Perikard Tutulumu Olan Multiple Myelom Olgusu

Year 2022, , 887 - 889, 28.11.2022

Nur Oguz Davutoglu Hava Üsküdar Teke Fatih Yaman Neslihan Andıc Eren Gunduz

https://doi.org/10.20515/otd.1109622

Abstract

Multipl miyelom (MM), tüm hematolojik kanserlerin yaklaşık %10'unu oluşturan kemik iliğinin atipik plazma hücre bozukluğudur. MM’da ekstramedüller hastalık %6-20 oranında görülürken kardiyak ve perikardiyal tutulum varlığı ise nadirdir. Kardiyak veya perikardiyal tutulum meydana geldiğinde, kalp tamponadına ilerleme hastaların %60'ında gerçekleşir. Biz de otolog kök hücre nakli sonrası çok nadir görülen perikard tutulumu ile nüks olan olguyu sunacağız.

Keywords

multiple myelom, relaps, perikardiyal tutulum

Multiple Myeloma Case with Pericardial Involvement

Abstract

Multiple myeloma (MM) is an atypical plasma cell dyscrasia in the bone marrow (BM) which accounts for about 10% of all hematological malignancies. While extramedullary disease (EMD) is reported at a ratio of 6-20% in MM, cardiac and pericardial involvement is rare. In the event of cardiac or pericardiac involvement, on the other hand, progression into cardiac tamponade takes place in 60% of the patients. We will present a very rare case of recurrence with pericardial involvement after autologous stem cell transplantation

Keywords

multiple myeloma, relapse, pericardial involvement

References

• Referance1. Kyle RA, Rajkumar SV. Multiple myeloma. Blood 2008;111(6):2962–72.
• Referance2. Chen T, Kim Taubman K, Xiao H et al. Cardiac tamponade in multiple myeloma: A pictorial case review of FDG PET/CT findings. Journal of Medical Imaging and Radiation Oncology 2020;64: 377–378.
• Referance3. Abelman W, Virchis A, Yong K. Extramedullary myeloma representing as a pericardial effusion with tamponade: two case reports and a further review of 19 cases in the literature. Leuk Lymphoma 2005;46(1):137–42.
• Referance4. Coakley M, Yeneneh B, Rosenthal A, et al. Extramedullary cardiac multiple myeloma-a case report and contemporary review of the literature. Clin Lymphoma Myeloma Leuk 2016;16(5):246–252.
• Referance5. Skipina TM, Sane DC, Cui C et al. A plasma cell-based pericardial effusion leading to tamponade in a patient with multiple myeloma -a case report and review of the literature. Cardiovasc Pathol 2019; 40: 41–46.
• Referans6. Arat M, Ulusoy V, Demirer T, et al. An unusual presentation of plasma cell dyscrasias: cardiac tamponade due to myelomatous infiltration. Leuk Lymphoma 2002;43(1):145–148.