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A CASE REPORT: FACIAL PARALYSIS AS THE PRESENTING MANIFESTATION OF ACUTE LYMPHOBLASTIC LEUKEMIA

Year 2010, Volume: 1 Issue: 3, - , 03.03.2015

Abstract

Although facial paralysis is encountered as a complication of leukemias in children, it is very seldom to be seen as only and diagnostic symptom. We report herein, a 16-month- old female, who was previously diagnosed as an idiopathic facial palsy and treated with steroid, is found out to be suffering from acute lymphoblastic leukemia that was a real etiological factor of the facial palsy afterwards. This case accentuates the importance of primary investigation and also the consideration of hematologic malignancies in children with facial
paralysis.

References

  • Smith V, Traquina DN. Pediatric bilateral facial paralysis. Laryngoscope 1998; 108: 519-23.
  • May M, Fria TJ, Blumenthal F, Curtin H. Facial paralysis in children: Differential diagnosis. Otolaryngol Head Neck Surg 1981; 89: 841-8.
  • Ingram LC, Fairclough DL, Furman WL, et al. Cranial nerve palsy in childhood acute lymphoblastic leukemia and non-Hodgkin’s lymphoma. Cancer 1991; 67: 2262-8.
  • Zappia JJ, Bunge FA, Koopman CF Jr., McClathey KD. Facial nerve paresis as the presenting symptom of leukemia. Int J Pediatr Otorhinolaringol 1990; 19: 259-64.
  • Levy R, Har-El G, Segal K, Sidi J, Acute myelogenous leukemia presenting as facial paralysis in children. Int J Pediatr Otorhinolaryngol 1986; 49-53.
  • Grundfast KM, Guarisco JL, Thomsen JR, Koch B. Diverse etiologies of facial paralysis in children. Int J Pediatr Otorhinolaryngol 1990; 19: 223-39.
  • Manning JJ, Adour KK. Facial paralysis in children. Pediatrics 1972; 49: 102-9.
  • Todd NW, Bowman CA. Acute myelogenous leukemia presenting as atypical mastoiditis with facial paralysis. Int J Pediatr Otorhinolaryngol 1984; 7: 173-7.
  • Wright JL. Acute leukemia presenting as acute mastoidits. J Lary6ngol Otol 1971; 85: 1087-91.
  • Eser B, Cetin M, Kontas O, et al. Facial nerve paralysis and paraplegia as presenting symptoms of acute myeloid leukemia. Jpn J Clin Oncol 2001; 31: 86-8.
  • Hauser WA, Karnes WE, Aniis J, Kurland LT. Incıdense and prognosis of Bell’s palsy in the population of Rochester, Minnesota. Mayo Clin Proc 1971; 46: 258-64.
  • Tubergen DG, Bleyer A. The leukemias. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson textbook of pediatrics, 17th ed. Philadelphia: WB Saunders; 2003: 1694-8.
  • Lilleyman JS, Antoniou AG, Sugden PJ. Facial nevre palsy in acute leukaemia. Scand J Haematol ; 22: 87-90. Krishnamurthy S, Weinstock AL, Smith SH, Duffner PK. Facial palsy, an unusual presenting feature of childhood leukemia. Pediatr Neurol 2002; 27: 68-70
  • Cartwright RA, Boddy J, Barnard D, et al. Association between Bell’s palsy and lymphoid malignancies. Leuk Res 1985; 9: 31-3.

