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Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri

Year 2024, , 902 - 923, 11.03.2024
https://doi.org/10.47495/okufbed.1283817

Abstract

Mikroplastikler (MP'ler), çevre ve insan sağlığına yönelik potansiyel riskler taşıdıklarından küresel arenada hararetle tartışılan sıcak gündem konularından biridir. Hamilelik, bebeklik ve çocukluk, çevresel maruziyet için hassas pencerelerdir. Ancak nano ve mikroplastiklere (NMP'ler) maruz kalmanın sağlık üzerindeki etkileri henüz büyük ölçüde araştırılmamış veya bu konuda spesifik olarak belirlenmiş metotlarla yapılan özellikle erken yaşam maruziyeti açısından incelemelere literatürde rastlanılmamıştır. Bu derlemede amaç, MP’ler üzerinde yapılan toksikolojik araştırmaların çocuklar özellikle de yenidoğanlar üzerinde henüz yeterince odaklanılmadığı düşünülerek bu konuda literatür boşluklarını doldurmak, ilgili sektörler, karar vericiler ve toplumun her kesiminden ferdin bilinçlendirilmesini sağlamaktır. Ayrıca, bu farkındalık sayesinde, yaşamın erken dönemlerinde plastiğe maruziyetin azaltılmasına yönelik fırsatlara vesile olacak tedbirlere yönelik öneriler sunmaktır.

References

  • Amato-Lourenço LF., Dos Santos Galvão L., de Weger LA., Hiemstra PS., Vijver MG., Mauad T. An emerging class of air pollutants: potential effects of micro-plastics to respiratory human health? Science of the Total Environment 2020; 749: 141676.
  • Amran NH., Zaid SSM., Mokhtar MH., Manaf LA., Othman S. Exposure to microplastics during early developmental stage: Review of Current Evidence. Toxics 2022; 10(10): 597.
  • Barboza LGA., Lopes C., Oliveira P., Bessa F., Otero V., Henriques B., Guilhermino, L. Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure. Science of the Total Environment 2020; 717: 134625.
  • Braun T., Ehrlich L., Henrich W., Koeppel S., Lomako I., Schwabl P., Liebmann B. Detection of microplastic in human placenta and meconium in a clinicalsetting. Pharmaceutics 2021; 13(7): 921.
  • Brennecke D., Duarte B., Paiva F., Cacador I., Canning-Clode J. Microplastics as vectors for heavy metal contamination from the marine environment. Estuarine, Coastal and Shelf Science 2016; 178: 189–195.
  • Burgos-Aceves MA., Abo-Al-Ela HG., Faggio C. Physiological and metabolic approach of plastic additive effects: immune cells responses. Journal of Hazardous Materials 2021; 404: 124114.
  • Callaghan B., McCormack C., Tottenham N., Monk C. Evidence for cognitive plasticity during pregnancy via enhanced learning and memory. Memory 2022; 30(5): 519-536.
  • Camacho M., Herrera A., Gómez M., Acosta-Dacal A., Martínez I., Henríquez-Hernández L., Luzardo OP. Organic pollutants in marine plastic debris from Canary Islands beaches. Science of the Total Environment 2019; 662: 22–31.
  • Campanale C., Massarelli C., Savino I., Locaputo V., Uricchio VF. A detailed review study on potential effects of microplastics and additives of concern on human health. International Journal of Environmental Research and Public Health 2020; 17(4): 1212.
  • Carbery M., O'Connor W, Palanisami T. Trophic transfer of microplastics and mixed contaminants in the marine food web and implications for human health. Environmental International 2018; 115: 400-409.
  • Chen Q., Lackmann C., Wang W., Seiler TB., Hollert H., Shi H. Microplastics lead to hyperactive swimming behaviour in adult zebrafish. Aquatic Toxicology 2020; 224: 105521.
  • Cho YM., Choi KH. The current status of studies of human exposure assessment of microplastics and their health effects: a rapid systematic review. Environmental Analysis Health and Toxicology 2021; 36(1): e2021004-0.
  • Cincinelli A., Scopetani C., Chelazzi D., Lombardini E., Martellini T., Katsoyiannis A., Fossi MC., Corsolini S. Microplastic in the surface waters of the Ross Sea (Antarctica): Occurrence, distribution and characterization by FTIR. Chemosphere 2017; 175: 391-400.

Effects of Microplastics on Newborn Exposure and Immune System

Year 2024, , 902 - 923, 11.03.2024
https://doi.org/10.47495/okufbed.1283817

Abstract

Microplastics (MPs) are one of the hot topics that are deeply debated in the global arena, as they pose potential risks to the environment and human health. Pregnancy, infancy and childhood are sensitive windows for environmental exposure. However, the effects of exposure to nano and microplastics (NMPs) on health have not been studied to a large extent, or studies with specific methods on this subject, especially in terms of early life exposure, have not been found in the literature. The aim of this review is to fill the gaps in the literature on this subject, considering that toxicological studies on MPs have not yet focused on children, especially newborns, and to raise awareness of the relevant sectors, decision makers and individuals from all segments of the society. In addition, through this awareness, it is to offer suggestions for measures that will lead to opportunities to reduce exposure to plastic in the early stages of life.

