalığınca 23/06/2021 toplantı tarıhlı ve 2021/12 toplantı karar numarsı ile etik krul ilkelerine uygunluğuna karar verilmiştir

References

  • 1. Wong CA. Epidural and spinal analgesia/anesthesia for labor and vaginal delivery. In: Chestnut’s Obstetric Anesthesia: Principles and Practice. 5th ed. Philadelphia, PA: Elsevier/Saunders; 2014:457-517
  • 2. Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A. Epidural versus non-epidural or no analgesia for pain management in labour. Cochrane Database Syst Rev. 2018;5(5):CD000331. doi: 10.1002/14651858.CD000331.
  • 3. Arendt K, Segal S. Why epidurals do not always work. Rev Obstet Gynecol. 2008 Spring;1(2):49-55. PMID: 18769661; PMCID: PMC2505163.
  • 4. Bautista L, George RB. Epidural analgesia in labour. CMAJ. 2020;192(19):E509. doi: 10.1503/cmaj.191372.
  • 5. George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg. 2013;116(1):133-144. doi: 10.1213/ANE.0b013e3182713b26.
  • 6. Nanji JA, Carvalho B. Pain management during labor and vaginal birth. Best Pract Res Clin Obstet Gynaecol. 2020;67:100- 112. doi: 10.1016/j.bpobgyn.2020.03.002.
  • 7. Zimmer EZ, Jakobi P, Itskovitz-Eldor J, et al. Adverse effects of epidural analgesia in labor. Eur J Obstet Gynecol Reprod Biol. 2000;89(2):153-157. doi: 10.1016/s0301-2115(99)00191-8.
  • 8. Simmons SW, Taghizadeh N, Dennis AT, Hughes D, Cyna AM. Combined spinal-epidural versus epidural analgesia in labour. Cochrane Database Syst Rev. 2012;10(10):CD003401. doi: 10.1002/14651858.CD003401.pub3.
  • 9. Hattler J, Klimek M, Rossaint R, Heesen M. The effect of combined spinal–epidural versus epidural analgesia in laboring women on nonreassuring fetal heart rate tracings: systematic review and meta-analysis. Anesth Analg. 2016;123(4): 955- 964.
  • 10. Halliday L, Nelson SM, Kearns RJ. Epidural analgesia in labor: A narrative review. Int J Gynaecol Obstet. 2022;159(2):356- 364. doi: 10.1002/ijgo.14175.
  • 11. Callahan EC, Lee W, Aleshi P, George RB. Modern labor epidural analgesia: implications for labor outcomes and maternal-fetal health. Am J Obstet Gynecol. 2023 May;228(5S):S1260-S1269. doi: 10.1016/j.ajog.2022.06.017. Epub 2023 Mar 20. PMID: 37164496.
  • 12. Olszynska A, Di Martino Z, Pawlowska A, et al. Epidural analgesia: effect on labor duration and delivery mode - a single- center cohort study. Ginekol Pol. 2023 Jun 7. doi: 10.5603/ GP.a2023.0048. Epub ahead of print. PMID: 37284824.
  • 13. Luo D, Yuan Y, Guo L, Chen Z. A comparative study of epidural labor analgesia and natural delivery without analgesia. Am J Transl Res. 2021;13(6):7015-7021.
  • 14. Genc M, Sahin N, Maral J, Celik E, Kar AA, Usar P, et al. Does bupivacaine and fentanyl combination for epidural analgesia shorten the duration of labour? J Obstet Gynaecol. 2015;35(7):672-675. doi: 10.3109/01443615.2014.991299.
  • 15. Liu X, Zhang H, Zhang H, Guo M, Gao Y, Du C. Intermittent epidural bolus versus continuous epidural infusions for labor analgesia: A meta-analysis of randomized controlled trials. PLoS One. 2020 ;15(6):e0234353. doi: 10.1371/journal. pone.0234353.
  • 16. Sng BL, Sia ATH, Lim Y, Woo D, Ocampo C. Comparison of computer-integrated patient-controlled epidural analgesia and patient-controlled epidural analgesia with a basal infusion for labour and delivery. Anaesth Intensive Care. 2009 Jan;37(1):46- 53. doi: 10.1177/0310057X0903700119.
  • 17. Roofthooft E, Barbé A, Schildermans J, et al. Programmed intermittent epidural bolus vs. patient-controlled epidural analgesia for maintenance of labour analgesia: a two-centre, double- blind, randomised study†. Anaesthesia. 2020;75(12):1635- 1642. doi: 10.1111/anae.15149.
  • 18. Agrawal D, Makhija B, Arora M, Haritwal A, Gurha P. The effect of epidural analgesia on labour, mode of delivery and neonatal outcome in nullipara of India, 2011-2014. J Clin Diagn Res. 2014;8(10):OC03-6. doi: 10.7860/JCDR/2014/9974.4930.
  • 19. Wassen MM, Smits LJ, Scheepers HC. Routine labour epidural analgesia versus labour analgesia on request: a randomised non-inferiority trial. BJOG. 2015;122(3):344-350. doi: 10.1111/1471-0528.12854.
  • 20. Wang K, Cao L, Deng Q, et al. The effects of epidural/spinal opioids in labour analgesia on neonatal outcomes: A meta- analysis of randomized controlled trials. Can J Anaesth. 2014;61(8):695-709. doi: 10.1007/s12630-014-0185-y.
  • 21. George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: A systematic review and meta-analysis. Anesth Analg. 2013;116(1):133-144. doi: 10.1213/ANE.0b013e3182713b26.
  • 22. Šakić L, Vidaković Z, Šakić K, Radoš I, Včev A. Satisfaction Of Parturients With Epidural Analgesia During Delivery: Analysis Of Questionnaire At A Single Hospital Center. Acta Clin Croat. 2022 ;61(Suppl 2):9-14. doi: 10.20471/acc.2022.61.s2.01.

