GENOTOXIC EFFECTS OF SOME FOOD ADDITIVES ON MAMMALS

Year 2018, Volume: 13 Issue: 1, 43 - 50, 21.01.2018

Pinar Aksu Kılıçle , Özlem Önen

Abstract

Food
additives are substances that are added to foods for many purposes such as
prevention of microbiological deterioration and increase of durability,
nutritive value preservation, assisting technological operations, correction of
sensory characteristics such as color, appearance, taste, smell. In this
review, it is aimed to summarize the data on the genotoxic effects of the
various food additives on the mammals and to provide a source for further work
to be done thereafter. It has been reported that food additives cause
genotoxicity compared to the results obtained from studies using various
genotoxicity tests. In vivo and in vitro studies, it has been determined that
additives increase genotoxicity and cytotoxicity depending on the applied dose.
As a result; in this review, various in vivo and in vitro studies have shown
that exposure to food additives is both genotoxic and cytotoxic on mammals,
where findings are generally parallel to each other as a result of assessed
studies.

Keywords

Food Preservatives, Mammals, Genotoxic Effect, Microbiological Deterioration, Cytotoxicity

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