OLGU SUNUMU: AKUT LENFOBLASTİK LÖSEMİNİN BAŞVURU BULGUSU OLARAK FASİAL PARALİZİ

Year 2010, Volume: 1 Issue: 3, - , 03.03.2015

Abstract

Fasial paralizi çocuklardaki lösemilerinin bir komplikasyonu olarak karşılaşılmasına rağmen lösemilerde ilk ve tanı koydurucu semptom olarak görülmesi çok nadirdir. Burada daha önce idiyopatik fasial paralizi tanısı ile steroid tedavisi verilen fakat sonradan etiyolojik faktörün akut lenfoblastik lösemi olduğu anlaşılan 16 aylık bir kız çocuk rapor edildi. Bu olgu fasial paralizili çocuklarda hematolojik malignensilerin de düşünülmesi ve primer araştırılmasının önemini vurgulamaktadır.Fasial paralizi çoğunlukla prognozu iyi olan ve “Bell’s palsi” olarak da bilinen selim bir durumdur. Lyme hastalığı, akut otitis media ve lösemi gibi pek çok etiyolojik ajan bildirilmesine rağmen vakaların çoğu hala idiyopatiktir (1). Lösemili çocuklarda santral sinir sistemi tutulumunun bir göstergesi olabilir.

References

  • Smith V, Traquina DN. Pediatric bilateral facial paralysis. Laryngoscope 1998; 108: 519-23.
  • May M, Fria TJ, Blumenthal F, Curtin H. Facial paralysis in children: Differential diagnosis. Otolaryngol Head Neck Surg 1981; 89: 841-8.
  • Ingram LC, Fairclough DL, Furman WL, et al. Cranial nerve palsy in childhood acute lymphoblastic leukemia and non-Hodgkin’s lymphoma. Cancer 1991; 67: 2262-8.
  • Zappia JJ, Bunge FA, Koopman CF Jr., McClathey KD. Facial nerve paresis as the presenting symptom of leukemia. Int J Pediatr Otorhinolaringol 1990; 19: 259-64.
  • Levy R, Har-El G, Segal K, Sidi J, Acute myelogenous leukemia presenting as facial paralysis in children. Int J Pediatr Otorhinolaryngol 1986; 49-53.
  • Grundfast KM, Guarisco JL, Thomsen JR, Koch B. Diverse etiologies of facial paralysis in children. Int J Pediatr Otorhinolaryngol 1990; 19: 223-39.
  • Manning JJ, Adour KK. Facial paralysis in children. Pediatrics 1972; 49: 102-9.
  • Todd NW, Bowman CA. Acute myelogenous leukemia presenting as atypical mastoiditis with facial paralysis. Int J Pediatr Otorhinolaryngol 1984; 7: 173-7.
  • Wright JL. Acute leukemia presenting as acute mastoidits. J Lary6ngol Otol 1971; 85: 1087-91.
  • Eser B, Cetin M, Kontas O, et al. Facial nerve paralysis and paraplegia as presenting symptoms of acute myeloid leukemia. Jpn J Clin Oncol 2001; 31: 86-8.
  • Hauser WA, Karnes WE, Aniis J, Kurland LT. Incıdense and prognosis of Bell’s palsy in the population of Rochester, Minnesota. Mayo Clin Proc 1971; 46: 258-64.
  • Tubergen DG, Bleyer A. The leukemias. In: Behrman RE, Kliegman RM, Jenson HB, eds. Nelson textbook of pediatrics, 17th ed. Philadelphia: WB Saunders; 2003: 1694-8.
  • Lilleyman JS, Antoniou AG, Sugden PJ. Facial nevre palsy in acute leukaemia. Scand J Haematol ; 22: 87-90. Krishnamurthy S, Weinstock AL, Smith SH, Duffner PK. Facial palsy, an unusual presenting feature of childhood leukemia. Pediatr Neurol 2002; 27: 68-70
  • Cartwright RA, Boddy J, Barnard D, et al. Association between Bell’s palsy and lymphoid malignancies. Leuk Res 1985; 9: 31-3.
There are 14 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Yasemin Torun This is me

Fatma Mutlu This is me

Berna Saygın This is me

Fatmagül Başarslan This is me

Publication Date March 3, 2015
Submission Date February 28, 2015
Published in Issue Year 2010 Volume: 1 Issue: 3

Cite

Vancouver Torun Y, Mutlu F, Saygın B, Başarslan F. A CASE REPORT: FACIAL PARALYSIS AS THE PRESENTING MANIFESTATION OF ACUTE LYMPHOBLASTIC LEUKEMIA. mkutfd. 2015;1(3).