Evaluation of Epidural Analgesia for Vaginal Delivery: A Retrospective Analysis of a State Hospital

Year 2024, Volume: 8 Issue: 3, 307 - 313, 30.12.2024

Abstract

Aim: Epidural analgesia is the most commonly preferred analgesia method for labour pain management. Our purpose is to examine the
effects of epidural analgesia on the mother, fetus, and the labour process in this study.
Material and Methods: The files of pregnant women undergoing epidural analgesia for labour between January and December 2017
were examined retrospectively. Demographic data, hemodynamic parameters, duration of labour stages, rates of conversion to caesarean
section, visual analogue scale (VAS) scores before and after epidural, APGAR score, maternal and fetal side effects, and satisfaction of
pregnant women were evaluated.
Results: It was seen that VAS scores were 2-3 with our painless labor analgesia protocol, caesarean rate was 2% among 153 labourers, the
hypotension rate was 3.9% as a material side effect, the pregnancy satisfaction rate and the rate of requesting another epidural were 85.6%,
and the 1st- and 5th-minute APGAR scores were 9-10 without any adverse effects.
Conclusion: Epidural analgesia is a method that should be applied with a multi-disciplinary approach by experienced practitioners and
obstetricians. This method dramatically reduces both the pain and stress of the mother and increases labour comfort, and we recommend it
to all eligible pregnant women for a painless vaginal delivery.

