Case Report
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Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report

Year 2022, Volume: 9 Issue: 3, 304 - 308, 30.12.2022
https://doi.org/10.47572/muskutd.978712

Abstract

Squamous cell carcinoma (SCC) is the second most common skin cancer and it often occurs in sun-exposed areas such as head and neck skin. Invasive SCC located on breast skin is a rare entity and may clinically mimic breast cancer. We report a case of a 39 years old female with a non-eroded, vegetative, growing lesion on the right breast skin, initially mimicking breast cancer both clinically and histopathologically. After surgery with clear margins, adjuvant radiotherapy was administered, by considering the pathological risk factors for recurrence. At 14 months, the patient is disease-free and under regular follow-up. Invasive SCC of the breast skin is a rare entity and may have different etiology/behavior or directly develop de novo when compared to SCCs located on sun-exposed skin. Medical history and physical examination in conjunction with histopathological examination of the biopsy specimen are critical for the accuracy of the diagnosis and the correct treatment decision in patients presenting with a mass invading breast skin.

References

  • 1. Que SKT, Zwald FO, Schmults CD. Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol. 2018;78(2):237-47.
  • 2. Melo Neto B, Oliveira Gda P, Vieira SC, Leal LR, Melo Junior JA, Vieira CF. Epidermoid carcinoma of the skin mimicking breast cancer. An Bras Dermatol. 2013;88(2):250-2.
  • 3. Cherpelis BS, Marcusen C, Lang PG. Prognostic factors for metastasis in squamous cell carcinoma of the skin. Dermatol Surg. 2002;28(3):268-73.
  • 4. Alam M, Ratner D. Cutaneous squamous-cell carcinoma. N Engl J Med. 2001;344(13):975-83.
  • 5. Work G, Invited R, Kim JYS, Kozlow JH, Mittal B, Moyer J, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol. 2018;78(3):560-78.

Meme Kanserini Taklit Eden Cilt Skuamöz Hücreli Karsinomu: Vaka Raporu

Year 2022, Volume: 9 Issue: 3, 304 - 308, 30.12.2022
https://doi.org/10.47572/muskutd.978712

Abstract

Skuamöz hücreli karsinomu (SHK), 2. en sık cilt kanseridir ve sıklıkla baş- boyun gibi güneş gören bölgelerde ortaya çıkar. Meme cildinden kaynaklanan invazif SHK nadir bir tablodur ve klinik olarak meme kanserini taklit edebilir. 39 yaşındaki hastada; sağ memede non-erode, vejetatif, büyüyen lezyondan biyopsi alınmıştır ve klinik ve histopatolojik olarak meme kanserini taklit eden bu vaka sunulmuştur. Cerrahi sınırları temiz bir şekilde opere edilen hasta, rekürrens için risk faktörleri değerlendirilerek, adjuvant radyoterapi ile tedavi edilmiştir. 14 ay sonrasında, hastada halen nüks saptanmamış ve düzenli takiplerdedir. İnvazif meme cilt SHK’u nadir bir tablodur ve güneşe maruz kalan bölgede gelişen SHK’a göre farklı etiyoloji/ davranışa sahip olabilir. Meme cildinde kitle ile başvuran hastanın doğru tanı ve tedavisi için tıbbi hikaye ve fizik muayene ile birlikte histopatolojik değerlendirme kritiktir.

References

  • 1. Que SKT, Zwald FO, Schmults CD. Cutaneous squamous cell carcinoma: Incidence, risk factors, diagnosis, and staging. J Am Acad Dermatol. 2018;78(2):237-47.
  • 2. Melo Neto B, Oliveira Gda P, Vieira SC, Leal LR, Melo Junior JA, Vieira CF. Epidermoid carcinoma of the skin mimicking breast cancer. An Bras Dermatol. 2013;88(2):250-2.
  • 3. Cherpelis BS, Marcusen C, Lang PG. Prognostic factors for metastasis in squamous cell carcinoma of the skin. Dermatol Surg. 2002;28(3):268-73.
  • 4. Alam M, Ratner D. Cutaneous squamous-cell carcinoma. N Engl J Med. 2001;344(13):975-83.
  • 5. Work G, Invited R, Kim JYS, Kozlow JH, Mittal B, Moyer J, et al. Guidelines of care for the management of cutaneous squamous cell carcinoma. J Am Acad Dermatol. 2018;78(3):560-78.
There are 5 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Report
Authors

Görkem Türkkan This is me 0000-0002-9084-2599

Furkan Gözübüyük This is me 0000-0002-5030-8228

Kutluhan Çınbay 0000-0002-9164-4519

Emine Erva Özen This is me 0000-0002-1342-6858

Fatih Özdemir This is me 0000-0003-3237-6718

Ali Alkan 0000-0002-8253-5046

Melek Ünçel 0000-0002-0304-2682

Ferda Bacakszılar Sarı 0000-0002-6293-9481

Leyla Tekin 0000-0003-1172-5536

Funda Dinç Elibol 0000-0002-3979-4413

Özcan Dere 0000-0002-5589-4326

Gülnihan Eren Kupık 0000-0002-3315-3893

Özgür Tanrıverdi 0000-0002-0598-7284

Okay Nazlı 0000-0001-8500-5510

Publication Date December 30, 2022
Submission Date December 29, 2021
Published in Issue Year 2022 Volume: 9 Issue: 3

Cite

APA Türkkan, G., Gözübüyük, F., Çınbay, K., Özen, E. E., et al. (2022). Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, 9(3), 304-308. https://doi.org/10.47572/muskutd.978712
AMA Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. December 2022;9(3):304-308. doi:10.47572/muskutd.978712
Chicago Türkkan, Görkem, Furkan Gözübüyük, Kutluhan Çınbay, Emine Erva Özen, Fatih Özdemir, Ali Alkan, Melek Ünçel, Ferda Bacakszılar Sarı, Leyla Tekin, Funda Dinç Elibol, Özcan Dere, Gülnihan Eren Kupık, Özgür Tanrıverdi, and Okay Nazlı. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9, no. 3 (December 2022): 304-8. https://doi.org/10.47572/muskutd.978712.
EndNote Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O (December 1, 2022) Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9 3 304–308.
IEEE G. Türkkan, “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”, MMJ, vol. 9, no. 3, pp. 304–308, 2022, doi: 10.47572/muskutd.978712.
ISNAD Türkkan, Görkem et al. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi 9/3 (December 2022), 304-308. https://doi.org/10.47572/muskutd.978712.
JAMA Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. 2022;9:304–308.
MLA Türkkan, Görkem et al. “Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report”. Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi, vol. 9, no. 3, 2022, pp. 304-8, doi:10.47572/muskutd.978712.
Vancouver Türkkan G, Gözübüyük F, Çınbay K, Özen EE, Özdemir F, Alkan A, Ünçel M, Bacakszılar Sarı F, Tekin L, Dinç Elibol F, Dere Ö, Eren Kupık G, Tanrıverdi Ö, Nazlı O. Squamous Cell Carcinoma of The Skin Mimicking Breast Cancer: A Case Report. MMJ. 2022;9(3):304-8.