Year 2020, Volume 11 , Issue 40, Pages 48 - 54 2020-08-30

The Effects of Aerobic Exercise on Thyroid Hormone Levels in Obese Boys
Aerobik Egzersizin Obez Erkek Çocuklarda Tiroid Hormon Düzeylerine Etkisi

Nuray Satılmış [1] , Yahya Polat [2] , Behzat Çimen [3] , Leyla Cimen [4] , İhsan Çetin [5]


Aim: Although beneficial effects of physical exercises on adulthood obesity are well known, it is unclear how physical exercises affect thyroid hormone related body composition, basal metabolic rate and thermogenesis in obese children. Our objective is to examine the effects of physical exercise program on 3-5-3’triiodothyronine (T3) and 3-5-3’-5’tetraiodothyronine (T4) in obese boys.
Materials and Method: Our study consisted of 10 obese boys (aged from 13 to 15) and a control group of 10 healthy boys age and gender matched. Before exercise program, 10 ml blood samples were taken from the obese and control group boys; and 10 ml blood samples were taken from the obese boys after program exercise 3 days/week for 12 weeks. The lipid profiles, creatine kinase (CK), creatine kinase-MB, T3 and T4 levels in blood samples were measured for both groups.
Results: In present study, it was found that control group and obese boys after aerobic exercise had significantly higher T3 and T4 levels (1.63±0.17; 9.80±0.93 and 1.70±0.10; 10.1±0.54, respectively) and significantly lower CK levels (142.7±4.11 and 151.8±3.70, respectively) than those of obese boys before aerobic exercise (1.19±0.81; 7.37±0.47 and 165.3±2.49, respectively). Furthermore, it was found that aerobic exercise significantly decreased triglyceride and cholesterol levels in obese boys (104.0±3.77 and 193.7±2.90, respectively).
Conclusion: When these findings are taken into account, it may be suggested that aerobic exercises can help with the improvement of decreased thyroid hormone levels which may be cause a weight increase together with a decrease in basal metabolic rate and thermogenesis in obese boys. 

Amaç: Fiziksel egzersizlerin obezite üzerindeki yararlı etkileri iyi bilinse de, obez çocuklarda fiziksel egzersizlerin tiroid hormonuna bağlı vücut kompozisyonunu, bazal metabolik hızı ve termojenezi nasıl etkilediği açık değildir. Amacımız, obez erkek çocuklarda egzersiz programının 3-5-3’triiyodotironin (T3) ve 3-5-3’-5’tetraiodotironin (T4) üzerindeki etkilerini incelemektir.
Gereç ve Yöntemler: Çalışmamız 10 obez erkek (13-15 yaş arası) ve kontrol grubu olarak 10 sağlıklı erkek çocuktan oluşuyordu. Egzersiz programından önce obez ve kontrol grubu erkek çocuklardan 10 ml kan örneği alındı; 12 hafta boyunca haftada 3 gün/hafta egzersizden sonra obez çocuklardan 10 ml kan örneği alındı. Her iki grubun kan örneklerinde lipit profilleri, kreatin kinaz (CK), kreatin kinaz-MB (CK-MB), T3 ve T4 düzeyleri ölçüldü.
Bulgular: Bu çalışmada, aerobik egzersizi öncesi obez çocuklarla (sırasıyla, 1.19±0.81; 7.37±0.47 and 165.3±2.49) kıyaslandığı zaman kontrol grubu ve aerobik egzersiz sonrası obez erkek çocukların anlamlı olarak daha yüksek T3 ve T4 düzeyleri (sırasıyla, 1.63±0.17; 9.80±0.93 and 1.70±0.10; 10.1±0.54) ve anlamlı derecede daha düşük CK düzeylerine (sırasıyla, 142.7±4.11 and 151.8±3.70) sahip oldukları görülmüştür. Ayrıca, aerobik egzersizin obez erkeklerde trigliserit ve kolesterol seviyelerini anlamlı derecede azalttığı bulundu (sırasıyla, 104.0±3.77 and 193.7±2.90).
Sonuç: Bu bulgular dikkate alındığında, aerobik egzersizlerin, obez erkek çocuklarda bazal metabolik hız ve termojenezde azalma ile birlikte kilo artışına neden olabilecek azalmış tiroid hormon düzeylerinin iyileştirilmesinde yardımcı olabileceği öne sürülebilir.

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Primary Language en
Subjects Health Care Sciences and Services
Journal Section Original Articles
Authors

Orcid: 0000-0002-2086-1436
Author: Nuray Satılmış
Institution: Alanya Alaaddin Keykubat University, Health Sciences Institute, Department of Physical Education and Sports
Country: Turkey


Orcid: 0000-0002-5512-5869
Author: Yahya Polat
Institution: Erciyes University, High school of Physical Education and Sports, Department of Physical Education and Sports
Country: Turkey


Orcid: 0000-0001-6904-1474
Author: Behzat Çimen
Institution: Erciyes University, Faculty of Pharmacy, Department of Biochemistry
Country: Turkey


Orcid: 0000-0002-4730-5595
Author: Leyla Cimen
Institution: Erciyes University, Faculty of Medicine, Department of Medical Biochemistry
Country: Turkey


Orcid: 0000-0002-0937-0054
Author: İhsan Çetin (Primary Author)
Institution: Hitit University, Faculty of Medicine, Department of Medical Biochemistry
Country: Turkey


Dates

Application Date : April 18, 2019
Acceptance Date : May 3, 2020
Publication Date : August 30, 2020

Vancouver Satılmış N , Polat Y , Çimen B , Cimen L , Çetin İ . The Effects of Aerobic Exercise on Thyroid Hormone Levels in Obese Boys. Mustafa Kemal Üniversitesi Tıp Dergisi. 2020; 48-54.