Covid 19 İçin Buzlu Cam Opasitesi ve Konsolidasyon Belirtileri Prevalansinin Meta Analizi

Öz

Bu çalışmada, bilgisayarlı göğüs tomografisinde en yaygın görüntüleme bulguları olan buzlu cam opasitesi (GGO) ve konsolidasyon sonuçları incelenerek daha kesin Covid-19 tespitini sağlamak için yayınlanan çalışmalardan elde edilen sonuçlar kullanılarak meta analiz yönteminin uygulanması amaçlanmıştır. Çalışmaya gerçek zamanlı polimeraz zincir reaksiyonu (rRT-PCR) pozitif vakaların görüntü özelliklerini bildiren ve SARS-Cov-2 enfeksiyonunu doğrulayan yayınlanmış hakemli makaleler dahil edilmiştir. Bu makalelerin çalışma türü vaka serisi, geriye dönük veya ileriye dönük kohort şeklindedir. Araştırma kapsamındaki çalışmalara, Covid-19, şiddetli akut solunum yolu sendromu corona virüsü 2 (SARS-Cov-2), bilgisayarlı göğüs tomografisi, konsolidasyon ve GGO anahtar kelimelerinin radyografik araştırma veri tabanı Secure Australia (RNSA), The Science Direct ve National Library of Medicine'de araştırılması ile ulaşılmıştır. Arama terimleri sonucunda üç veri tabanından toplam 310 makale toplandı ve makaleler tarandı. Buzlu cam opasitesi ve konsolidasyon bilgilerinin olmaması nedeniyle 250 makale çıkarıldı. Geriye kalan makalelerden, çalışma türü nedeniyle 24 makale, gün kriterini sağlamaması nedeniyle 7 makale, eksik ve yanlış veriler nedeniyle 9 makale çıkarıldı. Sonuçta 20 makale meta-analiz çalışmamıza dahil edildi. Bilgisayarlı göğüs tomografisi pozitif olan bulgularda, buzlu cam opasitesinin 5 güne kadar mevcut olduğu, beşinci ve sonraki günlerde konsolidasyona dönüştüğü görülmüştür. Analiz sonuçlarına göre; Covid-19'un erken evresi için buzlu cam opasitesinin prevalansı %82 ve konsolidasyonun prevalansı %40’tır.

Anahtar Kelimeler

• Meta analiz
• Covid-19
• rRT-PCR test
• bilgisayarlı göğüs tomografisi

The Prevalence of Ground-Glass Opacity and Consolidation Symptoms of Covid-19 By Meta-Analysis

Öz

In this study, it was aimed to apply the meta-analysis method of the results obtained from the published studies to provide a more precise Covid-19 detection by examining the results of ground glass opacity (GGO) and consolidation, which are the most common imaging findings in chest computed tomography (CT). Published peer-reviewed articles reporting the image characteristics of real-time reverse transcription–polymerase chain reaction (rRT-PCR) positive cases and confirming Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) infection were included in the study. The study type of articles were case series, retrospective or prospective cohort studies. The studies under the scope of the research were reached from the National Library of Medicine, the research network for a Secure Australia (RNSA) and The Science Direct databases by searching the keywords Covid-19, SARS-Cov-2, computed chest tomography, Consolidation and GGO. As a result of the search terms, in total 310 articles were collected from three databases and articles were scanned, 250 articles were removed due to lack of GGO and Consolidation information, 24 studies were eliminated due to study type, 7 studies were unsuitable for day criteria, and 9 studies were eliminated due to missing and incorrect data. After all, 20 studies were included in our meta-analysis study. In the positive CT findings, it is known that the GGO is present for up to 5 days, the GGO turns into consolidation on the fifth and the following days, and according to the analysis result; for the early stage of Covid-19, the GGO Prevalence is 82% and Consolidation Prevalence is 40%.

Anahtar Kelimeler

• Meta-analysis
• Covid-19
• rRT-PCR test
• chest computed tomography

Kaynakça

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