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Dermatolojik açıdan labial füzyon: prospektif çalışma

Year 2019, Volume: 7 Issue: 3, 196 - 200, 18.12.2019

Abstract

Amaç:
Labial füzyon, prepubertal kızlarda sık görülen bir durumdur ve çeşitli
komplikasyonları vardır. Bazı dermatolojik durumlar bu hastalık için etiyolojik
faktör olarak bildirilmiştir. Bu çalışmanın amacı çocuklarda labial füzyonun etiyolojik
faktörlerini dermatolojik olarak değerlendirmek; sosyodemografik ve çevresel verilerini
sağlıklı çocuklarınkilerle karşılaştırmaktır.

Materyal
ve Metod:
Bu kesitsel prospektif çalışmada, 23 tane
labial füzyon olgusu ve 49 tane yaş cinsiyetine uygun sağlıklı denekler
dermatolojik açıdan değerlendirildi ve tümüne bir anket uygulandı.

Bulgular:
Kontrol grubunda; annelerin %34,7'si üniversiteden, labial füzyonlu çocuklarda
%34,8'i ilkokuldan mezun olmuştur. Atopik aile öyküsü ve hastaların atopik
hastalık öyküsü, labial füzyon grubunda sağlıklı kontrollere göre daha yüksekti
(p <0.001, p <0.001). Labial füzyon grubundaki olguların %60.9’unda
(n:14) ortalama 1.26 ± 1.32 (ortanca: 1.00) hafta öncesinde pre-eritematöz
lezyon şikayeti mevcuttu.  Alkol bazlı
bebek mendillerinin kullanımı labial füzyonlu grupta daha yüksekti (p = 0.035).

Sonuçlar:
Annelerin eğitim düzeyi düşük olan; aile ve kişisel atopik öyküleri ve
hastalıkları bulunan; alkol bazlı bebek mendilleri sık kullanılan çocuklarda labial
füzyon saptanmaktadır. Ayrıca, genital bölgede eritemi olan çocuklar labial
füzyonun erken tanısı ve önlenebilmesi için muayeneden sonraki ilk bir ay
boyunca takip edilmelidir.










References

  • 1. Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health 1993;29(3):235-6.
  • 2. Bacon JL. Prepubertal labial adhesions: evaluation of a referral population. Am J Obstet Gynecol 2002; 187(2):327-31.
  • 3. Gaudens DA, Moh-Ello N, Fioqbe M et al. Labial fusion in the paediatric surgery department of Yopougon University hospital (Cote d’Ivoire): 108 cases. Sante 2008; 8(1): 35-8 (French)
  • 4. Omar HA. Management of labial adhesions in prepubertal girls. J PediatrAdolescGynecol 2000;13(4):183–5.
  • 5. Mayoglou L, Dulabon L, Martin-Alguacil N. Success of treatment modalities for labial fusion: a retrospective evaluation of topical and surgical treatments. J PediatrAdolescGynecol 2009;22(4): 247-50.
  • 6. Herieka E, Dhar J. Labial adhesions following severe primary genital herpes. Sex Transm Infect 2001;77(1):75.
  • 7. Norian JM, Stratton P. Labial fusion: a rare complication of chronic graft-versus-host disease. Obstet Gynecol. 2008;112(2):437-9.
  • 8. Acer T, Otgün I, Oztürk O, Kocabaş T, Tezcan AY, Cirak A. Do hygienic factors affect labial fusion recurrence? A search for possible related etiologic factors. J Pediatr Surg. 2012 47(10):1913-8.
  • 9. Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. PediatrDermatol 2007; 24(4):373-5.
  • 10. Gibbon KL, Bewley AP, Salisbury JA. Labial fusion in children: a presenting feature of genital lichen sclerosus. PediatrDermatol 1999; 16(5):388-91.
  • 11. Hanifin JM. Atopic Dermatitis in infants and children. Pediatric Clinics North Am 1991; 38(4): 763 – 89.
  • 12. Seymour JL, Keswick BH, Hanifin JM, Jordan WP, Milligan MC. Clinical effects of diaper types on the skin of normal infants and infants with atopic dermatitis. J Am Acad Dermatol 1987;17(6): 988 – 97.
  • 13. Ehretsmann C, Schaefer P, Adam R. Cutaneous tolerance of baby wipes by infants with atopic dermatitis, and comparison of the mildness of baby wipe and water in infant skin. J Eur Acad Dermatol Venereol 2001;15: 16-21.

Dermatological aspect of labial fusion: a prospective study

Year 2019, Volume: 7 Issue: 3, 196 - 200, 18.12.2019

Abstract

Objective:
Labial fusion is a common condition in prepubertal girls and has several
complications. Some dermatological conditions were reported as etiologic factor
for this disease. The aim of this study is to evaluate the etiological factors
of labial fusion in children through a dermatologic view and to compare the
socio-demographic, and environmental data of patients with healthy children.



Material
and Method:
In this cross sectional prospective study, 23 patients with labial fusion and 49
age-sex matched healthy subjects were questioned and examined from
dermatological aspect and assessed by a questionnaire.



