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Removed Stomach After Sleeve Gastrectomy: Is Routine Pathological Examination Necessary?

Year 2022, Volume: 9 Issue: 2, 169 - 173, 24.08.2022
https://doi.org/10.47572/muskutd.949327

Abstract

Laparoscopic sleeve gastrectomy is the most commonly used method in bariatric surgery. The aim of this study is to examine the histopathological findings frequently encountered in the pathological examination of the stomach removed after the sleeve gastrectomy procedure, which is preferred in the surgical treatment of obesity, and to discuss the necessity of routine pathological evaluation of removed stomach. The files of 102 consecutive patients who underwent sleeve gastrectomy between January 2017 and December 2020 were analyzed retrospectively. In the pathological examination, pathologies other than the normal gastric mucosa were evaluated in terms of the severity of inflammation, activity, presence of atrophy, intestinal metaplasia, helicobacter pylori (HP) positivity, and abnormal histopathological findings. The mean age of the patients, the majority of whom were women (n=79, 77.5%), was 43.2±12.0 (16-69). Mean preoperative body weight was 128.0±16.8 kg; mean body mass index was determined as 46.7±8.4. There was no malignant or premalignant lesion that would change the treatment modality, such as dysplasia or metaplasia, in any of the patients. Preoperative endoscopy is important both to find a pathological diagnosis and to determine reflux. We support the opinion that if a pathology is observed in the intraoperative macroscopic examination, the specimen should be submitted for histopathological examination.

References

  • 1. World Health Organization. Obesity and overweight. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
  • 2. T.C Sağlık Bakanlığı. Türkiye Beslenme ve Sağlık Araştırması 2010. Available from: https://hsgm.saglik.gov.tr/depo/birimler/saglikli-beslenme-hareketli-hayat-db/Yayinlar/kitaplar/diger-kitaplar/TBSA-Beslenme-Yayini.pdf.
  • 3. Hirth DA, Jones EL, Rothchild KB, ve ark. Laparoscopic sleeve gastrectomy: long-term weight loss outcomes. Surgery for obesity and related diseases. Surgery for Obesity and Related Diseases. 2015;11(5):1004-7.
  • 4. T.C Sağlık Bakanlığı. Ülkemizdeki sağlık hizmeti sunumunda patoloji uzmanlık alanının durumu ve öneriler (strateji raporu). Available from: https://www.researchgate.net/publication/334683838_ULKEMIZDEKI_SAGLIK_HIZMETI_SUNUMUNDA_PATOLOJI_UZMANLIK_ALANININ_DURUMU_VE_ONERILER_STRATEJI_PAPORU.
  • 5. Ben-David K, Rossidis G. Bariatric surgery: indications, safety and efficacy. Curr Pharm Des. 2011;17(12):1209-17.
  • 6. Gluck B, Movitz B, Jansma S, ve ark. Laparoscopic sleeve gastrectomy is a safe and effective bariatric procedure for the lower BMI (35.0-43.0 kg/m2) population. Obes Surg. 2011;21(8):1168-71.
  • 7. Gajbhiye R, Tirpude B, Bhanarkar H, ve ark. A study on role of laparoscopic sleeve gastrectomy in the management of morbid obesity. Indian J Surg. 2016;78(3):177-81.
  • 8. Clapp B. Histopathologic findings in the resected specimen of a sleeve gastrectomy. JSLS. 2015;19(1):e2013.00259.
  • 9. Al Saady R, Ejeckam G. Histopathological findings in laparoscopic sleeve gastrectomy specimens. Qatar Med J. 2019;2019(1):5.
  • 10. Ohanessian SE, Rogers AM, Karamchandani DM. Spectrum of gastric histopathologies in severely obese american patients undergoing sleeve gastrectomy. Obes Surg. 2016;26(3):595-602.
  • 11. Almazeedi S, Al-Sabah S, Al-Mulla A, ve ark. Gastric histopathologies in patients undergoing laparoscopic sleeve gastrectomies. Obes Surg. 2013;23(3):314-9.
  • 12. Miller GC, Reid AS, Brown IS. The pathological findings seen in laparoscopic sleeve gastrectomies for weight loss. Pathology. 2016;48(3):228-32.
  • 13. Safaan T, Bashah M, El Ansari W, ve ark. Histopathological changes in laparoscopic sleeve gastrectomy specimens: prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017;27(7):1741-9.
  • 14. Ge L, Moon RC, Nguyen H, ve ark. Pathologic findings of the removed stomach during sleeve gastrectomy. Surg Endosc. 2019;33(12):4003-7.
  • 15. Dogan U, Suren D, Oruc MT, ve ark. Spectrum of gastric histopathologies in morbidly obese Turkish patients undergoing laparoscopic sleeve gastrectomy. Eur Rev Med Pharmacol Sci. 2017;21(23):5430-6.
  • 16. Yardimci E, Bozkurt S, Baskoy L, ve ark. Rare entities of histopathological findings in 755 sleeve gastrectomy cases: A synopsis of preoperative endoscopy findings and histological evaluation of the specimen. Obes Surg. 2018;28(5):1289-95.
  • 17. Nowak K, Di Palma A, Chieu K, ve ark. Histologic and cost-benefit analysis of laparoscopic sleeve gastrectomy specimens performed for morbid obesity. Arch Pathol Lab Med. 2021;145(3):365-70.
  • 18. Komaei I, Currò G, Mento F, ve ark. Gastric histopathologic findings in south italian morbidly obese patients undergoing laparoscopic sleeve gastrectomy: Is histopathologic examination of all resected gastric specimens necessary? Obes Surg. 2020;30(4):1339-46.
  • 19. Canil AM, Iossa A, Termine P, ve ark. Histopathology findings in patients undergoing laparoscopic sleeve gastrectomy. Obes Surg. 2018;28(6):1760-5.
  • 20. Hansen SK, Pottorf BJ, Hollis HW, Jr., ve ark. Is it necessary to perform full pathologic review of all gastric remnants following sleeve gastrectomy? Am J Surg. 2017;214(6):1151-5.
  • 21. Uguen A, Guibourg B, Badic B, ve ark. Reasons for pathologic examination of sleeve gastrectomy remnants in France. Am J Surg. 2018;216(5):1031-2.
  • 22. Walędziak M, Różańska-Walędziak A, Kowalewski PK, ve ark. Bariatric surgery and incidental gastrointestinal stromal tumors - a single-center study: VSJ Competition, 1(st) place. Wideochir Inne Tech Maloinwazyjne. 2017;12(3):325-9.

Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?

Year 2022, Volume: 9 Issue: 2, 169 - 173, 24.08.2022
https://doi.org/10.47572/muskutd.949327

Abstract

Laparoskopik sleeve gastrektomi, obezite cerrahisinde en sık kullanılan yöntemdir. Bu çalışmanın amacı obezitenin cerrahi tedavisinde tercih edilen sleeve gastrektomi prosedürü sonrasında çıkarılan midenin patolojik incelemesinde sıklıkla karşılaşılan histopatolojik bulguları incelemek ve çıkarılan bu parçaların rutin patolojik değerlendirme gerekliliğini tartışmaktır. Ocak 2017 ile Aralık 2020 tarihleri arasında sleeve gastrektomi uygulanan ardışık 102 hastanın dosyası retrospektif olarak analiz edildi. Patolojik incelemede normal gastrik mukoza dışındaki patolojiler inflamasyonun şiddeti, aktivitesi, atrofi varlığı, intestinal metaplazi, helikobakter pilori (HP) pozitifliği ve anormal histopatolojik bulgular yönünden değerlendirildi. Büyük çoğunluğu kadın olan (n=79, %77.5) hastaların yaş ortalaması 43.2±12.0 (16-69) idi. Ortalama preoperatif vücut ağırlıkları 128.0±16.8 kg; vücut kitle indeksleri ise 46.7±8.4 olarak belirlendi. Hiçbir hastada displazi veya metaplazi gibi tedavi modalitesini değiştirecek malign ya da premalign lezyona rastlanmadı. Preoperatif endoskopi hem patolojik bir tanının bulunabilmesi hem de reflünün belirlenmesi için önemlidir. İntraoperatif yapılacak olan makroskopik incelemede bir patoloji görülmesi halinde, piyesin histopatolojik incelemeye iletilmesi gerektiği kanaatini destekliyoruz. 

