Laboratory Diagnosis of COVID-19, a Review of Literature

Abstract

Devam etmekte olan COVID-19 pandemisi Dünya’daki tüm ülkeleri yaygın bir şekilde etkileyen bir sağlık problemidir. Hastalığın hızlı tanısındaki sorunlar da sağlık kuruluşlarının önemli endişelerinden biridir. Nazofarengeal ve alt solunum yolları örneklerinden yapılan NAAT (Nükleik asit amplifikasyon testleri) tanıda daha fazla özgüllüğe sahiptir; ancak, hâli hazırda devam etmekte olan pandemi sürecinde her şüphelenilen hastaya bu testleri uygulamak yoğunluk nedeniyle kolay değildir. Başvuru sırasında rutin olarak uygulanan bazı basit testler ciddi veya daha sonra ciddi olabilecek vakaların hastaneye yatırılması konusunda fikir verebilir. Bu derleme, klinisyenlerin hastaların tanı ve tedavi süreçlerini yönetiminde, pandemi yoğunluğunun ortasında hızlı ve isabetli karar vermelerine yardımcı olmak için nonspesifik testler ve COVID-19’un Mikrobiyolojik testlerine yoğunlaşmıştır. Ongoing COVID-19 pandemic outbreak is an emerging health issue affecting every country in the World. Problems at rapid diagnosis of the disease is also another important concern of health facilities. NAATs (Nucleic acid amplification tests) from nasopharyngeal and lower respiratory airway samples have more specifity at diagnosis; but the feasibility of sampling these tests for every suspected patients during ongoing pandemic outbreak is not easy due to intensity of hospitals. Routine simple tests on admission may give an idea about hospitalization of severe cases or cases who can be severe later. This review is focused on nonspecific and Microbiological tests of COVID-19 to help clinicians make decisions about management of diagnosis and treatment process of patients fastly and accurately in the middle of pandemic intensity.

Keywords

• RT-PCR,COVID-19,Diagnosis,Antibody Tests

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