Case Report
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Conservative management of cervical ectopic pregnancy: A case report and review of literature

Year 2024, Volume: 41 Issue: 2, 446 - 449, 19.05.2024

Abstract

Ectopic pregnancies, occurring in approximately 1-2% of cases, are typically found within the fallopian tube. Among these instances, cervical ectopic pregnancies constitute less than 1% of cases, with the majority observed within the endocervical canal. This study presents a case of cervical ectopic pregnancy following in vitro fertilization (IVF), treated with a single dose of methotrexate. A 23-year-old woman who has been married for 4 years with a history of infertility presents with complaints of abdominal pain for 2 days and vaginal spotting as bleeding, following her last menstrual period, at 5 weeks and 3 days of pregnancy. In her medical history, the patient mentions having low ovarian reserve (AMH 6.73 pmol/L), which led to in vitro fertilization (IVF) transfer 22 days ago. Due to the patient's young age and it being her first pregnancy, medical treatment with methotrexate (MTX) was decided. MTX was administered at a dose of 50 mg/m² (100 mg of intravenous MTX in 100 ml of 0.9% NaCl). Experiences in cervical ectopic pregnancies predominantly stem from case-based experiences. Thus, when planning treatment for cervical ectopic pregnancy, a conservative or minimally invasive approach may be more appropriate, tailored to the patient's characteristics whenever possible.

References

  • Kraemer B, Abele H, Hahn M, Wallwiener D, Rajab TK, Hornung R. Cervical ectopic pregnancy on the portio: conservative case management and clinical review. Fertil Steril. 2008;90(5):2011.e1-4. doi:10.1016/j.fertnstert.2008.06.018
  • Tanos V, ElAkhras S, Kaya B. Hysteroscopic management of cervical pregnancy: Case series and review of the literature. J Gynecol Obstet Hum Reprod. 2019;48(4):247-253. doi:10.1016/j.jogoh.2018.05.001
  • Sheng S, Zhang H, Pan Z, Li T, Wang H, Shi M, Wang F. Treatment of heterotopic cervical pregnancy by ultrasound-guided hysteroscopy: a case report and literature review. Medicine (Baltimore). 2022;101(48):e32177. doi:10.1097/MD.0000000000032177
  • Javedani Masroor M, Zarei A, Sheibani H. Conservative Management of Cervical Pregnancy with the Administration of Methotrexate and Potassium Chloride: A Case Report. Case Rep Obstet Gynecol. 2022:1352868. doi:10.1155/2022/1352868
  • Coulter-Nile S, Balachandar K, Ward H. A diagnostic dilemma of an 18-week cervical ectopic pregnancy: A case report. Case Rep Womens Health. 2022;13:33:e00385. doi:10.1016/j.crwh.2022.e00385
  • Fouda A, Enayat A, Ahmed WE. Conservative management of a viable cervical ectopic pregnancy with systemic and multiple local methotrexate injections: A case report. Eur J Contracept Health Care. 2022;27(3):265-268. doi:10.1080/13625187.2022.2026325
  • Stabile G, Mangino FP, Romano F, Zinicola G, Ricci G. Ectopic Cervical Pregnancy: Treatment Route. Medicina (Kaunas). 2020;56(6):293. doi:10.3390/medicina56060293
  • Guzowski G, Sieroszewski P. Invasive ultrasound in the management of cervical ectopic pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;172:7-9. doi:10.10.16/j.ejogrb.2013.10.016
  • Mori KH, Tavares BV, Yela DA, Baccaro LFC, Juliato CRT. Experience of a Tertiary Service in the Treatment of Women with Cervical Pregnancy. Rev Bras Ginecol Obstet. 2022;44(11):1014-1020. doi:10.1055/s-0042-175954
  • Mininni C, Garibaldi S, Fornari L, Domenici L, Cattani R, Bottone P. Effective combined treatment in ectopic cervical pregnancy preserving fertility: a case report and literature review. Eur Rev Med Pharmacol Sci. 2012;25(12):4190-4197. doi:10.2635/eurrev_202106_26121.
Year 2024, Volume: 41 Issue: 2, 446 - 449, 19.05.2024

