Gama ile Işınlanmış L-Trozin ve L-Trozin Metil Esteri Toz Kristallerinin Elektron Paramanyetik Rezonans (EPR) İncelenmesi

Abstract

Bu çalışmada, gama ışınları ile ışınlanmış L-Trozin(LT) ve L-Trozin Metil Esteri(LTME) toz kristallerinde oluşan serbest radikal yapılar, Elektron Paramanyetik Rezonans (EPR) spektroskopisi kullanılarak incelenmiştir. 10 kGy dozda ışınlanan örneklerin EPR spektrumları kaydedilmiş ve ışınlama sonucu örneklerde sırasıyla ĊH(NH2)COOH ve ĊH(NH2)COOCH3 radikallerinin oluştuğu tespit edilmiştir. Elde edilen EPR parametreleri simülasyon verileriyle uyumlu olup literatürdeki benzer amino asit türevleriyle karşılaştırıldığında tutarlıdır. Ayrıca örneklerin kimyasal ve biyolojik özellikleri kapsamlı bir şekilde araştırılmıştır. Bu sonuçlar, gama ışınlarının amino asit ve türevlerinde oluşturduğu yapısal değişikliklerin anlaşılması açısından önemli veriler sunmaktadır.

Keywords

• Amino Asit Türevleri
• Elektron Paramanyetik Rezonans
• Serbest Radikal

Electron Paramagnetic Resonance (EPR) Study of Gamma-Irradiated L-Tyrosine and L-Tyrosine Methyl Ester Powder Crystals

Abstract

In this study, free radical structures formed in gamma-irradiated L-Tyrosine (LT) and L-Tyrosine Methyl Ester (LTME) powder crystals were investigated using Electron Paramagnetic Resonance (EPR) spectroscopy. EPR spectra of the samples irradiated at a dose of 10 kGy were recorded, and it was determined that the radicals ĊH(NH₂)COOH and ĊH(NH₂)COOCH₃ were formed in the LT and LTME samples, respectively. The obtained EPR parameters are consistent with simulation data and show agreement with similar amino acid derivatives reported in the literature. Furthermore, the chemical and biological properties of the samples were comprehensively studied. These findings provide valuable insights into the structural changes induced by gamma irradiation in amino acids and their derivatives.

Keywords

• Amino Acid Derivatives
• Electron Paramagnetic Resonance
• Free Radicals

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