Optic Nerve Hypoplasia; Case Report

Year 2023, , 148 - 152, 29.10.2023

Zekeriya Çetinkaya , Kuddusi Erkılıç

https://doi.org/10.56941/odutip.1315781

Abstract

Optic nerve hypoplasia (ONH) is a rare neurodevelopmental disorder described by the optic disc is abnormally small regardless of sex or race. Imaging methods are frequently used in the diagnosis. In our case, a 17-year-old male patient, came to the clinic because of a deviation in his left eye, the examination showed hypoplasia of the optic nerve in the left eye. In ON hypoplasia, reported cases may include severe Central nervous system (CNS) malformations. However, we recommend periodic systemic examinations along with occupational rehabilitation, parental education and mobility training for these unique children.

Keywords

Aplasia of optic nerve, congenital optic nerve anomaly, optic nerve

Optik sinir hipoplazisi;Olgu sunumu

Abstract

Optik sinir hipoplazisi, cinsiyet veya ırktan bağımsız olarak optik diskin anormal derecede küçük olması ile tanımlanan nadir bir nörogelişimsel bozukluktur. Tanıda görüntüleme yöntemleri sıklıkla kullanılmaktadır. Olgumuzda 17 yaşında erkek hasta sol gözünde kayma şikayeti ile kliniğe başvurdu, yapılan muayenede sol gözde optik sinir hipoplazisi saptandı. Optik sinir hipoplazisinde, bildirilen vakalar ciddi Santral sinir sistemi (SSS) malformasyonlarını içerebilir. Ancak bu çocuklar için mesleki rehabilitasyon, ebeveyn eğitimi ve hareket eğitimi ile birlikte periyodik sistemik muayeneleri önermekteyiz.

Keywords

Optik sinir hipoplazisi, konjenital optik sinir anomalisi, optik sinir

References

• Taylor D. Optic nerve axons: life and death before birth. Eye (Lond) 2005;19:499–527.
• Taylor D. Developmental abnormalities of the optic nerve and chiasm. Eye (Lond) 2007;21:1271–84.
• Sanjari MS, Ghasemi Falavarjani K, Parvaresh MM, Kharazi HH, Kashkooli MB. Bilateral aplasia of the optic nerve, chiasm, and tracts in an otherwise healthy infant. Br J Ophthalmol. 2006;90:513–4.
• Rajan RP, Deb AK, Kannan NB, Ramasamy K. Bilateral optic nerve aplasia with corpus callosum hypogenesis in an otherwise healthy child: Report of a rare case. Indian J Ophthalmol. 2019;67(7):1231-1233.
• Meire F, Delpierre I, Brachet C, Roulez F, Van Nechel C, Depasse F, et al. Non-syndromic bilateral and unilateral optic nerve aplasia: First familial occurrence and potential implication of CYP26A1 and CYP26C1 genes. Mol Vis. 2011;17:2072–2079
• Sadasivan KS, Pawar N, Ravindran M, Rengappa R. Optic nerve aplasia: A case series. Indian J Ophthalmol. 2018;66:717–9.
• Caputo R, Sodi A, Menchini U. Unilateral optic nerve aplasia associated with rudimental retinal vasculature. Int Ophthalmol. 2009;29:517–519.
• Brodsky MC, Atreides SP, Fowlkes JL, Sundin OH. Optic nerve aplasia in an infant with congenital hypopituitarism and posterior pituitary ectopia. Arch Ophthalmol. 2004;122:125–126.
• Alqahtani J. Optic nerve aplasia: A case report and literature review. J Pediatr Neurosci. 2008;3:150–153.