DIURNAL ENURESIS SECONDARY TO ARIPIPRAZOLE

Abstract

Aripiprazole is a second-generation antipsychotic drug that is partial agonist of dopamine D2 receptor. It is used in the treatment of some psychiatric disorders such as schizophrenia, bipolar disorder. It has rarely been reported that aripiprazole has side effects of urinary retention and enuresis in children. In this case presentation diurnal enuresis secondary to aripiprazole treatment will be discussed.

Keywords

• Aripiprazole,dopamine,diurnal enuresis

Aripiprazol Sonrası Gelişen Diurnal Enürezis Hüseyin

Abstract

Aripiprazol parsiyel D2 reseptör agonisti olan ikinci kuşak bir antipsikotik ilaçtır. Bipolar bozukluk ve şizofreni gibi bazı psikiyatrik rahatsızlıkların tedavisinde kullanılmaktadır. Çocuklarda aripiprazolün üriner retansiyon ve enürezis yan etkileri nadiren bildirilmiştir. Bu olgu sunumunda, aripiprazol tedavisine sekonder gelişen bir diürnal enuüezis tartışılacaktır.

Keywords

• Aripiprazol,dopamin,diurnal enürezis

References

1. Bloom DA, Seeley WW, Ritchey ML, McGuire EJ. Toilet habits and continence in children: an opportunity sampling in search of normal parameters. J Urol. 1993 May;149(5):1087–90.
2. Lee M-J, Kim C-E. Use of aripiprazole in clozapine induced enuresis: report of two cases. J Korean Med Sci. 2010 Feb;25(2):333–5.
3. Bozkurt H, Abali O. Aripiprazole-Induced Enuresis in a Child with Autistic Disorder. Otizm Tanılı Bir Cocukta Aripiprazole Baglı Enurezis. 2011 Jun;48(2):164–6.
4. Yalcin O. Micturition difficulty and urinary retention associated with aripiprazole and citalopram treatment in a male adolescent with Asperger syndrome. J Child Adolesc Psychopharmacol. 2014 Dec;24(10):598– 9.
5. Karakurt MN, Suren S. Desmopressin Use in the Treatment of Aripiprazole-Induced Nocturnal Enuresis in a Child Diagnosed with Autıstıc Disorder. J Child Adolesc Psychopharmacol. 2015 Aug;25(6):518–9.
6. Kılınc S, Herguner A, Herguner S. Cessation of Nocturnal Enuresis with Aripiprazole. J Child Adolesc Psychopharmacol. 2017 Mar;27(2):213–4.
7. Candura SM, Messori E, Franceschetti GP, D’Agostino G, Vicini D, Tagliani M, et al. Neural 5-HT4 receptors in the human isolated detrusor muscle: effects of indole, benzimidazolone and substituted benzamide agonists and antagonists. Br J Pharmacol. 1996 Aug;118(8):1965–70.
8. Ozdemir PG, Aydın A, Gulec M, Cim EFA. Switching to Fluoxetine in a Case of Sertraline-Induced Urinary Incontinence: A Case Report -. Duşunen Adam J Psychiatry Neurol Sci. 2013;26(1):117–8.

9. Herguner S, Kilincaslan A, Gorker I, Tuzun U. Serotonin-selective reuptake inhibitorinduced enuresis in three pediatric cases. J Child Adolesc Psychopharmacol. 2007 Jun;17(3):367–9.
10. Testa R, Guarneri L, Poggesi E, Angelico P, Velasco C, Ibba M, et al. Effect of several 5-hydroxytryptamine(1A) receptor ligands on the micturition reflex in rats: comparison with WAY 100635. J Pharmacol Exp Ther. 1999 Sep;290(3):1258–69.