References

  • 1. World Health Organization. Obesity and overweight. Available from: https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
  • 2. T.C Sağlık Bakanlığı. Türkiye Beslenme ve Sağlık Araştırması 2010. Available from: https://hsgm.saglik.gov.tr/depo/birimler/saglikli-beslenme-hareketli-hayat-db/Yayinlar/kitaplar/diger-kitaplar/TBSA-Beslenme-Yayini.pdf.
  • 3. Hirth DA, Jones EL, Rothchild KB, ve ark. Laparoscopic sleeve gastrectomy: long-term weight loss outcomes. Surgery for obesity and related diseases. Surgery for Obesity and Related Diseases. 2015;11(5):1004-7.
  • 4. T.C Sağlık Bakanlığı. Ülkemizdeki sağlık hizmeti sunumunda patoloji uzmanlık alanının durumu ve öneriler (strateji raporu). Available from: https://www.researchgate.net/publication/334683838_ULKEMIZDEKI_SAGLIK_HIZMETI_SUNUMUNDA_PATOLOJI_UZMANLIK_ALANININ_DURUMU_VE_ONERILER_STRATEJI_PAPORU.
  • 5. Ben-David K, Rossidis G. Bariatric surgery: indications, safety and efficacy. Curr Pharm Des. 2011;17(12):1209-17.
  • 6. Gluck B, Movitz B, Jansma S, ve ark. Laparoscopic sleeve gastrectomy is a safe and effective bariatric procedure for the lower BMI (35.0-43.0 kg/m2) population. Obes Surg. 2011;21(8):1168-71.
  • 7. Gajbhiye R, Tirpude B, Bhanarkar H, ve ark. A study on role of laparoscopic sleeve gastrectomy in the management of morbid obesity. Indian J Surg. 2016;78(3):177-81.
  • 8. Clapp B. Histopathologic findings in the resected specimen of a sleeve gastrectomy. JSLS. 2015;19(1):e2013.00259.
  • 9. Al Saady R, Ejeckam G. Histopathological findings in laparoscopic sleeve gastrectomy specimens. Qatar Med J. 2019;2019(1):5.
  • 10. Ohanessian SE, Rogers AM, Karamchandani DM. Spectrum of gastric histopathologies in severely obese american patients undergoing sleeve gastrectomy. Obes Surg. 2016;26(3):595-602.
  • 11. Almazeedi S, Al-Sabah S, Al-Mulla A, ve ark. Gastric histopathologies in patients undergoing laparoscopic sleeve gastrectomies. Obes Surg. 2013;23(3):314-9.
  • 12. Miller GC, Reid AS, Brown IS. The pathological findings seen in laparoscopic sleeve gastrectomies for weight loss. Pathology. 2016;48(3):228-32.
  • 13. Safaan T, Bashah M, El Ansari W, ve ark. Histopathological changes in laparoscopic sleeve gastrectomy specimens: prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017;27(7):1741-9.
  • 14. Ge L, Moon RC, Nguyen H, ve ark. Pathologic findings of the removed stomach during sleeve gastrectomy. Surg Endosc. 2019;33(12):4003-7.
  • 15. Dogan U, Suren D, Oruc MT, ve ark. Spectrum of gastric histopathologies in morbidly obese Turkish patients undergoing laparoscopic sleeve gastrectomy. Eur Rev Med Pharmacol Sci. 2017;21(23):5430-6.
  • 16. Yardimci E, Bozkurt S, Baskoy L, ve ark. Rare entities of histopathological findings in 755 sleeve gastrectomy cases: A synopsis of preoperative endoscopy findings and histological evaluation of the specimen. Obes Surg. 2018;28(5):1289-95.
  • 17. Nowak K, Di Palma A, Chieu K, ve ark. Histologic and cost-benefit analysis of laparoscopic sleeve gastrectomy specimens performed for morbid obesity. Arch Pathol Lab Med. 2021;145(3):365-70.
  • 18. Komaei I, Currò G, Mento F, ve ark. Gastric histopathologic findings in south italian morbidly obese patients undergoing laparoscopic sleeve gastrectomy: Is histopathologic examination of all resected gastric specimens necessary? Obes Surg. 2020;30(4):1339-46.
  • 19. Canil AM, Iossa A, Termine P, ve ark. Histopathology findings in patients undergoing laparoscopic sleeve gastrectomy. Obes Surg. 2018;28(6):1760-5.
  • 20. Hansen SK, Pottorf BJ, Hollis HW, Jr., ve ark. Is it necessary to perform full pathologic review of all gastric remnants following sleeve gastrectomy? Am J Surg. 2017;214(6):1151-5.
  • 21. Uguen A, Guibourg B, Badic B, ve ark. Reasons for pathologic examination of sleeve gastrectomy remnants in France. Am J Surg. 2018;216(5):1031-2.
  • 22. Walędziak M, Różańska-Walędziak A, Kowalewski PK, ve ark. Bariatric surgery and incidental gastrointestinal stromal tumors - a single-center study: VSJ Competition, 1(st) place. Wideochir Inne Tech Maloinwazyjne. 2017;12(3):325-9.
There are 22 citations in total.

Details

Primary Language Turkish
Subjects Surgery
Journal Section Original Article
Authors

Emin Lapsekili 0000-0001-5910-1154

Ümit Alakuş This is me 0000-0002-6756-3583

Publication Date August 24, 2022
Submission Date October 5, 2021
Published in Issue Year 2022 Volume: 9 Issue: 2

Cite

APA Lapsekili, E., & Alakuş, Ü. (2022). Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 9(2), 169-173. https://doi.org/10.47572/muskutd.949327
AMA Lapsekili E, Alakuş Ü. Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?. MMJ. August 2022;9(2):169-173. doi:10.47572/muskutd.949327
Chicago Lapsekili, Emin, and Ümit Alakuş. “Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli Mi?”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9, no. 2 (August 2022): 169-73. https://doi.org/10.47572/muskutd.949327.
EndNote Lapsekili E, Alakuş Ü (August 1, 2022) Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9 2 169–173.
IEEE E. Lapsekili and Ü. Alakuş, “Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?”, MMJ, vol. 9, no. 2, pp. 169–173, 2022, doi: 10.47572/muskutd.949327.
ISNAD Lapsekili, Emin - Alakuş, Ümit. “Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli Mi?”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9/2 (August 2022), 169-173. https://doi.org/10.47572/muskutd.949327.
JAMA Lapsekili E, Alakuş Ü. Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?. MMJ. 2022;9:169–173.
MLA Lapsekili, Emin and Ümit Alakuş. “Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli Mi?”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, vol. 9, no. 2, 2022, pp. 169-73, doi:10.47572/muskutd.949327.
Vancouver Lapsekili E, Alakuş Ü. Sleeve Gastrektomi Sonrası Çıkarılan Gastrektomi Materyali: Patolojik İnceleme Gerekli mi?. MMJ. 2022;9(2):169-73.