Results:
In the control group; 34.7% of mothers were graduated from university and in children
with labial fusion 34.8% of mothers were graduated from primary school. The
atopic family history and history of atopic diseases of patients were higher in
labial fusion group when compared with healthy controls. (p<0.001, p <0.001) There were complaints of pre-erythematous
lesions with a mean of 1.26±1.32 (median: 1.00) weeks before labial fusion in
60.9% (n:14) of  patients with labial
fusion. The alcohol based baby wipes usage was higher in group with labial
fusion (p = 0.035).



Conclusions:
Labial fusion can be diagnosed in children of mothers with lower grade
education, with family and personal atopic history and diseases, and frequent
usage of alcohol based baby wipes. Also erythema in genital area could need
follow-up in first month of visit for prevention or early diagnosis of  labial fusion.

References

  • 1. Leung AK, Robson WL, Tay-Uyboco J. The incidence of labial fusion in children. J Paediatr Child Health 1993;29(3):235-6.
  • 2. Bacon JL. Prepubertal labial adhesions: evaluation of a referral population. Am J Obstet Gynecol 2002; 187(2):327-31.
  • 3. Gaudens DA, Moh-Ello N, Fioqbe M et al. Labial fusion in the paediatric surgery department of Yopougon University hospital (Cote d’Ivoire): 108 cases. Sante 2008; 8(1): 35-8 (French)
  • 4. Omar HA. Management of labial adhesions in prepubertal girls. J PediatrAdolescGynecol 2000;13(4):183–5.
  • 5. Mayoglou L, Dulabon L, Martin-Alguacil N. Success of treatment modalities for labial fusion: a retrospective evaluation of topical and surgical treatments. J PediatrAdolescGynecol 2009;22(4): 247-50.
  • 6. Herieka E, Dhar J. Labial adhesions following severe primary genital herpes. Sex Transm Infect 2001;77(1):75.
  • 7. Norian JM, Stratton P. Labial fusion: a rare complication of chronic graft-versus-host disease. Obstet Gynecol. 2008;112(2):437-9.
  • 8. Acer T, Otgün I, Oztürk O, Kocabaş T, Tezcan AY, Cirak A. Do hygienic factors affect labial fusion recurrence? A search for possible related etiologic factors. J Pediatr Surg. 2012 47(10):1913-8.
  • 9. Cağlar MK. Serum estradiol levels in infants with and without labial adhesions: the role of estrogen in the etiology and treatment. PediatrDermatol 2007; 24(4):373-5.
  • 10. Gibbon KL, Bewley AP, Salisbury JA. Labial fusion in children: a presenting feature of genital lichen sclerosus. PediatrDermatol 1999; 16(5):388-91.
  • 11. Hanifin JM. Atopic Dermatitis in infants and children. Pediatric Clinics North Am 1991; 38(4): 763 – 89.
  • 12. Seymour JL, Keswick BH, Hanifin JM, Jordan WP, Milligan MC. Clinical effects of diaper types on the skin of normal infants and infants with atopic dermatitis. J Am Acad Dermatol 1987;17(6): 988 – 97.
  • 13. Ehretsmann C, Schaefer P, Adam R. Cutaneous tolerance of baby wipes by infants with atopic dermatitis, and comparison of the mildness of baby wipe and water in infant skin. J Eur Acad Dermatol Venereol 2001;15: 16-21.
There are 13 citations in total.

Details

Primary Language English
Journal Section Orginal Article
Authors

Ebru Yeşildağ 0000-0003-0839-1803

Gamze Erfan This is me

Gamze Varol This is me

Publication Date December 18, 2019
Published in Issue Year 2019 Volume: 7 Issue: 3

Cite

APA Yeşildağ, E., Erfan, G., & Varol, G. (2019). Dermatolojik açıdan labial füzyon: prospektif çalışma. Namık Kemal Tıp Dergisi, 7(3), 196-200.
AMA Yeşildağ E, Erfan G, Varol G. Dermatolojik açıdan labial füzyon: prospektif çalışma. NKMJ. December 2019;7(3):196-200.
Chicago Yeşildağ, Ebru, Gamze Erfan, and Gamze Varol. “Dermatolojik açıdan Labial füzyon: Prospektif çalışma”. Namık Kemal Tıp Dergisi 7, no. 3 (December 2019): 196-200.
EndNote Yeşildağ E, Erfan G, Varol G (December 1, 2019) Dermatolojik açıdan labial füzyon: prospektif çalışma. Namık Kemal Tıp Dergisi 7 3 196–200.
IEEE E. Yeşildağ, G. Erfan, and G. Varol, “Dermatolojik açıdan labial füzyon: prospektif çalışma”, NKMJ, vol. 7, no. 3, pp. 196–200, 2019.
ISNAD Yeşildağ, Ebru et al. “Dermatolojik açıdan Labial füzyon: Prospektif çalışma”. Namık Kemal Tıp Dergisi 7/3 (December 2019), 196-200.
JAMA Yeşildağ E, Erfan G, Varol G. Dermatolojik açıdan labial füzyon: prospektif çalışma. NKMJ. 2019;7:196–200.
MLA Yeşildağ, Ebru et al. “Dermatolojik açıdan Labial füzyon: Prospektif çalışma”. Namık Kemal Tıp Dergisi, vol. 7, no. 3, 2019, pp. 196-00.
Vancouver Yeşildağ E, Erfan G, Varol G. Dermatolojik açıdan labial füzyon: prospektif çalışma. NKMJ. 2019;7(3):196-200.