The Use Of St. John’s Wort In Menopausal Symptom Management: A Systematic Review

Abstract

Aim: The study aimed to investigate the effect of St. John’s wort on menopausal symptoms.

Method: This study is a systematic review and was conducted between 17 December 2018-3 January 2019 by searching Turkish and English indexes. Ulakbim, Turk Medline, Google Academic and National Thesis Centre, Web of Science, PubMed (including MEDLINE), Cochrane and EBSCOhost database were searched by using “Menopause, climacterium, St. John's wort, Hypericum perforatum, menopause and St. John's wort, menopause and St John’s wort, menopause and Hypericum perforatum, climacterium and St. John's wort, climacterium and Hypericum perforatum”as keywords.  

Results: In this research, a total of 602 records were reached, and seven researches were analysed with 819 women, three of which examined the effect of the use of the St. John’s wort singly and four in combination with different herbs on menopausal symptoms. In two of the three studies using the St. John’s wort singly, this plant has been reported to be effective in reducing vasomotor symptoms, sleeping problems, depression/fatigue in two. In three of four studies used in combination of plant, was reported to be effective in reducing vasomotor symptoms, both anxiety and depression in two, and in one, it had no effect on vaginal dryness and loss of libido.

Conclusion: In this systematic review, it has been concluded that the use of St. John's wort singly or in combination is effective in reducing some menopausal symptoms, but further experimental studies are needed.

Keywords

• hypericum,menopause,complementary therapies

Menopozal Semptom Yönetiminde Sarı Kantaron Kullanımı: Sistematik Derleme

Abstract

Amaç: Bu araştırma, menopoz döneminde kullanılan sarı kantaron bitkisinin menopozal semptomlara etkisini incelemek amacı ile yapılmıştır.

Yöntem: Sistematik derleme niteliğinde olan çalışma, 17 Aralık 2018-3 Ocak 2019 tarihleri arasında, Türkçe ve İngilizce dizinler taranarak yapılmıştır. Ulakbim, Türk Medline, Google Akademik ve Ulusal Tez Merkezi Web of Science, PubMed (including MEDLINE), Cochrane ve EBSCOhost veri tabanları, “menopoz, klimakteriyum, sarı kantaron, St John’s wort, Hypericum perforatum, menopoz ve sarı kantaron,  menopoz ve St John’s wort, menopoz ve Hypericum perforatum, klimakteriyum ve sarı kantaron, klimakteriyum ve St John’s wort, klimakteriyum ve Hypericum perforatum” anahtar kelimeleri ile taranmıştır.

Bulgular: Çalışmada toplam 602 kayda ulaşılmış olup, üçü sarı kantaronun tek başına, dördü farklı bitkilerle bir arada kullanımının menopozal semptomlara etkisini inceleyen, toplam 819 kadın ile yapılan dokuz araştırma analize alınmıştır. Sarı kantaronun tek başına kullanıldığı beş çalışmadan ikisinde, bu bitkinin vazomotor semptomları, ikisinde uyku sorunlarını, depresyon ve yorgunluğu azaltmada etkili olduğu bildirilmiştir. Bitkinin kombine kullanıldığı dört çalışmadan üçünde kombinasyonun vazomotor semptomları, ikisinde anksiyete ve depresyonu azaltmada etkili olduğu, birinde ise vajinal kuruluk ve libido kaybı üzerinde herhangi bir etkisinin olmadığı bildirilmiştir.

Sonuç: Bu sistematik derlemede sarı kantaronun tek başına ya da kombine kullanımının bazı menopozal semptomları azaltmada etkili olduğu, ancak bu konuda daha fazla deneysel çalışmaya gereksinim bulunduğu sonucuna varılmıştır.

Anahtar Kelimeler: sarı kantaron (hypericum), , tamamlayıcı tedaviler

Keywords

• sarı kantaron (hypericum),menopoz,tamamlayıcı tedaviler

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