Synthesis of N-acetyl-4-methyl-benzenesulfonamide from Chloramine-T

Year 2020, Volume: 10 Issue: 2, 117 - 124, 31.12.2020

Latif Kelebekli

Abstract

The synthesis of N-acetyl-4-methyl-benzenesulfonamide is reported. Reaction of N-chloro-p-toluenesulfonamide by acetyl chloride (AcCl) in the presence or absence of OsO4 gave the desired compound. The synthesized compound was characterized by FT-IR, 1H-NMR, 13C-NMR and HRMS analyses.
Bu çalışmada, N-asetil-4-metil-benzensülfonamidin sentezi rapor edildi. N-kloro-p-toluensülfonamidin OsO4 varlığında veya yokluğunda asetil klorür (AcCl) ile reaksiyonu beklenen bileşiği verdi. Sentezlenen bileşik FT-IR, 1H-NMR, 13C-NMR ve HRMS analizleri ile karakterize edildi.

Keywords

N-acylsulfonamide, N-acylation, chloramine-T, acetyl chloride

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