Synthesis and Characterization of Cellulose Based Injectable Polyurethane Gels

Year 2023, , 29 - 36, 30.06.2023

Fatma Bilge Emre , Fadime Nülüfer Kıvılcım

https://doi.org/10.46572/naturengs.1298413

Abstract

This article describes the synthesis and characterization of cellulose-based injectable polyurethane gels for tissue engineering applications. The gels were prepared by combining a cellulose derivative with a polyurethane precursor and crosslinking agent to form a stable gel under physiological conditions. The resulting gels were evaluated for swelling behavior.
The addition of cellulose to polyurethane is a promising approach to improve the properties of polyurethane. Cellulose is an abundant, environmentally friendly and inexpensive polysaccharide polymer widely used in hydrogels, pharmaceuticals and agriculture. The obtained cellulose-based polyurethane composites were characterized in detail using various techniques such as Fourier transform infrared spectroscopy (FTIR), Thermogravimetric Analyzer (TGA), Differential Scanning Calorimeter (DSC), Differential Thermal Analysis (DTA), swelling test measurements and optical microscopy. The results showed that the obtained composites are suitable for the production of injectable insulating materials. The paper also briefly discusses the various uses of polyurethanes in different fields, including furniture manufacturing, medical devices such as hospital beds, catheters, injection-coated devices, wound dressings and surgical dressings, as well as marine, air and land vehicles. In conclusion, this paper provides valuable insights into the development of cellulose-based injectable polyurethane gels for tissue engineering applications and highlights the potential of cellulose as an additive to enhance the properties of polyurethane. The results of this study may contribute to the development of new and improved biomaterials for tissue engineering applications.

Keywords

Polyurethanes, Cellulose, Injectable, Gels.

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