KANSER HASTALARINDA UYKU KALİTESİNİ ETKİLEYEN FAKTÖRLER

Year 2020, , 138 - 144, 23.08.2020

Nilay Şengül Samancı , Emir Celik , Ezgi Degerli , Melih Kasap , Kerem Oruc , Sahin Bedir , Sumeyra Derin , Nihan Senturk , Burc Poyraz , Zeynep Turna , Fuat Demirelli

https://doi.org/10.37696/nkmj.674879

Abstract

Objective: Sleep disorders are one of the most common problems in patients with malignancy and they severely decrease the quality of life. We ougt to investigate the frequency of sleep disturbances, its quantity, quality and possible correlation with related factors such as depression and anxiety.
Methods:150 patients participate and Pittsburgh Sleep Quality Index was used to evaluate the sleep quality. It is a self-administered questionnaire and standardized measure of sleep quality. Total score of ≥5 showes that quality of sleep is remarkably bad. Also a self-report measure of depression, the Beck Depression Inventory(BDI); and a self-report measure of anxiety, Beck Anxiety Inventory (BAI) were used.
Results: Of the 150 patients 74.0% has bad sleep quality (score >5 ). Mean PSQI total score was 7.34 (min 0-max 20). No difference was found between PSQI mean scores in terms of gender, radiotherapy (RT), chemotherapy (CHT), having chronic disease or having metastatic disease. NSAIDs and opioids were significantly correleted with PSQI (P<0.001). PSQI total scores are strongly associated with BDI score (r=.424 P<0.001) and BAI score (r=.417, P<0.001).
Conclusion: We found a high prevalence rate of bad sleep quality at 74%. Effective sleep treatment and psychological support should be provided in oncology clinics.
Sonuç: Sonuç olarak % 74 oranında yüksek bir kötü uyku kalitesi prevalans oranı bulduk. Bu da onkoloji kliniklerinde etkili uyku tedavisi ve psikolojik destek sağlanması gerektiğini ortaya koymaktadır.

Keywords

Beck Depresyon Envanteri, Pittsburgh Uyku Kalitesi Endeksi, Uyku Bozuklukları

FACTORS OF AFFECTING SLEEP QUALITY IN CANCER PATIENTS

Abstract

Objective: Sleep disorders are one of the most common problems in patients with malignancy and they severely decrease the quality of life. We ougt to investigate the frequency of sleep disturbances, its quantity, quality and possible correlation with related factors such as depression and anxiety.
Methods:150 patients participate and Pittsburgh Sleep Quality Index was used to evaluate the sleep quality. It is a self-administered questionnaire and standardized measure of sleep quality. Total score of ≥5 showes that quality of sleep is remarkably bad. Also a self-report measure of depression, the Beck Depression Inventory(BDI); and a self-report measure of anxiety, Beck Anxiety Inventory (BAI) were used.
Results: Of the 150 patients 74.0% has bad sleep quality (score >5 ). Mean PSQI total score was 7.34 (min 0-max 20). No difference was found between PSQI mean scores in terms of gender, radiotherapy (RT), chemotherapy (CHT), having chronic disease or having metastatic disease. NSAIDs and opioids were significantly correleted with PSQI (P<0.001). PSQI total scores are strongly associated with BDI score (r=.424 P<0.001) and BAI score (r=.417, P<0.001).
Conclusion: We found a high prevalence rate of bad sleep quality at 74%. Effective sleep treatment and psychological support should be provided in oncology clinics.

Keywords

Beck Depression Inventory, , Pittsburgh Sleep Quality Index, Sleep Disorders

References

• 1. Passik S.D, Whitcomb L.A, Kirsh K.L ,Theobald D.E. An unsuccessful attempt to develop a single-item screen for insomnia in cancer patients. Journal of Pain and Symptom Management 2003: 25; 284-7. 2. Steindorf K, Clauss D, Tjaden C, Hackert T, Herbolsheimer F, Bruckner T, et al. Quality of Life, Fatigue, and Sleep Problems in Pancreatic Cancer Patients—A Randomized Trial on the Effects of Exercise . Dtsch Arztebl Int. 2019 ;116:471-8. 3. Mollayeva T, Thurairajah P, Burton K, Mollayeva S, Shapiro CM, Colantonio A. The Pittsburgh sleep quality index as a screening tool for sleep dysfunction in clinical and non-clinical samples: A systematic review and meta-analysis. Sleep Med Rev. 2016 ;25:52-73. 4. Beck S.L, Schwartz A.L, Towsley G, Dudley W, Barsevick A. Psycho- metric evaluation of the Pittsburgh Sleep Quality Index in cancer patients. Journal of Pain and Symptom Management 2004 ;27:140-8. 5. de Kock I, Mirhosseini M, Lau F, Thai V, Downing M, Quan H, et al. Conversion of Karnofsky Performance Status (KPS) and Eastern Cooperative Oncology Group Performance Status (ECOG) to Palliative Performance Scale (PPS), and the interchangeability of PPS and KPS in prognostic tools. J Palliat Care. 2013 ;29:163-9. 6. Morris JL, Rohay J, Chasens ER. Sex Differences in the Psychometric Properties of the Pittsburgh Sleep Quality Index. J Womens Health (Larchmt). 2018 ;27 :278-82. 7. Wang YP, Gorenstein C. Psychometric properties of the Beck Depression Inventory- II: a comprehensive review. Braz J Psychiatry. 2013 ;35:416-31. 8. Julian LJ. Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care Res (Hoboken). 2011;63 :467-72. 9. Savard J, Laroche L, Simard S, Ivers H, Morin C.M. Chronic insomnia and immune functioning. Psychosomatic Medicine 2003; 65, 211-21. 10. Carpenter JS, Andrykowski MA. Psychometric evaluation of the Pittsburgh Sleep Quality Index. J Psychosom Res 1998;45: 5-13. 11. Forter BV, Stepanski EJ, Wang SC, Kasprowicz S, Durrence HH. Sleep and quality of life in breast cancer patients. J Pain Symptom Manage 2002;24: 471-80. 12. Savard J, Morin CM. Insomnia in the context of cancer: a review of a neglected problem. J Clin Oncol 2001; 19:895-908. 13. Davidson JR, MacLean AW, Brundage MD, Schulze K. Sleep disturbance in cancer patients. Soc Sci Med 2002;54: 1309-21. 14. Byles JE, Mishra GD, Harris MA. The experience of insomnia among older women. Sleep 2005;28: 972-9. 15. Greenberg D.B, Gray J.L, Mannix C.M, Eisenthal S, Carey M. Treatment-related fatigue and serum interleukin-1 levels in patients during external beam irradiation for prostate cancer. Journal of Pain and Symptom Management. 1993; 8 ; 196-200. 16. Theobald DE. Cancer pain, fatigue, distress, and insomnia in cancer patients. Clin Cornerstone 2004;6 ;15-21. 17. Murphy PJ, Badia P, Myers BL, Boecker MR, Wright KP Jr. Nonsteroidal anti-inflammatory drugs affect normal sleep patterns in humans. Physiol Behav. 1994;55:1063-6. 18. Roth T, Drake C. Evolution of insomnia: currents status and future direction. Sleep Med 2004;5: 23-30. 19. Buysse DJ. Insomnia, depression and aging Assessing sleep and mood interactions in older adults. Geriatrics 2004;59: 47-51. 20. Kuo H.H., Chiu M.J., Liao W.C., Hwang S.L. Quality of sleep and related factors during chemotherapy in patients with stage I/II breast cancer. Journal of the Formosan Medical Association. 2006; 105: 64-9.