Abstract
Introduction: Angiomatous meningioma is a rare variant which accounts for 2.1% of all
meningiomas. It has features of a typical benign meningioma with many small or large
vascular channels which may predominate over its meningothelial elements.We present here
our case which is a rare variant of meningiomas that has located on the anterior
cerebellopontin cistern.
Case History: A 56 year old woman was referred to the outpatient clinic of Mustafa Kemal
University (MKU) Neurosurgery Department due to headache and numbness. On computed
tomography examination a mass with 33X26 mm seize and intense contrast enhancement has
been obtained. The patient was sent to surgery with meningioma prediagnosis. The diagnosis
has been confirmed as meningioma, angiomatous variant by microscobic examination in
MKU Pathology Laboratory.
Conclusion: Angiomatous meningioma is a rare variant of meningioma with middle-aged
women predominance. Histopathologic features and immunohisto chemistry studies
distinguish these lesions from vascular malformations and hemangioblastoma.
Keywords
References
- Rao S, Rajkumar A, Kuruvilla S. Angiomatous meningioma: A diagnostic dilemma. Indian Journal of Pathology and Microbiology. 2008;51.53-5
- Kleihues P, Cavenee WK. World Health Organization classification of tumors. Pathology and genetics of tumors of the nervous system. Lyon: IARC Press; 2000:175-93.
- Deb P, Sahni H, Bhatoe HS. Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. Journal of Cancer Research and Therapeotics. 2010;6.560-3.
- Martin H, Kay WN, Werner P. Angiomatous meningioma - A clinicopathologic study of 38 cases. American Journal of Surgical Pathology. 2004;28.390-34.
- Peter CB, James SN, Orest BB. Diagnostic synergy in radiology and surgical neuropathology. Archieves of Pathology and Laboratory Medicine. 1998;122.620-32.
- Tamiya T, Ono Y, Matsumoto K, Ohmoto T. Peritumoral brain edema in intracranial meningiomas: effects of radiological and histological factors. Neurosurgery. 2001;49.1046-51
- Stacey E. Mills Sternberg's Diagnostic Surgical Pathology, 4th ed. Lippincott William and Wilkins; 2004:460-81.
Abstract
GİRİŞ: Anjiomatöz meningiomalar, tüm meningiomaların %2.1’lik kısmını oluşturan nadir
rastlanılan bir varyantıdır. Benign meningiomaların tipik özelliklerine sahip olmakla beraber
meningial elemanlardan daha baskın olabilen küçük veya büyük vasküler kanallardan
oluşurlar. Biz de sol serebellopontin sistern anterioruna yerleşim gösteren az rastlanılan bir
meningiom varyantı olan olgumuzu sunmak istedik.
OLGU SUNUMU: 56 yaşında bayan hasta 3 aydır devam eden sol yüz yan tarafına yayılan
baş ağrısı ve uyuşma şikayetiyle Mustafa Kemal Üniversitesi (MKÜ) Tıp Fakültesi Hastanesi
Nöroşirürji Polikliniğine başvurmuştur. Hastanın kontrastlı bilgisayar tomografi
görüntülemesinde sol serebellopontin sistern anterioruna yerleşim göstermiş 33x26 mm
boyutlarında yoğun kontrast tutan kitle tespit edilmiştir Hasta meningiom ön tanısıyla opere
edildikten sonra materyalin MKÜ Tıp Fakültesi Patoloji Bölümündeki mikroskobik
incelemesinde meningioma, anjiomatöz variant olarak tanı kesinleştirilmiştir.
TARTIŞMA: Anjiomatöz meningiomalar meningiomaların nadir rastlanılan bir subgrubu
olup, orta yaşlardaki bayanlarda sıklıkla gözlenirler. Tipik meningiomalara özgü
histopatolojik görünümleri ve immunohistokimyasal çalışmalar anjiomatöz meningiomu
vasküler malformasyonlar ve hemanjioblastomalardan ayırt ettirir.
Keywords
References
- Rao S, Rajkumar A, Kuruvilla S. Angiomatous meningioma: A diagnostic dilemma. Indian Journal of Pathology and Microbiology. 2008;51.53-5
- Kleihues P, Cavenee WK. World Health Organization classification of tumors. Pathology and genetics of tumors of the nervous system. Lyon: IARC Press; 2000:175-93.
- Deb P, Sahni H, Bhatoe HS. Cystic angiomatous meningioma in the cerebellopontine angle mimicking hemangioblastoma. Journal of Cancer Research and Therapeotics. 2010;6.560-3.
- Martin H, Kay WN, Werner P. Angiomatous meningioma - A clinicopathologic study of 38 cases. American Journal of Surgical Pathology. 2004;28.390-34.
- Peter CB, James SN, Orest BB. Diagnostic synergy in radiology and surgical neuropathology. Archieves of Pathology and Laboratory Medicine. 1998;122.620-32.
- Tamiya T, Ono Y, Matsumoto K, Ohmoto T. Peritumoral brain edema in intracranial meningiomas: effects of radiological and histological factors. Neurosurgery. 2001;49.1046-51
- Stacey E. Mills Sternberg's Diagnostic Surgical Pathology, 4th ed. Lippincott William and Wilkins; 2004:460-81.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 3, 2015 |
| Submission Date | February 28, 2015 |
| Published in Issue | Year 2011 Volume: 2 Issue: 8 |
