Electrophoresis Applications Used in Medicine

Year 2020, Volume: 15 Issue: 1, 12 - 25, 31.01.2020

Özlem Coşkun , Özlem Öztopuz

Abstract

     Clinical
analysis distinguishing between the characteristics of healthy and pathological
conditions, the researcher to solve the mystery of the disease and to provide
the treatment of the disease in a short time is very important to save human
life. Electrophoresis routine biochemistry, hematology, or urinalysis is one of
the basic diagnostic methods commonly used in the world to obtain vitally
important information. Nonspecific changes in electrophoretic patterns are
associated with patient clinical data electrophoresis, it is very valuable in
determining the diseases which cannot be detected by routine diagnostic
studies. Many diseases such as liver, renal pathological disorders,
inflammation, proteinemia, multiple myeloma, and macroglobulinemia can be
diagnosed by electrophoresis. Recent developments in electrophoresis technology
will be the miniaturization and portability of systems. With the development of
technology, it is possible to perform electrophoresis with programming that
enables automatic execution of computerized robotic and electrophoresis
protocols. Large research is carried out to improve the systems used by
different working groups, especially the automatic electrophoresis system. The
methods explored and developed are mainly aimed at increasing the efficiency,
reproducibility and accuracy of the separation process. The aim of this review
is to emphasize the general features of electrophoresis method, clinical
diagnostic applications and future potential.

Keywords

Electrophoresis, Electrophoresis in Diagnosis, Clinical Applications, Clinical Analysis, Electrophoresis Types

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