Immune Thrombocytopenic Purpura Secondary to Varicella Zoster Infection: A Case Report

Year 2017, Volume: 8 Issue: 32, 29 - 33, 31.12.2017

Yasin Yıldız , Serdar Özkasap Tuğba Calaboğlu Elif Karadeniz Semiha Çakmak , Zeynep Hocoğlu

https://doi.org/10.17944/mkutfd.304238

Abstract

Varicella zoster 
infection  is usually considered
to be benign despite of serious complications. 
Immune Thrombocytopenic Purpura (ITP) is usually
a self-limiting disorder in children. ITP is an autoimmune disorder in which
antibody-coated or immune complex–coated platelets are destroyed prematurely by
the reticuloendothelial system, resulting in peripheral thrombocytopenia.  In primary ITP the thrombocytopenia is
isolated, whereas in secondary ITP the condition is associated with other
disorders (e.g. Systemic Lupus Erythematous, HIV, VZV). We describe a case
of  immune Thrombocytopenic
Purpura secondary to varicella infection in a previously
healthy 7-y-old boy. He was treated successfully with intravenous immunoglobulin (IVIG).

Keywords

Varicella Zoster Infection, Immune Thrombocytopenic Purpura, Child

Varicella Zoster Enfeksiyonunu Takiben Gelişen İmmun Trombositopenik Purpura

Abstract

Varicella Zoster Virüs (VZV) enfeksiyonu
genellikle bening olmasına rağmen ciddi
komplikasyonlara neden olabilen
enfeksiyoz bir hastalıktır. İmmün Trombositopenik
Purpura (ITP) genellikle
çocuklarda kendi kendini sınırlayan bir hastalıktır. ITP, antikor kaplı veya
immün kompleksle kaplanmış trombositlerin retiküloendotelyal sistem tarafından
prematür olarak yok edildiği ve periferik trombositopeni ile sonuçlanan
otoimmün bir bozukluktur. Primer ITP'de trombositopeni ile ilişkili iken
sekonder ITP'de durum diğer bozukluklarla (örn. Sistemik Lupus Eritematosuz,
HIV enfeksiyonu, VZV) ilişkilidir. Bu olgu sunumunda; önceden sağlıklı olan, VZV
enfeksiyonuna bağlı ITP gelişen ve İntravenöz immünoglobulin ile başarılı bir
şekilde tedavi edilen 7 yaşında bir olgu anlatılacaktır.

Keywords

Varicella Zoster, İmmün Trombositopenik Purpura, intravenöz immünoglobulin

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