Adölesan, Normal ve İleri Yaş Gebeliklerde Tiroid Fonksiyonlarının Değerlendirilmesi

Year 2021, Volume: 8 Issue: 1, 29 - 33, 30.04.2021

Mehmet Ferdi Kıncı Ezgi Karakaş Paskal Ercan Saruhan Yalçın Başaran

https://doi.org/10.47572/muskutd.732704

Abstract

Bu çalışmada, hastanemize başvuran gebe kadınların tiroid fonksiyon testi (fT4 veTSH) sonuçlarını ve bu sonuçlara göre hipertiroidi, ötiroidi, subklinik hipotiroidi ve aşikar hipotiroidi sıklığını yaş gruplarına göre değerlendirdik. Mevcut gebeliğinde ilk defa hastaneye başvuran birinci trimestrde olan 6843 gebe çalışmaya dahil edildi. Hastalar 19 yaş altı, 20-34 yaş arası ve 35 yaş üzeri şeklinde 3 gruba ayrıldı. fT4 ve TSH değerleri gruplar arasında karşılaştırıldı. Gebelerin ortalama TSH değerleri 1.61 (0.987, 2.41) mIU/mL’idi. Çalışma grupları arasında hipertiroidi, ötiroidi, subklinik hipotiroidi ve aşikar hipotiroidi açısından istatistiksel olarak anlamlı fark izlenmedi. Fakat, 35 yaş üzerindeki gebelerde hipertiroidi sıklığı 35 yaş altındaki gebelere göre daha fazla izlendi. Ülkemizdeki diğer çalışmalara benzer şekilde sırası ile; hipertiroidi, subklinik hipotiroidi ve aşikar hipotiroidi sıklığı %2.9, %22.1 ve %0.4 olarak saptanmıştır. Bu nedenle, özellikle ülkemiz gibi iyot eksikliği sık olan bölgelerde yaş ayrımı gözetmeksizin gebelerde tiroid fonksiyonlarının çalışılmasını öneriyoruz.

Keywords

Gebelik, Hipotiroidi, TSH, Tiroid Fonksiyonu

Evaluation of the Thyroid Functions in Adolescent, Normal and Advanced Age Pregnancies

Abstract

We aimed to investigate the thyroid function test (fT4 and TSH) results and the prevalence of hyperthyroidism, euthyroidism, subclinical hypothyroidism, and overt hypothyroidism according to age groups in pregnant women who had applied to our hospital. Six thousand eight hundred and fourty-three pregnant women who were in the first trimester and who applied to the hospital for the first time in their current pregnancy were included in the study. Patients were divided into 3 age groups, namely, ≤19 years, 20-34 years, and ≥35 years. The fT4 and TSH levels were compared between the age groups. The mean serum TSH value of patients was 1.61(0.987, 2.41) mIU/mL. There was no statistically significant difference in the rates of hyperthyroidism, euthyroidism, subclinical hypothyroidism and overt hypothyroidism between the three age groups. However, the incidence of hyperthyroidism in pregnant women aged 35 years and older was significantly higher when compared with those aged 35 years and younger. Consistently with the previous studies in our country, the prevalence of hyperthyroidism, subclinical hypothyroidism and overt hypothyroidism was detected as 2.9%, 22.1%, and 0.4%, respectively. Therefore, we recommend regular thyroid testing in pregnancy regardless of age, especially in countries where iodine deficiency is common.

Keywords

Hypothyroidism, Pregnancy, TSH, Thyroid Function

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