Bibliometric Analysis of Studies on the Energy Metabolism Enzyme Isocitrate Dehydrogenase

Abstract

Objective: Isocitrate dehydrogenase (IDH) is an important enzyme involved in the Krebs cycle and cellular energy metabolism. It is stated to be a prognostic, diagnostic, and therapeutic target in many cancer types. This makes the IDH enzyme a popular subject of scientific research. This current study aimed to examine the IDH molecule in the WoS database using bibliometric indicators, evaluate the studies conducted in Turkey, and determine the place of traditional medicine in IDH studies. Materials and Methods: "IDH", "Isocitrate dehydrogenase", and “traditional medicine” keywords were used for search in the WoS database. This search was performed in the abstract, title, and keywords. The "Article" option was used to access the data of original research articles published between 1980-2022. Results: A total of 9.103 research articles were reached by the end of 2022 among 11.982 publications. It has been determined that there has been an increase in the number of studies in recent years, the highest number of articles were published in 2021 (n=995), the most used language was English with 98,363%, the most productive country was the USA with 2.696 studies, and Turkey ranked 23rd with 97 studies. It has been determined that 16 research articles about traditional medicine have been published. Conclusion: IDH is a current research topic. However, studies on traditional medicine about IDH are very few. More research should be done and more articles should be published for the studies from Turkey to take place in the international rankings on this current topic.

Keywords

• IDH
• WoS
• Bibliometry
• Traditional Medicine

Enerji Metabolizması Enzimlerinden İzositrat Dehidrogenazla İlgili Çalışmaların Bibliyometrik Analizi

Abstract

Amaç: İzositrat dehidrogenaz (IDH), krebs döngüsünde ve hücresel enerji metabolizmasında yer alan önemli bir enzimdir. Birçok kanser türünde prognostik, diyagnostik ve terapötik bir hedef olduğu belirtilmektedir. Bu durum IDH enzimini popüler bir çalışma konusu haline getirmektedir. Bu çalışmada da, IDH molekülünün bibliyometrik göstergeler kullanılarak WoS veri tabanında incelenmesi, yapılan çalışmaların Türkiye ölçeğinde değerlendirilmesi ve geleneksel tıbbın bu çalışmalardaki yerinin belirlenmesi amaçlanmıştır. Yöntem: WoS veri tabanında “IDH”, “Isocitrate dehydrogenase” ve “traditional medicine” anahtar kelimeleri ile tarama yapılmıştır. Bu taramada özet, başlık ve anahtar kelimelerde arama gerçekleştirilmiş, 1980-2022 yılları arasında yayınlanmış orijinal araştırma makalelerinin verilerine erişebilmek için “Article” seçeneği kullanılmıştır. Bulgular: Konuyla ilgili 11.982 yayın içerisinde 2022 yılının sonuna kadar toplamda 9.103 araştırma makalesine ulaşılmıştır. Son yıllarda çalışma sayılarında artış olduğu, en fazla sayıda makalenin 2021 yılında yayınlandığı (n=995), en çok kullanılan dilin %98,363 ile İngilizce olduğu, en üretken ülkenin 2.696 çalışmayla ABD olduğu, Türkiye’nin 97 çalışmayla 23. sırada yer aldığı tespit edilmiştir. Geleneksel tıpla ilgili 16 araştırma makalesinin yayınlandığı belirlenmiştir. Sonuç: IDH günümüzde güncel bir çalışma konusudur. Buna rağmen, geleneksel tıpla ilgili çalışmalar ise çok az sayıdadır. Türkiye adresli çalışmaların bu güncel konuyla ilgili uluslararası sıralamalardaki yerini daha yukarılara taşıyabilmesi için daha çok çalışmanın yapılması ve makalenin yayınlanması gerekmektedir.

Keywords

• IDH
• WoS
• Bibliyometri
• Geleneksel Tıp

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