References

  • Amato-Lourenço LF., Dos Santos Galvão L., de Weger LA., Hiemstra PS., Vijver MG., Mauad T. An emerging class of air pollutants: potential effects of micro-plastics to respiratory human health? Science of the Total Environment 2020; 749: 141676.
  • Amran NH., Zaid SSM., Mokhtar MH., Manaf LA., Othman S. Exposure to microplastics during early developmental stage: Review of Current Evidence. Toxics 2022; 10(10): 597.
  • Barboza LGA., Lopes C., Oliveira P., Bessa F., Otero V., Henriques B., Guilhermino, L. Microplastics in wild fish from North East Atlantic Ocean and its potential for causing neurotoxic effects, lipid oxidative damage, and human health risks associated with ingestion exposure. Science of the Total Environment 2020; 717: 134625.
  • Braun T., Ehrlich L., Henrich W., Koeppel S., Lomako I., Schwabl P., Liebmann B. Detection of microplastic in human placenta and meconium in a clinicalsetting. Pharmaceutics 2021; 13(7): 921.
  • Brennecke D., Duarte B., Paiva F., Cacador I., Canning-Clode J. Microplastics as vectors for heavy metal contamination from the marine environment. Estuarine, Coastal and Shelf Science 2016; 178: 189–195.
  • Burgos-Aceves MA., Abo-Al-Ela HG., Faggio C. Physiological and metabolic approach of plastic additive effects: immune cells responses. Journal of Hazardous Materials 2021; 404: 124114.
  • Callaghan B., McCormack C., Tottenham N., Monk C. Evidence for cognitive plasticity during pregnancy via enhanced learning and memory. Memory 2022; 30(5): 519-536.
  • Camacho M., Herrera A., Gómez M., Acosta-Dacal A., Martínez I., Henríquez-Hernández L., Luzardo OP. Organic pollutants in marine plastic debris from Canary Islands beaches. Science of the Total Environment 2019; 662: 22–31.
  • Campanale C., Massarelli C., Savino I., Locaputo V., Uricchio VF. A detailed review study on potential effects of microplastics and additives of concern on human health. International Journal of Environmental Research and Public Health 2020; 17(4): 1212.
  • Carbery M., O'Connor W, Palanisami T. Trophic transfer of microplastics and mixed contaminants in the marine food web and implications for human health. Environmental International 2018; 115: 400-409.
  • Chen Q., Lackmann C., Wang W., Seiler TB., Hollert H., Shi H. Microplastics lead to hyperactive swimming behaviour in adult zebrafish. Aquatic Toxicology 2020; 224: 105521.
  • Cho YM., Choi KH. The current status of studies of human exposure assessment of microplastics and their health effects: a rapid systematic review. Environmental Analysis Health and Toxicology 2021; 36(1): e2021004-0.
  • Cincinelli A., Scopetani C., Chelazzi D., Lombardini E., Martellini T., Katsoyiannis A., Fossi MC., Corsolini S. Microplastic in the surface waters of the Ross Sea (Antarctica): Occurrence, distribution and characterization by FTIR. Chemosphere 2017; 175: 391-400.
There are 13 citations in total.

Details

Primary Language Turkish
Subjects Environmental Engineering
Journal Section REVIEWS
Authors

Gamze Doğdu 0000-0002-0278-8503

Şeyda Karabörk This is me 0000-0002-9026-4485

Mustafa Dilek This is me 0000-0002-3802-0336

Publication Date March 11, 2024
Submission Date April 17, 2023
Acceptance Date September 24, 2023
Published in Issue Year 2024

Cite

APA Doğdu, G., Karabörk, Ş., & Dilek, M. (2024). Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi, 7(2), 902-923. https://doi.org/10.47495/okufbed.1283817
AMA Doğdu G, Karabörk Ş, Dilek M. Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri. Osmaniye Korkut Ata University Journal of The Institute of Science and Techno. March 2024;7(2):902-923. doi:10.47495/okufbed.1283817
Chicago Doğdu, Gamze, Şeyda Karabörk, and Mustafa Dilek. “Mikroplastiklerin Yenidoğan Maruziyeti Ve İmmün Sistem Üzerine Etkileri”. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi 7, no. 2 (March 2024): 902-23. https://doi.org/10.47495/okufbed.1283817.
EndNote Doğdu G, Karabörk Ş, Dilek M (March 1, 2024) Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi 7 2 902–923.
IEEE G. Doğdu, Ş. Karabörk, and M. Dilek, “Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri”, Osmaniye Korkut Ata University Journal of The Institute of Science and Techno, vol. 7, no. 2, pp. 902–923, 2024, doi: 10.47495/okufbed.1283817.
ISNAD Doğdu, Gamze et al. “Mikroplastiklerin Yenidoğan Maruziyeti Ve İmmün Sistem Üzerine Etkileri”. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi 7/2 (March 2024), 902-923. https://doi.org/10.47495/okufbed.1283817.
JAMA Doğdu G, Karabörk Ş, Dilek M. Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri. Osmaniye Korkut Ata University Journal of The Institute of Science and Techno. 2024;7:902–923.
MLA Doğdu, Gamze et al. “Mikroplastiklerin Yenidoğan Maruziyeti Ve İmmün Sistem Üzerine Etkileri”. Osmaniye Korkut Ata Üniversitesi Fen Bilimleri Enstitüsü Dergisi, vol. 7, no. 2, 2024, pp. 902-23, doi:10.47495/okufbed.1283817.
Vancouver Doğdu G, Karabörk Ş, Dilek M. Mikroplastiklerin Yenidoğan Maruziyeti ve İmmün Sistem Üzerine Etkileri. Osmaniye Korkut Ata University Journal of The Institute of Science and Techno. 2024;7(2):902-23.

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