References

  • 1. Wong CA. Epidural and spinal analgesia/anesthesia for labor and vaginal delivery. In: Chestnut’s Obstetric Anesthesia: Principles and Practice. 5th ed. Philadelphia, PA: Elsevier/Saunders; 2014:457-517
  • 2. Anim-Somuah M, Smyth RM, Cyna AM, Cuthbert A. Epidural versus non-epidural or no analgesia for pain management in labour. Cochrane Database Syst Rev. 2018;5(5):CD000331. doi: 10.1002/14651858.CD000331.
  • 3. Arendt K, Segal S. Why epidurals do not always work. Rev Obstet Gynecol. 2008 Spring;1(2):49-55. PMID: 18769661; PMCID: PMC2505163.
  • 4. Bautista L, George RB. Epidural analgesia in labour. CMAJ. 2020;192(19):E509. doi: 10.1503/cmaj.191372.
  • 5. George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: a systematic review and meta-analysis. Anesth Analg. 2013;116(1):133-144. doi: 10.1213/ANE.0b013e3182713b26.
  • 6. Nanji JA, Carvalho B. Pain management during labor and vaginal birth. Best Pract Res Clin Obstet Gynaecol. 2020;67:100- 112. doi: 10.1016/j.bpobgyn.2020.03.002.
  • 7. Zimmer EZ, Jakobi P, Itskovitz-Eldor J, et al. Adverse effects of epidural analgesia in labor. Eur J Obstet Gynecol Reprod Biol. 2000;89(2):153-157. doi: 10.1016/s0301-2115(99)00191-8.
  • 8. Simmons SW, Taghizadeh N, Dennis AT, Hughes D, Cyna AM. Combined spinal-epidural versus epidural analgesia in labour. Cochrane Database Syst Rev. 2012;10(10):CD003401. doi: 10.1002/14651858.CD003401.pub3.
  • 9. Hattler J, Klimek M, Rossaint R, Heesen M. The effect of combined spinal–epidural versus epidural analgesia in laboring women on nonreassuring fetal heart rate tracings: systematic review and meta-analysis. Anesth Analg. 2016;123(4): 955- 964.
  • 10. Halliday L, Nelson SM, Kearns RJ. Epidural analgesia in labor: A narrative review. Int J Gynaecol Obstet. 2022;159(2):356- 364. doi: 10.1002/ijgo.14175.
  • 11. Callahan EC, Lee W, Aleshi P, George RB. Modern labor epidural analgesia: implications for labor outcomes and maternal-fetal health. Am J Obstet Gynecol. 2023 May;228(5S):S1260-S1269. doi: 10.1016/j.ajog.2022.06.017. Epub 2023 Mar 20. PMID: 37164496.
  • 12. Olszynska A, Di Martino Z, Pawlowska A, et al. Epidural analgesia: effect on labor duration and delivery mode - a single- center cohort study. Ginekol Pol. 2023 Jun 7. doi: 10.5603/ GP.a2023.0048. Epub ahead of print. PMID: 37284824.
  • 13. Luo D, Yuan Y, Guo L, Chen Z. A comparative study of epidural labor analgesia and natural delivery without analgesia. Am J Transl Res. 2021;13(6):7015-7021.
  • 14. Genc M, Sahin N, Maral J, Celik E, Kar AA, Usar P, et al. Does bupivacaine and fentanyl combination for epidural analgesia shorten the duration of labour? J Obstet Gynaecol. 2015;35(7):672-675. doi: 10.3109/01443615.2014.991299.
  • 15. Liu X, Zhang H, Zhang H, Guo M, Gao Y, Du C. Intermittent epidural bolus versus continuous epidural infusions for labor analgesia: A meta-analysis of randomized controlled trials. PLoS One. 2020 ;15(6):e0234353. doi: 10.1371/journal. pone.0234353.
  • 16. Sng BL, Sia ATH, Lim Y, Woo D, Ocampo C. Comparison of computer-integrated patient-controlled epidural analgesia and patient-controlled epidural analgesia with a basal infusion for labour and delivery. Anaesth Intensive Care. 2009 Jan;37(1):46- 53. doi: 10.1177/0310057X0903700119.
  • 17. Roofthooft E, Barbé A, Schildermans J, et al. Programmed intermittent epidural bolus vs. patient-controlled epidural analgesia for maintenance of labour analgesia: a two-centre, double- blind, randomised study†. Anaesthesia. 2020;75(12):1635- 1642. doi: 10.1111/anae.15149.
  • 18. Agrawal D, Makhija B, Arora M, Haritwal A, Gurha P. The effect of epidural analgesia on labour, mode of delivery and neonatal outcome in nullipara of India, 2011-2014. J Clin Diagn Res. 2014;8(10):OC03-6. doi: 10.7860/JCDR/2014/9974.4930.
  • 19. Wassen MM, Smits LJ, Scheepers HC. Routine labour epidural analgesia versus labour analgesia on request: a randomised non-inferiority trial. BJOG. 2015;122(3):344-350. doi: 10.1111/1471-0528.12854.
  • 20. Wang K, Cao L, Deng Q, et al. The effects of epidural/spinal opioids in labour analgesia on neonatal outcomes: A meta- analysis of randomized controlled trials. Can J Anaesth. 2014;61(8):695-709. doi: 10.1007/s12630-014-0185-y.
  • 21. George RB, Allen TK, Habib AS. Intermittent epidural bolus compared with continuous epidural infusions for labor analgesia: A systematic review and meta-analysis. Anesth Analg. 2013;116(1):133-144. doi: 10.1213/ANE.0b013e3182713b26.
  • 22. Šakić L, Vidaković Z, Šakić K, Radoš I, Včev A. Satisfaction Of Parturients With Epidural Analgesia During Delivery: Analysis Of Questionnaire At A Single Hospital Center. Acta Clin Croat. 2022 ;61(Suppl 2):9-14. doi: 10.20471/acc.2022.61.s2.01.
There are 22 citations in total.

Details

Primary Language English
Subjects Anaesthesiology
Journal Section Research Article
Authors

Keziban Bollucuoğlu 0000-0002-7111-8685

Bengü Gülhan Köksal 0000-0002-1324-6144

Publication Date December 30, 2024
Submission Date October 17, 2024
Acceptance Date December 18, 2024
Published in Issue Year 2024 Volume: 8 Issue: 3

Cite

Vancouver Bollucuoğlu K, Köksal BG. Evaluation of Epidural Analgesia for Vaginal Delivery: A Retrospective Analysis of a State Hospital. Med J West Black Sea. 2024;8(3):307-13.

Medical Journal of Western Black Sea is a scientific publication of Zonguldak Bulent Ecevit University Faculty of Medicine.

This is a refereed journal, which aims at achieving free knowledge to the national and international organizations and individuals related to medical sciences in publishedand electronic forms.

This journal is published three annually in April, August and December.
The publication language of the journal is Turkish and English.