Yeni Ag-NHC Komplekslerinin Sentezi ve Karakterizasyonu

Year 2022, Volume: 5 Issue: 2, 740 - 752, 18.07.2022

Nesrin Buğday

https://doi.org/10.47495/okufbed.1053629

Abstract

Yapısal çeşitlilik ve kimyasal özellikleri nedeniyle, N-heterosiklik karbenler (NHC’ler) çok farklı alanlarda kullanılmaktadır. Son yıllarda tıbbi uygulamalarda geçiş metalleri için taşıyıcı moleküller olarak görev yapan NHC’ler antibakteriyel, antifungal ve antikanser çalışmalarında sıklıkla kullanılmaktadır. Bu çalışmada, yeni benimidazol tuzlarından, farmasötik amaçla kullanılabilecek Ag-NHC kompleksleri sentezlenmiş ve 1H-NMR, 13C-NMR ve FTIR spektroskopileri ile karakterize edilmişlerdir.

Keywords

N-Heterosiklik karben, Benzimidazol, Gümüş kompleksi

Synthesis and Characterization of New Ag-NHC Complexes

Abstract

N-heterocyclic carbenes (NHCs) are used in many different fields due to their structural diversity and chemical properties. In recent years, NHCs, which act as carrier molecules for transition metals in medical applications, are frequently used in antibacterial, antifungal, and anticancer studies. In this study, Ag-NHC complexes that can be used for pharmaceutical purposes were synthesized from new 5,6-dimethylbenzimidazole salts and characterized by 1H-NMR, 13C-NMR, and FTIR spectroscopy.

Keywords

N-heterocyclic carbene, Benzimidazolium salt, Silver complex

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