Global Collaborations in SREBP Research: Scientific Productivity and Impact

Abstract

Aim: This study provides a comprehensive bibliometric analysis of SREBP research, assessing its scientific impact and evolution over time. Background: Sterol regulatory element-binding proteins (SREBPs) are transcription factors regulating lipid synthesis and uptake. They play vital roles in lipogenesis, endoplasmic reticulum stress, inflammation, autophagy, and apoptosis. Methods: We analyzed original research articles published from 1997 to 2023 using the Web of Science Core Collection database. Data analysis was performed using VOSviewer, Bibliometrix, Biblioshiny, and Microsoft Excel, examining publication outputs, countries, institutions, journals, authors, keywords, and citations. Results: A total of 3,863 articles were identified, authored by 13,910 researchers. The most productive countries were China, the USA, and South Korea, with the USA leading in total citations. Seoul National University and Nanjing Agricultural University were identified as key institutions. The analysis revealed significant global collaborations and emphasized SREBP’s impact on metabolic diseases and cancer biology. Conclusion: This bibliometric analysis offers valuable insights into SREBP research, identifying leading contributors, trends, and future research directions. It serves as a guide for researchers in selecting appropriate journals, collaborators, and focus areas.

Keywords

• SREBP
• bibliometric analysis
• lipid metabolism
• transcription factors
• VOSviewer

SREBP Araştırmalarında Küresel İşbirlikleri: Bilimsel Üretkenlik ve Etki

Abstract

Amaç: Bu çalışma, SREBP araştırmalarının bilimsel etkisini ve zaman içindeki gelişimini değerlendiren kapsamlı bir bibliyometrik analiz sunmaktadır. Sterol düzenleyici element bağlayıcı proteinler (SREBP'ler) lipit sentezini ve alımını düzenleyen transkripsiyon faktörleridir. Lipogenez, endoplazmik retikulum stresi, inflamasyon, otofaji ve apoptozda hayati rol oynarlar. Yöntem: Web of Science Core Collection veri tabanını kullanarak 1997'den 2023'e kadar yayınlanmış orijinal araştırma makalelerini analiz ettik. Veri analizi VOSviewer, Bibliometrix, Biblioshiny ve Microsoft Excel kullanılarak gerçekleştirilmiş ve yayın çıktıları, ülkeler, kurumlar, dergiler, yazarlar, anahtar kelimeler ve atıflar incelenmiştir. Bulgular: 13.910 araştırmacı tarafından yazılmış toplam 3.863 makale tespit edilmiştir. En üretken ülkeler Çin, ABD ve Güney Kore olurken, toplam atıflarda ABD başı çekmiştir. Seul Ulusal Üniversitesi ve Nanjing Tarım Üniversitesi kilit kurumlar olarak belirlenmiştir. Analiz, önemli küresel işbirliklerini ortaya çıkarmış ve SREBP'nin metabolik hastalıklar ve kanser biyolojisi üzerindeki etkisini vurgulamıştır. Sonuç: Bu bibliyometrik analiz, SREBP araştırmalarına ilişkin değerli bilgiler sunmakta, önde gelen katkıda bulunanları, eğilimleri ve gelecekteki araştırma yönlerini belirlemektedir. Araştırmacılar için uygun dergileri, işbirlikçileri ve odak alanlarını seçmede bir rehber görevi görmektedir.

Keywords

• SREBP
• bibliometric analysis
• lipid metabolism
• transcription factors
• VOSviewer
• Bibliometrix

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