Abstract

References

  • Kraemer B, Abele H, Hahn M, Wallwiener D, Rajab TK, Hornung R. Cervical ectopic pregnancy on the portio: conservative case management and clinical review. Fertil Steril. 2008;90(5):2011.e1-4. doi:10.1016/j.fertnstert.2008.06.018
  • Tanos V, ElAkhras S, Kaya B. Hysteroscopic management of cervical pregnancy: Case series and review of the literature. J Gynecol Obstet Hum Reprod. 2019;48(4):247-253. doi:10.1016/j.jogoh.2018.05.001
  • Sheng S, Zhang H, Pan Z, Li T, Wang H, Shi M, Wang F. Treatment of heterotopic cervical pregnancy by ultrasound-guided hysteroscopy: a case report and literature review. Medicine (Baltimore). 2022;101(48):e32177. doi:10.1097/MD.0000000000032177
  • Javedani Masroor M, Zarei A, Sheibani H. Conservative Management of Cervical Pregnancy with the Administration of Methotrexate and Potassium Chloride: A Case Report. Case Rep Obstet Gynecol. 2022:1352868. doi:10.1155/2022/1352868
  • Coulter-Nile S, Balachandar K, Ward H. A diagnostic dilemma of an 18-week cervical ectopic pregnancy: A case report. Case Rep Womens Health. 2022;13:33:e00385. doi:10.1016/j.crwh.2022.e00385
  • Fouda A, Enayat A, Ahmed WE. Conservative management of a viable cervical ectopic pregnancy with systemic and multiple local methotrexate injections: A case report. Eur J Contracept Health Care. 2022;27(3):265-268. doi:10.1080/13625187.2022.2026325
  • Stabile G, Mangino FP, Romano F, Zinicola G, Ricci G. Ectopic Cervical Pregnancy: Treatment Route. Medicina (Kaunas). 2020;56(6):293. doi:10.3390/medicina56060293
  • Guzowski G, Sieroszewski P. Invasive ultrasound in the management of cervical ectopic pregnancy. Eur J Obstet Gynecol Reprod Biol. 2014;172:7-9. doi:10.10.16/j.ejogrb.2013.10.016
  • Mori KH, Tavares BV, Yela DA, Baccaro LFC, Juliato CRT. Experience of a Tertiary Service in the Treatment of Women with Cervical Pregnancy. Rev Bras Ginecol Obstet. 2022;44(11):1014-1020. doi:10.1055/s-0042-175954
  • Mininni C, Garibaldi S, Fornari L, Domenici L, Cattani R, Bottone P. Effective combined treatment in ectopic cervical pregnancy preserving fertility: a case report and literature review. Eur Rev Med Pharmacol Sci. 2012;25(12):4190-4197. doi:10.2635/eurrev_202106_26121.
There are 10 citations in total.

Details

Primary Language English
Subjects Obstetrics and Gynaecology
Journal Section Case Report
Authors

Emel Çağlayan 0000-0002-4290-6412

Batuhan Üstün 0000-0002-2113-1232

Publication Date May 19, 2024
Submission Date February 17, 2024
Acceptance Date April 30, 2024
Published in Issue Year 2024 Volume: 41 Issue: 2

Cite

APA Çağlayan, E., & Üstün, B. (2024). Conservative management of cervical ectopic pregnancy: A case report and review of literature. Journal of Experimental and Clinical Medicine, 41(2), 446-449.
AMA Çağlayan E, Üstün B. Conservative management of cervical ectopic pregnancy: A case report and review of literature. J. Exp. Clin. Med. May 2024;41(2):446-449.
Chicago Çağlayan, Emel, and Batuhan Üstün. “Conservative Management of Cervical Ectopic Pregnancy: A Case Report and Review of Literature”. Journal of Experimental and Clinical Medicine 41, no. 2 (May 2024): 446-49.
EndNote Çağlayan E, Üstün B (May 1, 2024) Conservative management of cervical ectopic pregnancy: A case report and review of literature. Journal of Experimental and Clinical Medicine 41 2 446–449.
IEEE E. Çağlayan and B. Üstün, “Conservative management of cervical ectopic pregnancy: A case report and review of literature”, J. Exp. Clin. Med., vol. 41, no. 2, pp. 446–449, 2024.
ISNAD Çağlayan, Emel - Üstün, Batuhan. “Conservative Management of Cervical Ectopic Pregnancy: A Case Report and Review of Literature”. Journal of Experimental and Clinical Medicine 41/2 (May 2024), 446-449.
JAMA Çağlayan E, Üstün B. Conservative management of cervical ectopic pregnancy: A case report and review of literature. J. Exp. Clin. Med. 2024;41:446–449.
MLA Çağlayan, Emel and Batuhan Üstün. “Conservative Management of Cervical Ectopic Pregnancy: A Case Report and Review of Literature”. Journal of Experimental and Clinical Medicine, vol. 41, no. 2, 2024, pp. 446-9.
Vancouver Çağlayan E, Üstün B. Conservative management of cervical ectopic pregnancy: A case report and review of literature. J. Exp. Clin. Med. 2024;41(2):446-9.