Siflutrinin Zebra Balıkları (Danio rerio)’nda Akut Toksisitesinin Araştırılması

Year 2024, Volume: 7 Issue: 3, 1021 - 1029, 25.06.2024

Gülsüm Koçak , Aysel Çağlan Günal , Aylin Sepici Dinçel

https://doi.org/10.47495/okufbed.1365490

Abstract

Siflutrin, su ekosistemlerini kirleten ve aynı zamanda potansiyel bir toksik kirletici olan sentetik bir piretroidtir. Bu çalışmada model bir organizma olan zebra balıklarında (Danio rerio) siflutrin kimyasalının 0,5, 1, 5, 10, 20 ve 50 µg/L olan dozlama çözeltilerinin 96 saat süreyle birikim değerlerinin hesaplanması amaçlanmıştır. Deneyler üç tekrarlı olarak yapılmış ve akut toksisite testinde statik test yöntemi kullanılmıştır. Aynı zamanda balıklarda tüm siflutrin konsantrasyonlarında yüzme hızında azalma, yan ve dip kısımda yüzme gibi davranış değişiklikleri gözlemlenmiştir. Siflutrinin akut toksisite testlerinden elde edilen veriler Probit Analizi İstatistik Yöntemi kullanılarak değerlendirilmiştir. Zebra balığının 96 saatlik LC50 değeri 3,61 µg/L olarak hesaplanmıştır.

Keywords

Siflutrin, Zebrabalığı, Danio rerio, LC50, Piretroid

Ethical Statement

Gazi Üniversitesi Hayvan Deneyleri Yerel Etik Kurulu tarafından ( Kod: G.Ü.ET-20.071) onaylanmıştır.

Supporting Institution

Gazi Üniversitesi Bilimsel Araştırmalar Proje Birimi

Project Number

FBE-2023-8307

Investigation of Acute Toxicity of Cyfluthrin on Zebrafish (Danio rerio)

Abstract

Cyfluthrin is a synthetic pyrethroid that pollutes aquatic ecosystems and is also a potential toxic pollutant. Zebrafish (Danio rerio) were used in acute toxicity tests for bioassays. 96-hour LC50 values were determined for zebrafish. Experiments were performed in triplicate and the static test method of acute toxicity test was used. At the same time, behavioral changes were observed at each cyfluthrin concentration in fish. Data from cyfluthrin acute toxicity tests were evaluated using the Probit Analysis Statistical Method. The 96-h LC50 value for zebrafish was calculated as 3.61 µg/L.

Keywords

Cyfluthrin, Zebrafish, Danio rerio, LC50, Pyrethroid

Project Number

FBE-2023-8307

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