Evaluation of Oral and Dental Anomalies in Patients with Childhood Cancer Treatment

Öz

The aim of this study is to evaluate the patients who have completed childhood cancer treatment in comparison with healthy children in terms of oral dental health and dental anomalies. A total of 101 patients, including 50 patients with cancer treatment (case group) and 51 healthy individuals (control group) without any systemic disease, were included in the study. In the clinical examination of the patients, soft and hard tissues in the mouth were examined, enamel defects, dental disorders, DMFT / dmft, plaque index, gingival index scores were evaluated. In the radiographic examination, root development of the teeth, apical closure, tooth deficiencies were recorded. The analysis of the data obtained was performed with IBM SPSS Statistics 21. T-test, one-way analysis of variance (ANOVA) and Chi-Square analysis were used. The mean DMFT score was 3.20 ± 3.33 in the case group and 1.98 ± 2.72 in the control group. There was a statistically significant difference between the two groups (p = 0.047). There was no statistically significant difference between the case and control groups in terms of the Silness plaque index and gingival bleeding index score (p> 0.05). Among the developmental dental defects, the short V-shaped root development was observed on average 4 times more in patients under 5 years of age. The patients with microdontia were found to be about 3 times more in the group under 5 years of age than in the group over 5 years of age. It was found that oral hygiene was worse, DMFT scores were higher in the case group compared to the control group, and some dental anomalies were more common in cancer treatments under 5 years old. Further studies are needed in larger sample groups.

Anahtar Kelimeler

• Childhood cancer, dental anomaly, cancer therapy, side effect

Çocukluk Çağı Kanser Tedavisi Tamamlanmış Hastalarda Oral ve Dental Anomalilerin Değerlendirilmesi

Öz

Amaç: Bu çalışmanın amacı çocukluk çağı kanser tedavisi tamamlanmış hastaları, ağız diş sağlığı durumları ve dental anomaliler açısından sağlıklı çocuklarla karşılaştırılmalı şekilde değerlendirmektir. Gereç-Yöntemler: Çalışmaya kanser tedavisi tamamlanmış 50 hasta ve herhangi bir sistemik hastalığı bulunmayan 51 sağlıklı birey olmak üzere toplamda 101 kişi dahil edildi. Hastaların klinik muayenesinde ağızdaki yumuşak ve sert dokular incelendi, mine defektleri, dental bozukluklar, DMFT/dmft, plak indeksi, gingival indeks skorları değerlendirildi. Radyografik muayene ile dişlerin kök gelişimleri, apikal kapanma durumu, diş eksiklikleri kaydedildi. Elde edilen verilerin analizi IBM SPSS Statistics 21 ile gerçekleştirildi. t testi, tek yönlü varyans analizi (ANOVA) ve Ki-Kare analizleri kullanıldı. Bulgular: DMFT skoru ortalaması vaka grubunda 3,20 ± 3,33 iken kontrol grubunda 1,98 ± 2,72 idi. İki grup arasında istatistiksel olarak anlamlı farklılık olduğu belirlendi (p=0,047). Silness plak indeksi ve Gingival kanama indeks skoru açısından vaka ve kontrol grupları arasında istatistiksel olarak anlamlı bir fark saptanmamıştır (p>0,05). Gelişimsel dental defektler arasında kısa V şekilli durmuş kök gelişimi 5 yaş altında tedavi alan hastalarda ortalama dört kat fazla görüldü. Mikrodonti saptanan hastaların ise 5 yaş altında tedavi alan grupta, 5 yaş üstünde tedavi alan gruba göre yaklaşık üç kat fazla olduğu görüldü. Sonuç: Kanser tedavisi almış grupta kontrol grubuna göre ağız hijyeninin daha kötü, DMFT skorlarının daha yüksek olduğu ve 5 yaş altında alınan kanser tedavilerinde bazı dental anomalilerin daha sık olduğu tespit edilmiştir. Bu konuda daha geniş örneklem gruplarında ileri çalışmalara ihtiyaç duyulmaktadır.

Anahtar Kelimeler

• Çocukluk çağı kanseri
• dental anomali
• kanser tedavisi
• yan etki

Kaynakça

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