Immune Thrombocytopenic Purpura Secondary to Varicella Zoster Infection: A Case Report

Abstract

Varicella zoster  infection  is usually considered to be benign despite of serious complications.  Immune Thrombocytopenic Purpura (ITP) is usually a self-limiting disorder in children. ITP is an autoimmune disorder in which antibody-coated or immune complex–coated platelets are destroyed prematurely by the reticuloendothelial system, resulting in peripheral thrombocytopenia.  In primary ITP the thrombocytopenia is isolated, whereas in secondary ITP the condition is associated with other disorders (e.g. Systemic Lupus Erythematous, HIV, VZV). We describe a case of  immune Thrombocytopenic Purpura secondary to varicella infection in a previously healthy 7-y-old boy. He was treated successfully with intravenous immunoglobulin (IVIG).

Keywords

• Varicella Zoster Infection,Immune Thrombocytopenic Purpura,Child

Varicella Zoster Enfeksiyonunu Takiben Gelişen İmmun Trombositopenik Purpura

Abstract

Varicella Zoster Virüs (VZV) enfeksiyonu genellikle bening olmasına rağmen ciddi komplikasyonlara neden olabilen enfeksiyoz bir hastalıktır. İmmün Trombositopenik Purpura (ITP) genellikle çocuklarda kendi kendini sınırlayan bir hastalıktır. ITP, antikor kaplı veya immün kompleksle kaplanmış trombositlerin retiküloendotelyal sistem tarafından prematür olarak yok edildiği ve periferik trombositopeni ile sonuçlanan otoimmün bir bozukluktur. Primer ITP'de trombositopeni ile ilişkili iken sekonder ITP'de durum diğer bozukluklarla (örn. Sistemik Lupus Eritematosuz, HIV enfeksiyonu, VZV) ilişkilidir. Bu olgu sunumunda; önceden sağlıklı olan, VZV enfeksiyonuna bağlı ITP gelişen ve İntravenöz immünoglobulin ile başarılı bir şekilde tedavi edilen 7 yaşında bir olgu anlatılacaktır.

Keywords

• Varicella Zoster,İmmün Trombositopenik Purpura,intravenöz immünoglobulin

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