Year 2018, Volume 9 , Issue 35, Pages 155 - 160 2018-12-31

Erişkin Başlangıçlı Langerhans Hücreli Histiyositoz
Adult Onset Langerhans Cell Histiocytosis

Zeynep BAYRAMOĞLU [1] , Muhammet Zeki GÜLTEKİN [2] , Yaşar ÜNLÜ [3]


Langerhans hücreli histiyositoz (LHH), Langerhans hücrelerinin klonal ve neoplastik proliferasyonu ile karakterize nadir bir hastalıktır. En sık çocuklarda tanı almakla beraber, her yaşta görülebilir. Klinik bulgular, tutulan organ sistemine göre değişmektedir. LHH'nin kesin tanısı histopatolojik olarak konulmaktadır. LHH’un tedavisi, hastalığın bulunduğu organ sistemine ve lezyonların yaygınlığına göre planlanmaktadır. Biz burada erişkin yaş başlangıçlı, femur tutulumu olan 33 yaşında erkek hastanın klinik, radyolojik ve histapatolojik bulguları sunularak güncel literatür eşliğinde tartışmayı amaçladık.

Langerhans cell histiocytosis (LCH) is a rare disease characterized by clonal and neoplastic proliferation of Langerhans cells. It is most commonly seen in children but can be seen at any age. Clinical findings depend on the organ system involved. The diagnosis of LCH is made histopathologically. The treatment is planned according to the organ system of the disease, the prevalence of the lesions and the presence of specific organ dysfunction. We aimed to discuss the clinical, radiological and histapatological findings of a 33-year-old man with femoral involvement at adulthood and discuss the current literature.

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Primary Language tr
Subjects Health Care Sciences and Services
Journal Section Olgu Sunumu
Authors

Orcid: 0000-0001-7075-8819
Author: Zeynep BAYRAMOĞLU
Institution: SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KONYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ
Country: Turkey


Orcid: 0000-0003-2160-8237
Author: Muhammet Zeki GÜLTEKİN
Institution: UNIVERSITY OF HEALTH SCIENCES, HEALTH RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES
Country: Turkey


Orcid: 0000-0002-3951-8881
Author: Yaşar ÜNLÜ
Institution: SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, KONYA SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ
Country: Turkey


Dates

Application Date : November 14, 2018
Acceptance Date : December 25, 2018
Publication Date : December 31, 2018

Vancouver Bayramoğlu Z , Gülteki̇n M , Ünlü Y . Erişkin Başlangıçlı Langerhans Hücreli Histiyositoz. Mustafa Kemal Üniversitesi Tıp Dergisi. 2018; 155-160.