Maternal and neonatal outcomes related to iron deficiency anemia and serum ferritin status: A multicenter prospective study from Eastern Marmara, Turkey

Year 2019, Volume: 7 Issue: 3, 228 - 235, 18.12.2019

Çiğdem Pulatoğlu , Derya Başbuğ Bertan Akar , Hayal Şimşek Pınar Çakır Alper Başbuğ , Eray Çalışkan

Abstract

Background:
Iron
deficiency is the most common nutritional deficit in the world. More than 50%
of anemia in pregnancy results from iron deficiency and it is suggested that it
may be associated with negative pregnancy outcomes.

Aim:
The
aim of this study was to evaluate the incidence of irony deficiency anemia in
pregnancy in the East Marmara region of Turkey in order to determine its
prevalence in the country along with the effects and associations of iron
supplementation or iron status on maternal and neonatal outcomes.

Study Design: The study was designed as a prospective, longitudinal qualitative study.

Method:
This study was conducted in six centers in three provinces of the East Marmara
region(Turkey) and included a total of 1102 pregnant women. Blood samples were
collected for hematological status and serum ferritin levels during pregnancy,
and the adverse maternal and perinatal outcomes were determined.

Results:
The rate of anemia among the women included in the study was 19.8%, with 44% of
them receiving iron supplementation. The maternal age was lower in the anemic
group(26.5 vs. 27.7, p = 0.01). Selective iron use was more frequent in the
anemic group, while routine iron use was more frequent in the non-anemic
group(47.1% vs. 29.3%; p = 0.01).

Conclusions:
Iron deficiency anemia is a frequent problem in pregnancy. However, many anemic
pregnant women do not receive iron therapy. Iron supplementation may have
positive effects on some maternal and perinatal outcomes. In order to combat
iron deficiency anemia in pregnancy, widespread use of iron supplements should
be established.

Keywords

Anemia, ferritin, iron deficiency, iron supplementation, pregnancy

Demir Eksikliği Anemisi ve Serum Ferritin Düzeyi ile İlgili Maternal ve Neonatal Sonuçlar: Doğu Marmara Bölgesine Ait Çok Merkezli Bir Prospektif Çalışma, Türkiye

Abstract

Amaç:
Bu
çalışmanın amacı, demir takviyesi ve demir durumunun maternal ve neonatal
etkileri ile birlikte Türkiye'nin Doğu Marmara bölgesinde gebelikte görülen
demir eksikliği anemisi insidansını değerlendirmektir.

Yöntem:
Bu çalışma Doğu Marmara Bölgesi'nin (Türkiye) üç ilinde altı merkezde
gerçekleştirilmiş ve toplam 1102 gebeyi kapsamıştır. Gebelik sırasında
hematolojik durum ve serum ferritin düzeyleri için kan örnekleri toplandı ve
olumsuz maternal ve perinatal sonuçlar belirlendi.

Bulgular:
Çalışmaya dahil edilen kadınlarda anemi oranı % 19.8 idi ve bunların % 44'ü
demir desteği alıyordu. Maternal yaş anemik grupta daha düşüktü (26.5'e karşı
27.7, p = 0.01). Anemik grupta selektif demir kullanımı daha sık görülürken,
anemik olmayan grupta rutin demir kullanımı daha sık görüldü (% 47.1'e
karşılık% 29.3; p = 0.01).

Sonuçlar: Demir eksikliği anemisi gebelikte sık görülen
bir problemdir. Bununla birlikte, birçok anemik gebeye demir tedavisi verilmez.
Demir takviyesi, bazı maternal ve perinatal sonuçlar üzerinde olumlu etkileri olabilir.
Gebelikte demir eksikliği anemisiyle mücadele etmek için demir takviyelerinin
yaygın kullanımı sağlanmalıdır.

Keywords

Anemi, demir eksikliği, demir desteği, gebelik

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