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STREPTOMYCES KÖKENLİ ANTİBİYOTİKLERİN DÜNÜ, BUGÜNÜ VE YARINI

Year 2009, Volume: 4 Issue: 2, 48 - 60, 01.03.2009

Abstract

Mikrobiyal sekonder metabolitler; antibiyotiklerin üretiminde en büyük paya sahiptir. 1983–1994 yılları arasında keşfedilen 520 yeni ilacın, yaklaşık %39'u mikrobiyal kaynaklıdır. Şu ana kadar keşfedilen antibiyotiklerin çoğunluğu Streptomyces cinsi üyeleri tarafından üretilmektedir ve henüz bu antibiyotiklerin sadece %3'ü belirlenmiştir. Bunun nedeni ise; klasik antibiyotik araştırma metotlarının uygulanması, bazı türlerinin laboratuar koşullarında büyütülememesi ve konuyla ilgili teknolojilerin eksik oluşudur. Bu çalışmada, Streptomyces antibiyotiklerinin tipleri, endüstriyel ve biyoteknolojik önemi, antibiyotik araştırma programlarında uygulanan modern tekniklere dikkat çekerek, bu konuda ülkemizde yapılacak çalışmalar için bir önkaynak oluşturulması amaçlanmıştır.

ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE

Year 2009, Volume: 4 Issue: 2, 48 - 60, 01.03.2009

Abstract

Microbial secondary metabolites; have the largest share in the production of antibiotics. Of the 520 new drugs discovered between 1983 and 1994; approximately, 39% were originated from microbial sources. Most of the antibiotics discovered up to now, are produced by members of the genus of Streptomyces and only 3% of these antibiotics are determined yet. Reason of this is application of the classical investigation methods, some species not to grow under laboratory conditions and lack of relevant technologies. Within this study, it was aimed to state the types of Streptomyces antibiotics, industrial and biotechnological importance, modern technics in antibiotic researching programs and to form preliminary reference for future researches in our country.

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Details

Primary Language Turkish
Journal Section Biology
Authors

Mustafa Oskay

Publication Date March 1, 2009
Published in Issue Year 2009 Volume: 4 Issue: 2

Cite

APA Oskay, M. (2009). ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE. Ecological Life Sciences, 4(2), 48-60. https://doi.org/10.12739/10.12739
AMA Oskay M. ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE. Ecological Life Sciences. March 2009;4(2):48-60. doi:10.12739/10.12739
Chicago Oskay, Mustafa. “ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE”. Ecological Life Sciences 4, no. 2 (March 2009): 48-60. https://doi.org/10.12739/10.12739.
EndNote Oskay M (March 1, 2009) ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE. Ecological Life Sciences 4 2 48–60.
IEEE M. Oskay, “ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE”, Ecological Life Sciences, vol. 4, no. 2, pp. 48–60, 2009, doi: 10.12739/10.12739.
ISNAD Oskay, Mustafa. “ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE”. Ecological Life Sciences 4/2 (March 2009), 48-60. https://doi.org/10.12739/10.12739.
JAMA Oskay M. ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE. Ecological Life Sciences. 2009;4:48–60.
MLA Oskay, Mustafa. “ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE”. Ecological Life Sciences, vol. 4, no. 2, 2009, pp. 48-60, doi:10.12739/10.12739.
Vancouver Oskay M. ANTIBIOTICS DERIVED FROM THE GENUS STREPTOMYCES: PAST, PRESENT AND FUTURE. Ecological Life Sciences. 2009;4(2):48-60.