Sakarya Eğitim ve Araştırma Hastanesine Başvuran Hastaların HOMA-IR Değerlerinin Yaş ve Cinsiyet Faktörü Açısından Değerlendirilmesi

Year 2021, Volume: 12 Issue: 42, 1 - 4, 15.04.2021

Mehmet Özdin Hayrullah Yazar Durhasan Mundan

https://doi.org/10.17944/mkutfd.791428

Abstract

Amaç: Bu çalışmada, farklı rahatsızlıklar sebebiyle hastanemizin farklı polikliniklerine başvuran bireylerin HOMA-IR değerlerini tespit etmek amaçlanmıştır. Bu çalışma, bireylerin insülin direncini belirlemek için yapılmıştır.
Materyal Metot: Çalışmamızda, hastanemizin farklı polikliniklerine başvuran 7815 hastaya ait veriler incelenerek insülin direnci parametreleri kaydedildi. Materyal olarak 7815 hasta (1740 erkek, 6075 kadın) değerlendirildi. Bu çalışmada insülin direnci; homeostatic model değerlendirme (HOMA) metoduyla ölçüldü. Homeostatic model assessment insulin resistance (HOMA-IR) skoru ≥ 2.7 değerlere sahip olan bireylerin insülin direnci olduğu kabul edildi.
Bulgular: Hastanemizin farklı polikliniklerine müracaat eden hastaların yaş ortalaması 40.89±0.16 yıl olarak hesaplandı. Bu hastaların 4681’i (%59.90) insülin dirençli olduğu hesaplandı. İnsülin direnci olan ve olmayan grup arasında yaş ve cinsiyet açısından istatistik olarak anlamlı bir farklılık (p<0.001) bulundu.
Sonuç: Toplamda 7815 kişi değerlendirildi. Hastaneye başvuran bireylerin %59.90’ı (4681 kişi) diabetes mellitusa yakalanma riskinin daha yüksek olduğu sonucuna varıldı. Diyabet hastalarında rutin olarak HOMA-IR testinin yapılması önerildi. Bu bulguların diyabetik olmayan hastalarda da bulunması kardiyovasküler mortalite riskini artıracağından daha yakın takip edilmesi gerektiği kanaatine varıldı.

Keywords

Diyabet, Hastalık riski, İnsülin direnci

Evaluation of HOMA-IR Values of Patients Applying to Sakarya Training and Research Hospital in Terms of Age and Gender Factor

Abstract

Aim: In this study, it was aimed to determine the HOMA-IR values of individuals who applied to different polyclinics of our hospital due to different ailments. This study was conducted to determine the insulin resistance of individuals.
Material and Method: In our study, insulin resistance parameters were recorded by analyzing the data of 7815 patients who applied to different polyclinics of our hospital. 7815 patients (1740 men, 6075 women) were evaluated as material. In this study, insulin resistance; it was measured by the homeostatic model evaluation (HOMA) method. Individuals with HOMA-IR scores ≥ 2.7 were considered to have insulin resistance.
Findings: The average age of patients who applied to different polyclinics of our hospital was calculated as 40.89 ± 0.16 years. 4681 (59.90%) of the patients were calculated to be insulin resistant. A statistically significant difference was found between the groups with and without insulin resistance in terms of age and gender (p <0.001).
Results: In total, 7815 people were evaluated. It was concluded that 59.90% (4681 people) of individuals who applied to the hospital had a higher risk of developing diabetes mellitus. Routine HOMA-IR testing was recommended for patients with diabetes. It was concluded that these findings should be followed up more closely since the presence of these findings in non-diabetic patients would increase the risk of cardiovascular mortality.

Keywords

Diabetes, Disease risk, Insulin resistance

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